Sulforaphane Attenuates AOM/DSS-Induced Colorectal Tumorigenesis in Mice via Inhibition of Intestinal Inflammation

Ursolic Acid Suppresses Colorectal Cancer by Down-Regulation of Wnt/β-Catenin Signaling Pathway Activity

(2023) Hui Zhao et al.   Journal of Agricultural and Food Chemistry

Berberine is a suppressor of Hedgehog signaling cascade in colorectal cancer

(2023) Qiang Sun et al.   PHYTOMEDICINE

Midazolam exhibits antitumour and anti-inflammatory effects in a mouse model of pancreatic ductal adenocarcinoma

(2022) Yukino Oshima et al.   BRITISH JOURNAL OF ANAESTHESIA

Sulforaphane Modulates the Inflammation and Delays Neurodegeneration on a Retinitis Pigmentosa Mice Model

(2022) Antolín Canto et al.   Frontiers in Pharmacology

Identification of environmental factors that promote intestinal inflammation

(2022) Liliana M. Sanmarco et al.   NATURE

Inflammasome signaling in colorectal cancer

(2022) Bhesh Raj Sharma et al.   Translational Research

Emodin Inhibits Inflammation, Carcinogenesis, and Cancer Progression in the AOM/DSS Model of Colitis-Associated Intestinal Tumorigenesis

(2021) Yunsha Zhang et al.   Frontiers in Oncology

Acetylcholine ameliorates colitis by promoting IL-10 secretion of monocytic myeloid-derived suppressor cells through the nAChR/ERK pathway

(2021) Wanwei Zheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cancer-preventive effect of phenethyl isothiocyanate through tumor microenvironment regulation in a colorectal cancer stem cell xenograft model

(2021) Ji Min Shin et al.   PHYTOMEDICINE

MDSC in Mice and Men: Mechanisms of Immunosuppression in Cancer

(2021) Christophe Vanhaver et al.   Journal of Clinical Medicine

Density of CD3+ and CD8+ Cells in the Microenvironment of Colorectal Cancer according to Prediagnostic Physical Activity

(2021) David Renman et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Attenuation of experimentally induced atopic dermatitis in mice by sulforaphane: effect on inflammation and apoptosis

(2021) Abdullah Alyoussef   TOXICOLOGY MECHANISMS AND METHODS

A Complex Metabolic Network Confers Immunosuppressive Functions to Myeloid-Derived Suppressor Cells (MDSCs) within the Tumour Microenvironment

(2021) Francesca Hofer et al.   Cells

Sulforaphane reduces intracellular survival of Staphylococcus aureus in macrophages through inhibition of JNK and p38 MAPK‑induced inflammation

(2020) Therese Deramaudt et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Lipids in the tumor microenvironment: From cancer progression to treatment

(2020) Kevin C. Corn et al.   PROGRESS IN LIPID RESEARCH

HDAC9 deficiency promotes tumor progression by decreasing the CD8+ dendritic cell infiltration of the tumor microenvironment

(2020) Yongling Ning et al.   Journal for ImmunoTherapy of Cancer

Increased myeloid-derived suppressor cells in patients with myelodysplastic syndromes suppress CD8+ T lymphocyte function through the STAT3-ARG1 pathway

(2020) Xiao Qi et al.   LEUKEMIA & LYMPHOMA

Sulforaphane modulates CX3CL1/CX3CR1 axis and inflammation in palmitic acid-induced cell injury in C2C12 skeletal muscle cells

(2020) Yousef Faridvand et al.   MOLECULAR BIOLOGY REPORTS

Role of myeloid-derived suppressor cells in the promotion and immunotherapy of colitis-associated cancer

(2020) Yungang Wang et al.   Journal for ImmunoTherapy of Cancer

CD11b+Ly6G+ myeloid-derived suppressor cells promote liver regeneration in a murine model of major hepatectomy

(2019) Ido Nachmany et al.   FASEB JOURNAL

Deciphering myeloid-derived suppressor cells: isolation and markers in humans, mice and non-human primates

