Cell interactions and genetic regulation that contribute to testicular Leydig cell development and differentiation

Androgen receptor roles in spermatogenesis and infertility

(2015) Laura O'Hara et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Identification of the Link Between the Hypothalamo-Pituitary Axis and the Testicular Orphan Nuclear Receptor NR0B2 in Adult Male Mice

(2015) Aurélie Vega et al.   ENDOCRINOLOGY

GATA4 Is a Key Regulator of Steroidogenesis and Glycolysis in Mouse Leydig Cells

(2015) Anja Schrade et al.   ENDOCRINOLOGY

Combined Loss of the GATA4 and GATA6 Transcription Factors in Male Mice Disrupts Testicular Development and Confers Adrenal-Like Function in the Testes

(2015) Maria B. Padua et al.   ENDOCRINOLOGY

Autocrine androgen action is essential for Leydig cell maturation and function, and protects against late-onset Leydig cell apoptosis in both mice and men

(2015) Laura O’Hara et al.   FASEB JOURNAL

Morphological and functional maturation of Leydig cells: from rodent models to primates

(2015) K. J. Teerds et al.   HUMAN REPRODUCTION UPDATE

Fetal Leydig Cells Persist as an Androgen-Independent Subpopulation in the Postnatal Testis

(2015) Yuichi Shima et al.   MOLECULAR ENDOCRINOLOGY

Reprogramming of Sertoli cells to fetal-like Leydig cells byWt1ablation

(2015) Lianjun Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Wt1 dictates the fate of fetal and adult Leydig cells during development in the mouse testis

(2014) Qing Wen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Regulation of the Proliferation and Differentiation of Leydig Stem Cells in the Adult Testis1

(2014) Hana M. Odeh et al.   BIOLOGY OF REPRODUCTION

The Nuclear Receptor NR2F2 Activates Star Expression and Steroidogenesis in Mouse MA-10 and MLTC-1 Leydig Cells1

(2014) Raifish E. Mendoza-Villarroel et al.   BIOLOGY OF REPRODUCTION

Sertoli cells control peritubular myoid cell fate and support adult Leydig cell development in the prepubertal testis

(2014) D. Rebourcet et al.   DEVELOPMENT

The INSL3 gene is a direct target for the orphan nuclear receptor, COUP-TFII, in Leydig cells

(2014) R. E. Mendoza-Villarroel et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Sertoli Cells Maintain Leydig Cell Number and Peritubular Myoid Cell Activity in the Adult Mouse Testis

(2014) Diane Rebourcet et al.   PLoS One

Fetal programming of adult Leydig cell function by androgenic effects on stem/progenitor cells

(2014) K. R. Kilcoyne et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NGF induces adult stem Leydig cells to proliferate and differentiate during Leydig cell regeneration

(2013) Lei Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Aristaless Related Homeobox Gene, Arx, Is Implicated in Mouse Fetal Leydig Cell Differentiation Possibly through Expressing in the Progenitor Cells

(2013) Kanako Miyabayashi et al.   PLoS One

Dynamics of Notch Pathway Expression during Mouse Testis Post-Natal Development and along the Spermatogenic Cycle

(2013) Daniel Murta et al.   PLoS One

Gata4 Is Required for Formation of the Genital Ridge in Mice

(2013) Yueh-Chiang Hu et al.   PLoS Genetics

Identification, Proliferation, and Differentiation of Adult Leydig Stem Cells

(2012) Erin Stanley et al.   ENDOCRINOLOGY

Contribution of Leydig and Sertoli Cells to Testosterone Production in Mouse Fetal Testes

(2012) Yuichi Shima et al.   MOLECULAR ENDOCRINOLOGY

Redundant and Differential Roles of Transcription Factors Gli1 and Gli2 in the Development of Mouse Fetal Leydig Cells1

(2011) Ivraym Barsoum et al.   BIOLOGY OF REPRODUCTION

Stem Leydig Cell Differentiation: Gene Expression During Development of the Adult Rat Population of Leydig Cells1

(2011) Erin L. Stanley et al.   BIOLOGY OF REPRODUCTION

Two distinct origins for Leydig cell progenitors in the fetal testis

(2011) Tony DeFalco et al.   DEVELOPMENTAL BIOLOGY

Gonadal transactivation of STARD1, CYP11A1 and HSD3B

(2011) Steven et al.   Frontiers in Bioscience-Landmark

Androgen receptor signalling in peritubular myoid cells is essential for normal differentiation and function of adult Leydig cells

(2011) M. Welsh et al.   INTERNATIONAL JOURNAL OF ANDROLOGY

Functional Cooperation Between GATA Factors and cJUN on the Star Promoter in MA-10 Leydig Cells

(2011) L. J. Martin et al.   JOURNAL OF ANDROLOGY

Transcription of platelet-derived growth factor receptor   in Leydig cells involves specificity protein 1 and 3

(2011) F. Bergeron et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Human testicular insulin-like factor 3: in relation to development, reproductive hormones and andrological disorders

(2010) K. Bay et al.   INTERNATIONAL JOURNAL OF ANDROLOGY

Localization and regulation of aromatase liver receptor homologue-1 in the developing rat testis

(2010) Jayne Sierens et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Oestrogens and spermatogenesis

(2010) S. Carreau et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The Notch signaling pathway: Transcriptional regulation at Notch target genes

(2009) T. Borggrefe et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Developmental expression ofSmoc1andSmoc2suggests potential roles in fetal gonad and reproductive tract differentiation

(2009) Dorothy E. Pazin et al.   DEVELOPMENTAL DYNAMICS

Leydig cells: From stem cells to aging

(2009) Haolin Chen et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Notch signaling maintains Leydig progenitor cells in the mouse testis

(2008) H. Tang et al.   DEVELOPMENT

Regulation of P450c17 Expression in the Early Embryo Depends on GATA Factors

(2008) Yimin Shi et al.   ENDOCRINOLOGY

Antiandrogen Exposurein UteroDisrupts Expression of Desert Hedgehog and Insulin-Like Factor 3 in the Developing Fetal Rat Testis

(2008) Leon J. S. Brokken et al.   ENDOCRINOLOGY

The PDGF signaling pathway controls multiple steroid-producing lineages

(2008) J. Schmahl et al.   GENES & DEVELOPMENT

The Orphan Nuclear Receptor NUR77 Regulates Hormone-InducedStARTranscription in Leydig Cells through Cooperation with Ca2+/Calmodulin-Dependent Protein Kinase I

(2008) Luc J. Martin et al.   MOLECULAR ENDOCRINOLOGY

Essential Roles of COUP-TFII in Leydig Cell Differentiation and Male Fertility

(2008) Jun Qin et al.   PLoS One

Effect of germ cell depletion on levels of specific mRNA transcripts in mouse Sertoli cells and Leydig cells

(2008) P J O'Shaughnessy et al.   REPRODUCTION

Molecular mechanisms of testosterone action in spermatogenesis☆

(2008) William H. Walker   STEROIDS