A rare missense mutation in CHRNA4 associates with smoking behavior and its consequences

Large-scale whole-genome sequencing of the Icelandic population

(2015) Daniel F Gudbjartsson et al.   NATURE GENETICS

Genome-wide meta-analysis reveals common splice site acceptor variant in CHRNA4 associated with nicotine dependence

(2015) D B Hancock et al.   Translational Psychiatry

Smoking habits in the randomised Danish Lung Cancer Screening Trial with low-dose CT: final results after a 5-year screening programme

(2014) Haseem Ashraf et al.   THORAX

Nicotine exploits a COPI-mediated process for chaperone-mediated up-regulation of its receptors

(2013) Brandon J. Henderson et al.   JOURNAL OF GENERAL PHYSIOLOGY

Molecular Mechanisms Underlying Behaviors Related to Nicotine Addiction

(2013) M. R. Picciotto et al.   Cold Spring Harbor Perspectives in Medicine

Positive allosteric modulation of α4β2 nAChR agonist induced behaviour

(2012) F. Rode et al.   BRAIN RESEARCH

Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls

(2012) Maria N. Timofeeva et al.   HUMAN MOLECULAR GENETICS

From Men to Mice: CHRNA5/CHRNA3, Smoking Behavior and Disease

(2012) Jennifer J. Ware et al.   NICOTINE & TOBACCO RESEARCH

Rare Nonsynonymous Variants in Alpha-4 Nicotinic Acetylcholine Receptor Gene Protect Against Nicotine Dependence

(2011) Pingxing Xie et al.   BIOLOGICAL PSYCHIATRY

Commentary: Gene-environment interactions and smoking-related cancers

(2010) T. E. Thorgeirsson et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Sequence variants at CHRNB3–CHRNA6 and CYP2A6 affect smoking behavior

(2010) Thorgeir E Thorgeirsson et al.   NATURE GENETICS

Nicotine is a Selective Pharmacological Chaperone of Acetylcholine Receptor Number and Stoichiometry. Implications for Drug Discovery

(2009) Henry A. Lester et al.   AAPS Journal

PLAURpolymorphisms and lung function in UK smokers

(2009) Ceri E Stewart et al.   BMC Medical Genetics

Association between a 15q25 gene variant, smoking quantity and tobacco-related cancers among 17 000 individuals

(2009) Esther H Lips et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Sequence variants at the TERT-CLPTM1L locus associate with many cancer types

(2009) Thorunn Rafnar et al.   NATURE GENETICS

A Genome-Wide Investigation of SNPs and CNVs in Schizophrenia

(2009) Anna C. Need et al.   PLoS Genetics

Genetics of Smoking Behavior and Its Consequences: The Role of Nicotinic Acetylcholine Receptors

(2008) Thorgeir E. Thorgeirsson et al.   BIOLOGICAL PSYCHIATRY

A comprehensive analysis of phase I and phase II metabolism gene polymorphisms and risk of non-small cell lung cancer in smokers

(2008) Shanbeh Zienolddiny et al.   CARCINOGENESIS

α-5/α-3 nicotinic receptor subunit alleles increase risk for heavy smoking

(2008) W Berrettini et al.   MOLECULAR PSYCHIATRY

A variant associated with nicotine dependence, lung cancer and peripheral arterial disease

(2008) Thorgeir E. Thorgeirsson et al.   NATURE

A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25

(2008) Rayjean J. Hung et al.   NATURE

Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1

(2008) Christopher I Amos et al.   NATURE GENETICS