Ankyrin-G isoform imbalance and interneuronopathy link epilepsy and bipolar disorder

A Loss-of-Function Variant in a Minor Isoform of ANK3 Protects Against Bipolar Disorder and Schizophrenia

(2016) Timothy Hughes et al.   BIOLOGICAL PSYCHIATRY

Suicide attempts in bipolar disorders: comprehensive review of 101 reports

(2015) L. Tondo et al.   ACTA PSYCHIATRICA SCANDINAVICA

An Ankyrin-G N-terminal Gate and Protein Kinase CK2 Dually Regulate Binding of Voltage-gated Sodium and KCNQ2/3 Potassium Channels

(2015) Mingxuan Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

M-current preservation contributes to anticonvulsant effects of valproic acid

(2015) Hee Yeon Kay et al.   JOURNAL OF CLINICAL INVESTIGATION

Pathway-driven discovery of epilepsy genes

(2015) Jeffrey Noebels   NATURE NEUROSCIENCE

Meta-Analysis Revives Genome-Wide Association Studies in Epilepsy

(2015) Annapurna Poduri   Epilepsy Currents

Single-Gene Determinants of Epilepsy Comorbidity

(2015) Jeffrey L. Noebels   Cold Spring Harbor Perspectives in Medicine

Heteromeric Kv7.2/7.3 Channels Differentially Regulate Action Potential Initiation and Conduction in Neocortical Myelinated Axons

(2014) A. Battefeld et al.   JOURNAL OF NEUROSCIENCE

A supercritical density of Na+ channels ensures fast signaling in GABAergic interneuron axons

(2014) Hua Hu et al.   NATURE NEUROSCIENCE

Ancient trade between India and Indonesia

(2014) A. Calo   SCIENCE

Record-linkage studies of the coexistence of epilepsy and bipolar disorder

(2014) Clare J. Wotton et al.   SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY

Genome-wide association study reveals two new risk loci for bipolar disorder

(2014) Thomas W. Mühleisen et al.   Nature Communications

Gene–Environment Interactions in Severe Mental Illness

(2014) Rudolf Uher   Frontiers in Psychiatry

Suicide risk in people with epilepsy taking antiepileptic drugs

(2013) Marco Mula et al.   BIPOLAR DISORDERS

Homozygous and heterozygous disruptions of ANK3: at the crossroads of neurodevelopmental and psychiatric disorders

(2013) Z. Iqbal et al.   HUMAN MOLECULAR GENETICS

E-cadherin Polarity Is Determined by a Multifunction Motif Mediating Lateral Membrane Retention through Ankyrin-G and Apical-lateral Transcytosis through Clathrin

(2013) Paul M Jenkins et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetics of bipolar disorder

(2013) Nick Craddock et al.   LANCET

Treatment of bipolar disorder

(2013) John R Geddes et al.   LANCET

Paradoxical proepileptic response to NMDA receptor blockade linked to cortical interneuron defect in stargazer mice

(2013) Atul Maheshwari et al.   Frontiers in Cellular Neuroscience

Epilepsy, suicidality, and psychiatric disorders: A bidirectional association

(2012) Dale C. Hesdorffer et al.   ANNALS OF NEUROLOGY

The ANK3 Bipolar Disorder Gene Regulates Psychiatric-Related Behaviors That Are Modulated by Lithium and Stress

(2012) Melanie P. Leussis et al.   BIOLOGICAL PSYCHIATRY

Re-sequencing of ankyrin 3 exon 48 and case-control association analysis of rare variants in bipolar disorder type I

(2012) Glenn A Doyle et al.   BIPOLAR DISORDERS

Emotion processing and regulation in bipolar disorder: a review

(2012) Jennifer Townsend et al.   BIPOLAR DISORDERS

Do mood instability symptoms in epilepsy represent formal bipolar disorder?

(2012) Connie Lau et al.   EPILEPSIA

Epilepsy across the spectrum: Promoting health and understanding.

(2012) Mary Jane England et al.   EPILEPSY & BEHAVIOR

Division and subtraction by distinct cortical inhibitory networks in vivo

(2012) Nathan R. Wilson et al.   NATURE

Hospitalization for psychiatric disorders before and after onset of unprovoked seizures/epilepsy

(2012) C. Adelow et al.   NEUROLOGY

Parvalbumin-Expressing Interneurons Linearly Transform Cortical Responses to Visual Stimuli

(2012) Bassam V. Atallah et al.   NEURON

Association analysis of ANK3 gene variants in nordic bipolar disorder and schizophrenia case-control samples

(2011) Martin Tesli et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4

(2011)   NATURE GENETICS

Evidence for cis-acting regulation of ANK3 and CACNA1C gene expression

(2010) Emma M Quinn et al.   BIPOLAR DISORDERS

Development of NMDA NR2 subunits and their roles in critical period maturation of neocortical GABAergic interneurons

(2010) Zhi Zhang et al.   Developmental Neurobiology

Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes

(2010) Hsiao-Tuan Chao et al.   NATURE

Developmental maturation of excitation and inhibition balance in principal neurons across four layers of somatosensory cortex

(2010) Z. Zhang et al.   NEUROSCIENCE

Validating, augmenting and refining genome-wide association signals

(2009) John P. A. Ioannidis et al.   NATURE REVIEWS GENETICS

Psychiatric Comorbidities in Epilepsy: Identification and Treatment

(2009) Irene García-Morales et al.   NEUROLOGIST

Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry

(2009) L. J. Scott et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Two variants in Ankyrin 3 (ANK3) are independent genetic risk factors for bipolar disorder

(2008) T G Schulze et al.   MOLECULAR PSYCHIATRY

The molecular neurobiology of depression

(2008) Vaishnav Krishnan et al.   NATURE

Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder

(2008) Manuel A R Ferreira et al.   NATURE GENETICS