Global TLR2 and 4 deficiency in mice impacts bone resorption, inflammatory markers and atherosclerosis to polymicrobial infection

Periodontal Pathogens Invade Gingiva and Aortic Adventitia and Elicit Inflammasome Activation in αvβ6 Integrin-Deficient Mice

(2015) Irina M. Velsko et al.   INFECTION AND IMMUNITY

Toll-Like Receptor 9-Mediated Inflammation Triggers Alveolar Bone Loss in Experimental Murine Periodontitis

(2015) Paul D. Kim et al.   INFECTION AND IMMUNITY

Polymicrobial Oral Infection with Four Periodontal Bacteria Orchestrates a Distinct Inflammatory Response and Atherosclerosis in ApoEnull Mice

(2015) Sasanka S. Chukkapalli et al.   PLoS One

Chronic oral infection with major periodontal bacteria Tannerella forsythia modulates systemic atherosclerosis risk factors and inflammatory markers

(2015) Sasanka S. Chukkapalli et al.   Pathogens and Disease

Porphyromonas gingivalis Manipulates Complement and TLR Signaling to Uncouple Bacterial Clearance from Inflammation and Promote Dysbiosis

(2014) Tomoki Maekawa et al.   Cell Host & Microbe

Invasion of Oral and Aortic Tissues by Oral Spirochete Treponema denticola in ApoE−/−Mice Causally Links Periodontal Disease and Atherosclerosis

(2014) Sasanka S. Chukkapalli et al.   INFECTION AND IMMUNITY

Transcriptional Responses of Treponema denticola to Other Oral Bacterial Species

(2014) Juni Sarkar et al.   PLoS One

Active Invasion of Oral and Aortic Tissues by Porphyromonas gingivalis in Mice Causally Links Periodontitis and Atherosclerosis

(2014) Irina M. Velsko et al.   PLoS One

Porphyromonas gingivalis and Treponema denticola Exhibit Metabolic Symbioses

(2014) Kheng H. Tan et al.   PLoS Pathogens

A periodontal pathogen Treponema denticola hijacks the Fusobacterium nucleatum -driven host response

(2013) Ji Eun Shin et al.   IMMUNOLOGY AND CELL BIOLOGY

Toll-Like Receptor 9 Promotes Cardiac Inflammation and Heart Failure during Polymicrobial Sepsis

(2013) Ralph Lohner et al.   MEDIATORS OF INFLAMMATION

Polymicrobial Infection with Major Periodontal Pathogens Induced Periodontal Disease and Aortic Atherosclerosis in Hyperlipidemic ApoEnull Mice

(2013) Mercedes F. Rivera et al.   PLoS One

Inflammation in Atherosclerosis

(2012) Peter Libby   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Toll-Like Receptor 7 Protects From Atherosclerosis by Constraining “Inflammatory” Macrophage Activation

(2012) Maria Salagianni et al.   CIRCULATION

The FomA Porin from Fusobacterium nucleatum Is a Toll-Like Receptor 2 Agonist with Immune Adjuvant Activity

(2012) Deana N. Toussi et al.   Clinical and Vaccine Immunology

Protective Role for TLR4 Signaling in Atherosclerosis Progression as Revealed by Infection with a Common Oral Pathogen

(2012) C. Hayashi et al.   JOURNAL OF IMMUNOLOGY

Mechanism and implications of CXCR4-mediated integrin activation byPorphyromonas gingivalis

(2012) G. Hajishengallis et al.   Molecular Oral Microbiology

Filifactor alocis Has Virulence Attributes That Can Enhance Its Persistence under Oxidative Stress Conditions and Mediate Invasion of Epithelial Cells by Porphyromonas gingivalis

(2011) A. Wilson Aruni et al.   INFECTION AND IMMUNITY

Unexpected protective role for Toll-like receptor 3 in the arterial wall

(2011) J. E. Cole et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of Toll-Like Receptor 4 in Intimal Foam Cell Accumulation in Apolipoprotein E–Deficient Mice

(2010) Mie Higashimori et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Pathogen-Mediated Inflammatory Atherosclerosis Is Mediated in Part via Toll-Like Receptor 2-Induced Inflammatory Responses

(2010) Chie Hayashi et al.   Journal of Innate Immunity

The atheroprotective properties of Hsp70: a role for Hsp70-endothelial interactions?

(2009) A. Graham Pockley et al.   CELL STRESS & CHAPERONES

Lipoprotein Accumulation in Macrophages via Toll-Like Receptor-4–Dependent Fluid Phase Uptake

(2009) Soo-Ho Choi et al.   CIRCULATION RESEARCH

Involvement of Toll-Like Receptors 2 and 4 in the Innate Immune Response to Treponema denticola and Its Outer Sheath Components

(2009) G. Nussbaum et al.   INFECTION AND IMMUNITY

Treponema denticola Suppresses Expression of Human  -Defensin-3 in Gingival Epithelial Cells through Inhibition of the Toll-Like Receptor 2 Axis

(2009) J. E. Shin et al.   INFECTION AND IMMUNITY

Bacterial DNA Activates Endothelial Cells and Promotes Neutrophil Adherence through TLR9 Signaling

(2009) D. El Kebir et al.   JOURNAL OF IMMUNOLOGY

Increased endothelial expression of Toll-like receptor 2 at sites of disturbed blood flow exacerbates early atherogenic events

(2008) Adam E. Mullick et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Toll-Like Receptor-2 Mediates Diet and/or Pathogen Associated Atherosclerosis: Proteomic Findings

(2008) Monika Madan et al.   PLoS One

Pathogen induction of CXCR4/TLR2 cross-talk impairs host defense function

(2008) G. Hajishengallis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA