KU0063794, a Dual mTORC1 and mTORC2 Inhibitor, Reduces Neural Tissue Damage and Locomotor Impairment After Spinal Cord Injury in Mice

Cellular and Molecular Connections between Autophagy and Inflammation

(2015) Pierre Lapaquette et al.   MEDIATORS OF INFLAMMATION

Where is mTOR and what is it doing there?

(2014) Charles Betz et al.   JOURNAL OF CELL BIOLOGY

Potent Dual Inhibitors of TORC1 and TORC2 Complexes (KU-0063794 and KU-0068650) Demonstrate In Vitro and Ex Vivo Anti-Keloid Scar Activity

(2013) Farhatullah Syed et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Molecular evidence for the involvement of PPAR-δ and PPAR-γ in anti-inflammatory and neuroprotective activities of palmitoylethanolamide after spinal cord trauma

(2013) Irene Paterniti et al.   Journal of Neuroinflammation

A Comparison of Ku0063794, a Dual mTORC1 and mTORC2 Inhibitor, and Temsirolimus in Preclinical Renal Cell Carcinoma Models

(2013) Hao Zhang et al.   PLoS One

The role of mTOR signaling pathway in spinal cord injury

(2012) Haruo Kanno et al.   CELL CYCLE

Multifaceted effects of rapamycin on functional recovery after spinal cord injury in rats through autophagy promotion, anti-inflammation, and neuroprotection

(2012) Hsien-Chih Chen et al.   JOURNAL OF SURGICAL RESEARCH

GW0742, a High-Affinity PPAR-δ Agonist, Mediates Protection in an Organotypic Model of Spinal Cord Damage

(2011) Emanuela Esposito et al.   SPINE

Mammalian Target of Rapamycin (mTOR): Conducting the Cellular Signaling Symphony

(2010) Kathryn G. Foster et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of innate immune responses by autophagy-related proteins

(2010) Tatsuya Saitoh et al.   JOURNAL OF CELL BIOLOGY

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

Targeting mTOR: prospects for mTOR complex 2 inhibitors in cancer therapy

(2010) C A Sparks et al.   ONCOGENE

Anti-TNF therapy in the injured spinal cord

(2010) Emanuela Esposito et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Ku-0063794 is a specific inhibitor of the mammalian target of rapamycin (mTOR)

(2009) Juan M. García-Martínez et al.   BIOCHEMICAL JOURNAL

Common corruption of the mTOR signaling network in human tumors

(2009) S Menon et al.   ONCOGENE

Spinal cord injury: plasticity, regeneration and the challenge of translational drug development

(2008) Armin Blesch et al.   TRENDS IN NEUROSCIENCES