Rapamycin Effectively Impedes Melamine-Induced Impairments of Cognition and Synaptic Plasticity in Wistar Rats

Direct contact with particulate matter increases oxidative stress in different brain structures

(2015) Lucas Sagrillo Fagundes et al.   INHALATION TOXICOLOGY

Hydrogen Sulfide Prevents Synaptic Plasticity from VD-Induced Damage via Akt/GSK-3β Pathway and Notch Signaling Pathway in Rats

(2015) Chunhua Liu et al.   MOLECULAR NEUROBIOLOGY

Autophagy Alleviates Melamine-Induced Cell Death in PC12 Cells Via Decreasing ROS Level

(2015) Hui Wang et al.   MOLECULAR NEUROBIOLOGY

Unfolded Protein Response and Macroautophagy in Alzheimer’s, Parkinson’s and Prion Diseases

(2015) Irina Milisav et al.   MOLECULES

Antidepressant-like effects and possible mechanisms of amantadine on cognitive and synaptic deficits in a rat model of chronic stress

(2015) Mei Yu et al.   STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS

Regulation of mitophagy in ischemic brain injury

(2015) Yang Yuan et al.   Neuroscience Bulletin

Autophagy in the physiology and pathology of the central nervous system

(2014) V Nikoletopoulou et al.   CELL DEATH AND DIFFERENTIATION

Rapamycin: One Drug, Many Effects

(2014) Jing Li et al.   Cell Metabolism

Oxidative Stress and Its Significant Roles in Neurodegenerative Diseases and Cancer

(2014) Raynoo Thanan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Genetic Reduction of Mammalian Target of Rapamycin Ameliorates Alzheimer's Disease-Like Cognitive and Pathological Deficits by Restoring Hippocampal Gene Expression Signature

(2014) A. Caccamo et al.   JOURNAL OF NEUROSCIENCE

Loss of mTOR-Dependent Macroautophagy Causes Autistic-like Synaptic Pruning Deficits

(2014) Guomei Tang et al.   NEURON

The Neurology of mTOR

(2014) Jonathan O. Lipton et al.   NEURON

Vitamins C and E reverse melamine-induced deficits in spatial cognition and hippocampal synaptic plasticity in rats

(2014) Lei An et al.   NEUROTOXICOLOGY

Huntingtin promotes mTORC1 signaling in the pathogenesis of Huntington's disease

(2014) W. M. Pryor et al.   Science Signaling

Autophagy and hippocampal neuronal injury

(2014) Lulu Li et al.   Sleep and Breathing

Role of autophagy in prion protein-induced neurodegenerative diseases

(2013) H. Yao et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Reversible effects of vitamins C and E combination on oxidative stress-induced apoptosis in melamine-treated PC12 cells

(2013) L. An et al.   FREE RADICAL RESEARCH

Nicotine-induced impairments of spatial cognition and long-term potentiation in adolescent male rats

(2013) G Han et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Enhanced Brain Delivery of Deferasirox–Lactoferrin Conjugates for Iron Chelation Therapy in Neurodegenerative Disorders: In Vitro and in Vivo Studies

(2013) Golnaz Kamalinia et al.   MOLECULAR PHARMACEUTICS

Imbalanced Synaptic Plasticity Induced Spatial Cognition Impairment in Male Offspring Rats Treated with Chronic Prenatal Ethanol Exposure

(2012) Lei An et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Malin knockout mice support a primary role of autophagy in the pathogenesis of Lafora disease

(2012) Erwin Knecht et al.   Autophagy

Switching off LTP: mGlu and NMDA Receptor-Dependent Novelty Exploration-Induced Depotentiation in the Rat Hippocampus

(2012) Y. Qi et al.   CEREBRAL CORTEX

Targeted treatment trials for tuberous sclerosis and autism: no longer a dream

(2012) Mustafa Sahin   CURRENT OPINION IN NEUROBIOLOGY

Reactive oxygen species regulation of autophagy in cancer: Implications for cancer treatment