(2019) Luca Cassetta et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Anti-inflammatory and anti-oxidant effects of combination between sulforaphane and acetaminophen in LPS-stimulated RAW 264.7 macrophage cells

(2019) Linh Dieu Vuong et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Immune checkpoint protein VISTA regulates antitumor immunity by controlling myeloid cell-mediated inflammation and immunosuppression

(2019) Wenwen Xu et al.   Cancer Immunology Research

Co-Treatment with Sulforaphane and Nano-Metformin Molecules Accelerates Apoptosis in HER2+ Breast Cancer Cells by Inhibiting Key Molecules

(2019) A. Keshandehghan et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Fluoroaryl analogs of sulforaphane – A group of compounds of anticancer and antimicrobial activity

(2019) Tomasz Cierpiał et al.   BIOORGANIC CHEMISTRY

Reprogramming the murine colon cancer microenvironment using lentivectors encoding shRNA against IL-10 as a component of a potent DC-based chemoimmunotherapy

(2018) Joanna Rossowska et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Isothiocyanates for Human Health

(2018) Richard Mithen et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Interleukin-10 produced by myeloid-derived suppressor cells is critical for the induction of Tregs and attenuation of rheumatoid inflammation in mice

(2018) Min-Jung Park et al.   Scientific Reports

Tumor-induced MDSC act via remote control to inhibit L-selectin-dependent adaptive immunity in lymph nodes

(2016) Amy W Ku et al.   eLife

Norepinephrine-induced myeloid-derived suppressor cells block T-cell responsesviageneration of reactive oxygen species

(2015) Yufeng Liu et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

The global burden of IBD: from 2015 to 2025

(2015) Gilaad G. Kaplan   Nature Reviews Gastroenterology & Hepatology

Catestatin decreases macrophage function in two mouse models of experimental colitis

(2014) Mohammad F. Rabbi et al.   BIOCHEMICAL PHARMACOLOGY

Interleukin-10 Receptor Signaling in Innate Immune Cells Regulates Mucosal Immune Tolerance and Anti-Inflammatory Macrophage Function

(2014) Dror S. Shouval et al.   IMMUNITY

Cancer-Expanded Myeloid-Derived Suppressor Cells Induce Anergy of NK Cells through Membrane-Bound TGF- 1

(2014) H. Li et al.   JOURNAL OF IMMUNOLOGY

Neutrophil infiltration favors colitis-associated tumorigenesis by activating the interleukin-1 (IL-1)/IL-6 axis

(2014) Y Wang et al.   Mucosal Immunology

Cruciferous Vegetables and Risk of Colorectal Neoplasms: A Systematic Review and Meta-Analysis

(2013) Genevieve Tse et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Sulforaphane: translational research from laboratory bench to clinic

(2013) Christine A Houghton et al.   NUTRITION REVIEWS

Investigating Intestinal Inflammation in DSS-induced Model of IBD

(2012) Janice J. Kim et al.   Jove-Journal of Visualized Experiments

Chronic intestinal inflammation: inflammatory bowel disease and colitis-associated colon cancer

(2012) Deborah C. Rubin et al.   Frontiers in Immunology

Colitis-associated cancer: the dark side of inflammatory bowel disease

(2011) S. Danese et al.   GUT

Inflammation and Colon Cancer

(2010) Janoš Terzić et al.   GASTROENTEROLOGY

Myeloid-Derived Suppressor Cells Down-Regulate L-Selectin Expression on CD4+ and CD8+ T Cells

(2009) E. M. Hanson et al.   JOURNAL OF IMMUNOLOGY

Oral sulforaphane increases Phase II antioxidant enzymes in the human upper airway

(2008) Marc A. Riedl et al.   CLINICAL IMMUNOLOGY

Myeloid-Derived Suppressor Cells in Inflammatory Bowel Disease: A New Immunoregulatory Pathway

(2008) Lydia A. Haile et al.   GASTROENTEROLOGY

Arginine regulation by myeloid derived suppressor cells and tolerance in cancer: mechanisms and therapeutic perspectives

(2008) Paulo C. Rodríguez et al.   IMMUNOLOGICAL REVIEWS