Droplet digital PCR of circulating tumor cells from colorectal cancer patients can predict KRAS mutations before surgery

Detection of KRAS mutations in circulating tumor cells from patients with metastatic colorectal cancer

(2015) Marcilei EC Buim et al.   CANCER BIOLOGY & THERAPY

Emergence of Drug Tolerance in Cancer Cell Populations: An Evolutionary Outcome of Selection, Nongenetic Instability, and Stress-Induced Adaptation

(2015) R. H. Chisholm et al.   CANCER RESEARCH

Digital PCR analysis of circulating nucleic acids

(2015) Irena Hudecova   CLINICAL BIOCHEMISTRY

Noninvasive Detection of Activating Estrogen Receptor 1 (ESR1) Mutations in Estrogen Receptor-Positive Metastatic Breast Cancer

(2015) D. S. Guttery et al.   CLINICAL CHEMISTRY

Liquid biopsy

(2015) Isabelle Gingras et al.   CURRENT OPINION IN ONCOLOGY

Challenges in circulating tumor cell detection by the CellSearch system

(2015) Kiki C. Andree et al.   Molecular Oncology

Non-invasive sensitive detection of KRAS and BRAF mutation in circulating tumor cells of colorectal cancer patients

(2015) Nur-Afidah Mohamed Suhaimi et al.   Molecular Oncology

The biology of circulating tumor cells

(2015) K Pantel et al.   ONCOGENE

Epithelial–mesenchymal transition in colorectal cancer metastasis: A system review

(2015) Hui Cao et al.   PATHOLOGY RESEARCH AND PRACTICE

Accessing Genetic Information with Liquid Biopsies

(2015) Xuyu Cai et al.   TRENDS IN GENETICS

Clinical applications of next generation sequencing in cancer: from panels, to exomes, to genomes

(2015) Tony Shen et al.   Frontiers in Genetics

Mutational Analysis of Circulating Tumor Cells from Colorectal Cancer Patients and Correlation with Primary Tumor Tissue

(2015) Anna Lyberopoulou et al.   PLoS One

The predictive value ofKRAS, NRAS, BRAF, PIK3CAand PTEN for anti-EGFR treatment in metastatic colorectal cancer: A systematic review and meta-analysis

(2014) Christina Therkildsen et al.   ACTA ONCOLOGICA

Circulating tumor cells

(2014) Cristina Raimondi et al.   CANCER BIOLOGY & THERAPY

Clinical Relevance of KRAS-Mutated Subclones Detected with Picodroplet Digital PCR in Advanced Colorectal Cancer Treated with Anti-EGFR Therapy

(2014) P. Laurent-Puig et al.   CLINICAL CANCER RESEARCH

Molecular Characterization of Circulating Tumor Cells: Holy Grail for Personalized Cancer Treatment?

(2014) E. S. Lianidou   CLINICAL CHEMISTRY

Circulating Tumor DNA as a Liquid Biopsy for Cancer

(2014) E. Heitzer et al.   CLINICAL CHEMISTRY

Biology, detection, and clinical implications of circulating tumor cells

(2014) S. A. Joosse et al.   EMBO Molecular Medicine

Clinical validation of the detection of KRAS and BRAF mutations from circulating tumor DNA

(2014) Alain R Thierry et al.   NATURE MEDICINE

Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies

(2014) C. Bettegowda et al.   Science Translational Medicine

Resistance to Anti-EGFR Therapy in Colorectal Cancer: From Heterogeneity to Convergent Evolution

(2014) S. Misale et al.   Cancer Discovery

Circulating tumour cells and circulating free nucleic acid as prognostic and predictive biomarkers in colorectal cancer

(2013) S.H. Lim et al.   CANCER LETTERS

Real-time Liquid Biopsy in Cancer Patients: Fact or Fiction?

(2013) K. Pantel et al.   CANCER RESEARCH

Circulating tumor cells in colorectal cancer patients

(2013) Francesco Torino et al.   CANCER TREATMENT REVIEWS

Multiplex Picodroplet Digital PCR to Detect KRAS Mutations in Circulating DNA from the Plasma of Colorectal Cancer Patients

(2013) V. Taly et al.   CLINICAL CHEMISTRY

Technologies for detection of circulating tumor cells: facts and vision

(2013) Catherine Alix-Panabières et al.   LAB ON A CHIP

Absolute quantification by droplet digital PCR versus analog real-time PCR

(2013) Christopher M Hindson et al.   NATURE METHODS

Circulating Breast Tumor Cells Exhibit Dynamic Changes in Epithelial and Mesenchymal Composition

(2013) M. Yu et al.   SCIENCE

KRAS mutational status analysis of peripheral blood isolated circulating tumor cells in metastatic colorectal patients

(2013) CRISTINA GUTIÉRREZ et al.   Oncology Letters

Heterogeneity of Epidermal Growth Factor Receptor Status and Mutations of KRAS/PIK3CA in Circulating Tumor Cells of Patients with Colorectal Cancer

(2012) C. Gasch et al.   CLINICAL CHEMISTRY

KRASandBRAFmutation status in circulating colorectal tumor cells and their correlation with primary and metastatic tumor tissue

(2012) Bianca Mostert et al.   INTERNATIONAL JOURNAL OF CANCER

Mutant KRAS Codon 12 and 13 Alleles in Patients With Metastatic Colorectal Cancer: Assessment As Prognostic and Predictive Biomarkers of Response to Panitumumab

(2012) Marc Peeters et al.   JOURNAL OF CLINICAL ONCOLOGY

Microsieve lab-chip device for rapid enumeration and fluorescence in situ hybridization of circulating tumor cells

(2012) Li Shi Lim et al.   LAB ON A CHIP

Comprehensive molecular characterization of human colon and rectal cancer

(2012)   NATURE

High-Throughput Droplet Digital PCR System for Absolute Quantitation of DNA Copy Number

(2011) Benjamin J. Hindson et al.   ANALYTICAL CHEMISTRY

Comparison of Sanger Sequencing, Pyrosequencing, and Melting Curve Analysis for the Detection of KRAS Mutations

(2010) Athanasios C. Tsiatis et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Prognostic significance of circulating tumor cells in patients with metastatic colorectal cancer

(2009) S. J. Cohen et al.   ANNALS OF ONCOLOGY

KRAS Mutation

(2009) Wilbur A. Franklin et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Application of COLD-PCR for improved detection of KRAS mutations in clinical samples

(2009) Zhuang Zuo et al.   MODERN PATHOLOGY

High-Resolution Melting Analysis for Rapid Detection ofKRAS, BRAF,andPIK3CAGene Mutations in Colorectal Cancer

(2008) Lisa Simi et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Relationship of Circulating Tumor Cells to Tumor Response, Progression-Free Survival, and Overall Survival in Patients With Metastatic Colorectal Cancer

(2008) Steven J. Cohen et al.   JOURNAL OF CLINICAL ONCOLOGY

Wild-TypeKRASIs Required for Panitumumab Efficacy in Patients With Metastatic Colorectal Cancer

(2008) Rafael G. Amado et al.   JOURNAL OF CLINICAL ONCOLOGY