(2012) Lin Li et al.   FREE RADICAL BIOLOGY AND MEDICINE

Melamine induced spatial cognitive deficits associated with impairments of hippocampal long-term depression and cholinergic system in Wistar rats

(2012) Lei An et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Melamine induced cognitive impairment associated with oxidative damage in rat's hippocampus

(2012) Lei An et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

Cytoprotective effect of trolox against oxidative damage and apoptosis in the NRK-52e cells induced by melamine

(2011) Chengzhi Guo et al.   CELL BIOLOGY INTERNATIONAL

Efficacy and Safety of Sirolimus in Lymphangioleiomyomatosis

(2011) Francis X. McCormack et al.   NEW ENGLAND JOURNAL OF MEDICINE

Melamine impairs spatial cognition and hippocampal synaptic plasticity by presynaptic inhibition of glutamatergic transmission in infant rats

(2011) Jiajia Yang et al.   TOXICOLOGY

Insight into potential toxicity mechanisms of melamine: An in silico study

(2011) Chao Ma et al.   TOXICOLOGY

The effect of exogenous melamine on rat hippocampal neurons

(2011) Yan Wang et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

Cognitive deficits induced by melamine in rats

(2011) Lei An et al.   TOXICOLOGY LETTERS

Induction of Apoptosis by Melamine in Differentiated PC12 Cells

(2010) Yang-guang Han et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Molecular Interplay between Mammalian Target of Rapamycin (mTOR), Amyloid-β, and Tau

(2010) Antonella Caccamo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloid-Independent Mechanisms in Alzheimer's Disease Pathogenesis

(2010) S. W. Pimplikar et al.   JOURNAL OF NEUROSCIENCE

Autophagy: cellular and molecular mechanisms

(2010) Danielle Glick et al.   JOURNAL OF PATHOLOGY

Reversal of plasticity-like effects in the human motor cortex

(2010) Ying-Zu Huang et al.   JOURNAL OF PHYSIOLOGY-LONDON

The toxic influence of paraquat on hippocampus of mice: Involvement of oxidative stress

(2010) Qing Chen et al.   NEUROTOXICOLOGY

Action potential changes associated with impairment of functional properties of sodium channels in hippocampal neurons induced by melamine

(2010) Jia-Jia Yang et al.   TOXICOLOGY LETTERS

Determination of melamine in rat plasma, liver, kidney, spleen, bladder and brain by liquid chromatography–tandem mass spectrometry

(2009) Yu-Tse Wu et al.   JOURNAL OF CHROMATOGRAPHY A

Effect of melamine on potassium currents in rat hippocampal CA1 neurons

(2009) Jia-Jia Yang et al.   TOXICOLOGY IN VITRO

Regulation of Autophagy by Reactive Oxygen Species (ROS): Implications for Cancer Progression and Treatment

(2008) Meghan B. Azad et al.   ANTIOXIDANTS & REDOX SIGNALING

Rapamycin and mTOR-independent autophagy inducers ameliorate toxicity of polyglutamine-expanded huntingtin and related proteinopathies

(2008) S Sarkar et al.   CELL DEATH AND DIFFERENTIATION

Mechanism of alcohol-induced oxidative stress and neuronal injury

(2008) James Haorah et al.   FREE RADICAL BIOLOGY AND MEDICINE

Dopamine-modified α-synuclein blocks chaperone-mediated autophagy

(2008) Marta Martinez-Vicente et al.   JOURNAL OF CLINICAL INVESTIGATION

Reversal of learning deficits in a Tsc2 +/− mouse model of tuberous sclerosis

(2008) Dan Ehninger et al.   NATURE MEDICINE

Protective role of autophagy in neonatal hypoxia–ischemia induced brain injury

(2008) Silvia Carloni et al.   NEUROBIOLOGY OF DISEASE