Glycine supplementation in vitro enhances porcine preimplantation embryo cell number and decreases apoptosis but does not lead to live births

PS48 can replace bovine serum albumin in pig embryo culture medium, and improve in vitro embryo development by phosphorylating AKT

(2015) Lee D. Spate et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance

(2015) Dohoon Kim et al.   NATURE

Gene-edited pigs are protected from porcine reproductive and respiratory syndrome virus

(2015) Kristin M Whitworth et al.   NATURE BIOTECHNOLOGY

Arginine increases development of in vitro-produced porcine embryos and affects the protein arginine methyltransferase–dimethylarginine dimethylaminohydrolase–nitric oxide axis

(2015) Bethany K. Redel et al.   REPRODUCTION FERTILITY AND DEVELOPMENT

Serine and glycine metabolism in cancer

(2014) Ivano Amelio et al.   TRENDS IN BIOCHEMICAL SCIENCES

Sec-containing TrxR1 is essential for self-sufficiency of cells by control of glucose-derived H2O2

(2014) X Peng et al.   Cell Death & Disease

Glycine consumption and mitochondrial serine hydroxymethyltransferase in cancer cells: The heme connection

(2013) Martino L. di Salvo et al.   MEDICAL HYPOTHESES

Glycine Decarboxylase Activity Drives Non-Small Cell Lung Cancer Tumor-Initiating Cells and Tumorigenesis

(2012) Wen Cai Zhang et al.   CELL

Dipeptide forms of glycine support mouse preimplantation embryo development in vitro and provide protection against high media osmolality

(2012) Molly Moravek et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Replacement of bovine serum albumin with N-methyl-D-aspartic acid and homocysteine improves development, but not live birth

(2012) L.D. Spate et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

A role for the Warburg effect in preimplantation embryo development: Metabolic modification to support rapid cell proliferation

(2012) Rebecca L. Krisher et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Piglets produced from cloned blastocysts cultured in vitro with GM-CSF

(2012) Kiho Lee et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Systems Biology, Metabolomics, and Cancer Metabolism

(2012) M. Tomita et al.   SCIENCE

Metabolite Profiling Identifies a Key Role for Glycine in Rapid Cancer Cell Proliferation

(2012) M. Jain et al.   SCIENCE

Regulation of oocyte mitochondrial DNA copy number by follicular fluid, EGF, and neuregulin 1 during in vitro maturation affects embryo development in pigs

(2012) J. Mao et al.   THERIOGENOLOGY

Glycolysis in preimplantation development is partially controlled by the Warburg Effect

(2011) Bethany K. Redel et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

1 ARGININE SUPPLEMENTATION IN VITRO INCREASES PORCINE EMBRYO DEVELOPMENT AND AFFECTS�mRNA TRANSCRIPT EXPRESSION

(2011) B. K. Bauer et al.   REPRODUCTION FERTILITY AND DEVELOPMENT

Glucose and glycine synergistically enhance the in vitro development of porcine blastocysts in a chemically defined medium

(2011) Tomomi Mito et al.   REPRODUCTION FERTILITY AND DEVELOPMENT

Transcriptional Profiling by Deep Sequencing Identifies Differences in mRNA Transcript Abundance in In Vivo-Derived Versus In Vitro-Cultured Porcine Blastocyst Stage Embryos1

(2010) Bethany K. Bauer et al.   BIOLOGY OF REPRODUCTION

Porcine oocytes denuded before maturation can develop to the blastocyst stage if provided a cumulous cell-derived coculture system1

(2010) X. Zhang et al.   JOURNAL OF ANIMAL SCIENCE

The Control of the Metabolic Switch in Cancers by Oncogenes and Tumor Suppressor Genes

(2010) A. J. Levine et al.   SCIENCE

Disruption of the CFTR Gene Produces a Model of Cystic Fibrosis in Newborn Pigs

(2008) C. S. Rogers et al.   SCIENCE