SCFD1 in amyotrophic lateral sclerosis: reconciling a genetic association with in vivo functional analysis

Identifying novel genes for amyotrophic lateral sclerosis by integrating human brain proteomes with genome-wide association data

(2023) Xiao-Jing Gu et al.   JOURNAL OF NEUROLOGY

Loss of amyotrophic lateral sclerosis risk factor SCFD1 causes motor dysfunction in Drosophila

(2023) Rebecca Borg et al.   NEUROBIOLOGY OF AGING

Acetylation of SCFD1 regulates SNARE complex formation and autophagosome-lysosome fusion

(2022) Hong Huang et al.   Autophagy

TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A

(2022) Anna-Leigh Brown et al.   NATURE

TDP-43 represses cryptic exon inclusion in the FTD–ALS gene UNC13A

(2022) X. Rosa Ma et al.   NATURE

Genetic landscape of ALS in Malta based on a quinquennial analysis

(2022) Maia Farrugia Wismayer et al.   NEUROBIOLOGY OF AGING

Genetic analysis of amyotrophic lateral sclerosis identifies contributing pathways and cell types

(2021) Sara Saez-Atienzar et al.   Science Advances

Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

(2021) Wouter van Rheenen et al.   NATURE GENETICS

SM proteins Sly1 and Vps33 co-assemble with Sec17 and SNARE complexes to oppose SNARE disassembly by Sec18

(2014) Braden T Lobingier et al.   eLife

Autophagic substrate clearance requires activity of the syntaxin-5 SNARE complex

(2011) M. Renna et al.   JOURNAL OF CELL SCIENCE

Direct interaction between the COG complex and the SM protein, Sly1, is required for Golgi SNARE pairing

(2009) Orly Laufman et al.   EMBO JOURNAL