Expression of the Parkinson’s Disease-Associated Gene Alpha-Synuclein is Regulated by the Neuronal Cell Fate Determinant TRIM32

P73 and age-related diseases: is there any link with Parkinson Disease?

(2016) Francesca Grespi et al.   Aging-US

Olfactory dysfunction predicts early transition to a Lewy body disease in idiopathic RBD

(2015) P. Mahlknecht et al.   NEUROLOGY

The RNA helicase DDX6 regulates cell-fate specification in neural stem cells via miRNAs

(2015) Sarah Nicklas et al.   NUCLEIC ACIDS RESEARCH

The neural stem cell fate determinant TRIM32 regulates complex behavioral traits

(2015) Anna-Lena Hillje et al.   Frontiers in Cellular Neuroscience

TRIM32 modulates pluripotency entry and exit by directly regulating Oct4 stability

(2015) Lamia’a Bahnassawy et al.   Scientific Reports

Olfactory Dysfunction and Neurotransmitter Disturbance in Olfactory Bulb of Transgenic Mice Expressing Human A53T Mutant α-Synuclein

(2015) Sufang Zhang et al.   PLoS One

E3 ubiquitin ligase TRIM32 negatively regulates tumor suppressor p53 to promote tumorigenesis

(2014) Ju Liu et al.   CELL DEATH AND DIFFERENTIATION

Neural stem cells in Parkinson’s disease: a role for neurogenesis defects in onset and progression

(2014) Jaclyn Nicole Le Grand et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Deletion of TRIM32 protects mice from anxiety- and depression-like behaviors under mild stress

(2014) Chun-Sheng Ruan et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Disruption of the ASTN2/TRIM32 locus at 9q33.1 is a risk factor in males for autism spectrum disorders, ADHD and other neurodevelopmental phenotypes

(2014) A. C. Lionel et al.   HUMAN MOLECULAR GENETICS

Parkinson's disease correlates with promoter methylation in the α-synuclein gene

(2014) Lasse Pihlstrøm et al.   MOVEMENT DISORDERS

Epilepsy associated with autism and attention deficit hyperactivity disorder: Is there a genetic link?

(2013) Adriana Lo-Castro et al.   BRAIN & DEVELOPMENT

Endogenous alpha-synuclein influences the number of dopaminergic neurons in mouse substantia nigra

(2013) Pablo Garcia-Reitboeck et al.   EXPERIMENTAL NEUROLOGY

Methylation of α-synuclein and leucine-rich repeat kinase 2 in leukocyte DNA of Parkinson's disease patients

(2013) Yu-yan Tan et al.   PARKINSONISM & RELATED DISORDERS

Regulatory feedback loop between TP73 and TRIM32

(2013) L Gonzalez-Cano et al.   Cell Death & Disease

TRIM32-dependent transcription in adult neural progenitor cells regulates neuronal differentiation

(2013) A-L Hillje et al.   Cell Death & Disease

Adult neurogenesis in Parkinson’s disease

(2012) Franz Marxreiter et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

α-Synuclein Induces Alterations in Adult Neurogenesis in Parkinson Disease Models via p53-mediated Repression of Notch1

(2012) Paula Desplats et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TRIM32 Regulates Skeletal Muscle Stem Cell Differentiation and Is Necessary for Normal Adult Muscle Regeneration

(2012) Sarah Nicklas et al.   PLoS One

Parkinson's Disease: Genetics and Pathogenesis

(2011) Joshua M. Shulman et al.   Annual Review of Pathology-Mechanisms of Disease

TRIM32 Protein Sensitizes Cells to Tumor Necrosis Factor (TNFα)-induced Apoptosis via Its RING Domain-dependent E3 Ligase Activity against X-linked Inhibitor of Apoptosis (XIAP)

(2011) Yeung Sook Ryu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autosomal dominant Parkinson's disease

(2011) Christina Sundal et al.   PARKINSONISM & RELATED DISORDERS

Neural Stem Cells Maintain Their Stemness Through Protein Kinase C ζ Mediated Inhibition of TRIM32

(2011) Anna-Lena Hillje et al.   STEM CELLS

Genetic etiology of Parkinson disease associated with mutations in the SNCA, PARK2, PINK1, PARK7, and LRRK2 genes: a mutation update

(2010) Karen Nuytemans et al.   HUMAN MUTATION

Ectopic expression of α-synuclein affects the migration of neural stem cells in mouse subventricular zone

(2010) Momo Tani et al.   JOURNAL OF NEUROCHEMISTRY

Methylation Regulates Alpha-Synuclein Expression and Is Decreased in Parkinson's Disease Patients' Brains

(2010) A. Jowaed et al.   JOURNAL OF NEUROSCIENCE

Is adult neurogenesis essential for olfaction?

(2010) Françoise Lazarini et al.   TRENDS IN NEUROSCIENCES

p73 deficiency results in impaired self renewal and premature neuronal differentiation of mouse neural progenitors independently of p53

(2010) L Gonzalez-Cano et al.   Cell Death & Disease

Disruption of Adult Neurogenesis in the Olfactory Bulb Affects Social Interaction but not Maternal Behavior

(2010) Claudia E. Feierstein et al.   Frontiers in Behavioral Neuroscience

The TRIM-NHL Protein TRIM32 Activates MicroRNAs and Prevents Self-Renewal in Mouse Neural Progenitors

(2009) Jens C. Schwamborn et al.   CELL

Molecular pathogenesis of Parkinson disease: insights from genetic studies

(2009) Thomas Gasser   EXPERT REVIEWS IN MOLECULAR MEDICINE

Expansion of the Parkinson disease-associated SNCA- Rep1 allele upregulates human α-synuclein in transgenic mouse brain

(2009) Kenneth D. Cronin et al.   HUMAN MOLECULAR GENETICS

Functional dissection of the α-synuclein promoter: transcriptional regulation by ZSCAN21 and ZNF219

(2009) Richard Lee Clough et al.   JOURNAL OF NEUROCHEMISTRY

Tripartite Motif Protein 32 Facilitates Cell Growth and Migration via Degradation of Abl-Interactor 2

(2008) S. Kano et al.   CANCER RESEARCH

 -Synuclein Alters Notch-1 Expression and Neurogenesis in Mouse Embryonic Stem Cells and in the Hippocampus of Transgenic Mice

(2008) L. Crews et al.   JOURNAL OF NEUROSCIENCE

Nurr1 transcriptionally regulates the expression of ??-synuclein

(2008) Yan Xiang Yang et al.   NEUROREPORT

GATA transcription factors directly regulate the Parkinson's disease-linked gene  -synuclein

(2008) C. R. Scherzer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA