Acute single non-sedative doses of NOP receptor agonists affect acquisition of object location memory but repeated high doses do not induce long-lasting deficits

The NOP Receptor System in Neurological and Psychiatric Disorders: Discrepancies, Peculiarities and Clinical Progress in Developing Targeted Therapies

(2021) Lawrence Toll et al.   CNS DRUGS

Sex Differences in Nociceptin/Orphanin FQ Peptide Receptor-Mediated Pain and Anxiety Symptoms in a Preclinical Model of Post-traumatic Stress Disorder

(2019) Yong Zhang et al.   Frontiers in Psychiatry

Agonist-selective NOP receptor phosphorylation correlates in vitro and in vivo and reveals differential post-activation signaling by chemically diverse agonists

(2019) Anika Mann et al.   Science Signaling

Nociceptin impairs acquisition of novel object recognition memory in perirhinal cortex

(2019) Ren-wen Han et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Potent and selective NOP receptor activation reduces cocaine self‐administration in rats by lowering hedonic set point

(2019) Andrea Cippitelli et al.   ADDICTION BIOLOGY

The Nociceptin Receptor (NOP) Agonist AT-312 Blocks Acquisition of Morphine- and Cocaine-Induced Conditioned Place Preference in Mice

(2018) Nurulain T. Zaveri et al.   Frontiers in Psychiatry

Activation of nociceptin/orphanin FQ receptors inhibits contextual fear memory reconsolidation

(2017) Khaoula Rekik et al.   NEUROPHARMACOLOGY

Nociceptin Opioid Receptor (NOP) as a Therapeutic Target: Progress in Translation from Preclinical Research to Clinical Utility

(2016) Nurulain T. Zaveri   JOURNAL OF MEDICINAL CHEMISTRY

Designing bifunctional NOP receptor–mu opioid receptor ligands from NOP receptor-selective scaffolds. Part I.

(2013) Nurulain T. Zaveri et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Investigations into the involvement of NMDA mechanisms in recognition memory

(2013) E. Clea Warburton et al.   NEUROPHARMACOLOGY

The biology of Nociceptin/Orphanin FQ (N/OFQ) related to obesity, stress, anxiety, mood, and drug dependence

(2013) Jeffrey M. Witkin et al.   PHARMACOLOGY & THERAPEUTICS

Amygdala-Dependent Fear Is Regulated by Oprl1 in Mice and Humans with PTSD

(2013) R. Andero et al.   Science Translational Medicine

The Nociceptin/Orphanin FQ Receptor (NOP) as a Target for Drug Abuse Medications

(2011) Nurulain T. Zaveri   CURRENT TOPICS IN MEDICINAL CHEMISTRY

The nociceptin system and hippocampal cognition in mice A pharmacological and genetic analysis

(2009) Alexander Kuzmin et al.   BRAIN RESEARCH

Comparison of the Antinociceptive and Antirewarding Profiles of Novel Bifunctional Nociceptin Receptor/ -Opioid Receptor Ligands: Implications for Therapeutic Applications

(2009) L. Toll et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Activation of nociceptin opioid peptide (NOP) receptor impairs contextual fear learning in mice through glutamatergic mechanisms

(2009) Celia Goeldner et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Estrogen-dependent, sex-specific modulation of mustard oil-induced secondary thermal hyperalgesia by orphanin FQ in the rat

(2009) Jomo A. Claiborne et al.   NEUROSCIENCE LETTERS

Effects of nociceptin/orphanin FQ in the acquisition of contextual and tone fear conditioning in rats.

(2008) Raquel V. Fornari et al.   BEHAVIORAL NEUROSCIENCE

Blockade of NMDA receptors pre-training, but not post-training, impairs object displacement learning in the rat

(2008) Aoife E. Larkin et al.   BRAIN RESEARCH

Nociceptin Receptor Impairs Recognition Memory via Interaction with NMDA Receptor-Dependent Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Signaling in the Hippocampus

(2008) C. Goeldner et al.   JOURNAL OF NEUROSCIENCE

The nociceptin/orphanin FQ receptor: a target with broad therapeutic potential

(2008) David G. Lambert   NATURE REVIEWS DRUG DISCOVERY

How the brain remembers and forgets where things are: The neurocognition of object–location memory

(2008) A POSTMA et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS