The ginger component 6-shogaol prevents TNF-α-induced barrier loss via inhibition of PI3K/Akt and NF-κB signaling

Proinflammatory cytokine-induced tight junction remodeling through dynamic self-assembly of claudins

(2014) Christopher T. Capaldo et al.   MOLECULAR BIOLOGY OF THE CELL

6-Shogaol inhibits breast and colon cancer cell proliferation through activation of peroxisomal proliferator activated receptor γ (PPARγ)

(2013) Boon Shing Tan et al.   CANCER LETTERS

[6]-Shogaol inhibits the production of proinflammatory cytokines via regulation of NF-κB and phosphorylation of JNK in HMC-1 cells

(2013) Youngjoo Sohn et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Claudins and the Modulation of Tight Junction Permeability

(2013) Dorothee Günzel et al.   PHYSIOLOGICAL REVIEWS

Amelioration of IFN-γ and TNF-α-Induced Intestinal Epithelial Barrier Dysfunction by Berberine via Suppression of MLCK-MLC Phosphorylation Signaling Pathway

(2013) Min Cao et al.   PLoS One

Claudin 1 Mediates TNFα-Induced Gene Expression and Cell Migration in Human Lung Carcinoma Cells

(2012) Atsushi Shiozaki et al.   PLoS One

Expression profiling of claudins in the human gastrointestinal tract in health and during inflammatory bowel disease

(2012) Anke L. Lameris et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Anti-apoptotic effect of claudin-1 on TNF-α-induced apoptosis in human breast cancer MCF-7 cells

(2012) Yang Liu et al.   TUMOR BIOLOGY

Claudin-1 expression in airway smooth muscle exacerbates airway remodeling in asthmatic subjects

(2011) Hiroyuki Fujita et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Crosstalk in NF-κB signaling pathways

(2011) Andrea Oeckinghaus et al.   NATURE IMMUNOLOGY

Tumor necrosis factor alpha increases epithelial barrier permeability by disrupting tight junctions in Caco-2 cells

(2010) W. Cui et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

TNF-α/NF-κB/Snail pathway in cancer cell migration and invasion

(2010) Y Wu et al.   BRITISH JOURNAL OF CANCER

6-Shogaol, an active constituent of ginger, inhibits breast cancer cell invasion by reducing matrix metalloproteinase-9 expression via blockade of nuclear factor-κB activation

(2010) H Ling et al.   BRITISH JOURNAL OF PHARMACOLOGY

Claudin-2, a component of the tight junction, forms a paracellular water channel

(2010) R. Rosenthal et al.   JOURNAL OF CELL SCIENCE

TNFα-induced and berberine-antagonized tight junction barrier impairment via tyrosine kinase, Akt and NFκB signaling

(2010) Maren Amasheh et al.   JOURNAL OF CELL SCIENCE

Epithelial NF-κB Enhances Transmucosal Fluid Movement by Altering Tight Junction Protein Composition after T Cell Activation

(2009) Yueming Tang et al.   AMERICAN JOURNAL OF PATHOLOGY

TNFα up-regulates claudin-2 expression in epithelial HT-29/B6 cells via phosphatidylinositol-3-kinase signaling

(2009) J. Mankertz et al.   CELL AND TISSUE RESEARCH

6-Shogaol inhibits monosodium urate crystal-induced inflammation – An in vivo and in vitro study

(2009) Evan Prince Sabina et al.   FOOD AND CHEMICAL TOXICOLOGY

Comparative antioxidant and anti-inflammatory effects of [6]-gingerol, [8]-gingerol, [10]-gingerol and [6]-shogaol

(2009) Swarnalatha Dugasani et al.   JOURNAL OF ETHNOPHARMACOLOGY

Proinflammatory cytokines tumor necrosis factor-α and interferon-γ alter tight junction structure and function in the rat parotid gland Par-C10 cell line

(2008) Olga J. Baker et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Pharmacokinetics of 6-Gingerol, 8-Gingerol, 10-Gingerol, and 6-Shogaol and Conjugate Metabolites in Healthy Human Subjects

(2008) S. M. Zick et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

NF-κB in inflammatory bowel disease

(2008) I. Atreya et al.   JOURNAL OF INTERNAL MEDICINE

6-Shogaol suppressed lipopolysaccharide-induced up-expression of iNOS and COX-2 in murine macrophages

(2008) Min-Hsiung Pan et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Some phytochemical, pharmacological and toxicological properties of ginger (Zingiber officinale Roscoe): A review of recent research

(2007) Badreldin H. Ali et al.   FOOD AND CHEMICAL TOXICOLOGY