γδ CD8+ T cells and novel genetic variants in ZAP70 deficiency

Combined immunodeficiency caused by pathogenic variants in the ZAP70 C-terminal SH2 domain

(2023) Cédric Mongellaz et al.   Frontiers in Immunology

The link between rheumatic disorders and inborn errors of immunity

(2023) Georgios Sogkas et al.   EBioMedicine

A boy with a novel homozygous ZAP70 mutation presenting with a dermatological phenotype and postnatal decrease in CD8 + T cells

(2022) Royala Babayeva et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

Characterization of Expanded Gamma Delta T Cells from Atypical X-SCID Patient Reveals Preserved Function and IL2RG-Mediated Signaling

(2022) Elina A. Tuovinen et al.   JOURNAL OF CLINICAL IMMUNOLOGY

ZAP70 holds the key to kinetic proofreading for TCR ligand discrimination

(2022) Mahima Swamy   NATURE IMMUNOLOGY

An allosteric hot spot in the tandem-SH2 domain of ZAP-70 regulates T-cell signaling

(2020) Kaustav Gangopadhyay et al.   BIOCHEMICAL JOURNAL

Clinical, Immunological, and Genetic Features in 49 Patients With ZAP-70 Deficiency: A Systematic Review

(2020) Niusha Sharifinejad et al.   Frontiers in Immunology

IL-17-producing γδ T cells switch migratory patterns between resting and activated states

(2017) Duncan R. McKenzie et al.   Nature Communications

A novel human autoimmune syndrome caused by combined hypomorphic and activating mutations in ZAP-70

(2016) Alice Y. Chan et al.   JOURNAL OF EXPERIMENTAL MEDICINE

β2-Microglobulin deficiency causes a complex immunodeficiency of the innate and adaptive immune system

(2015) Ömür Ardeniz et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Defining combined immunodeficiency

(2012) Chaim M. Roifman et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A leaky mutation in CD3D differentially affects αβ and γδ T cells and leads to a Tαβ–Tγδ+B+NK+ human SCID

(2011) Juana Gil et al.   JOURNAL OF CLINICAL INVESTIGATION

Characterization of ζ-associated protein, 70 kd (ZAP70)–deficient human lymphocytes

(2010) Chaim M. Roifman et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Loops Govern SH2 Domain Specificity by Controlling Access to Binding Pockets

(2010) T. Kaneko et al.   Science Signaling