Regioselective, catalytic 1,1-difluorination of enynes

Cyclopropene activation via I(I)/I(III) catalysis: Proof of principle and application in direct tetrafluorination

(2022) Stephanie Meyer et al.   TETRAHEDRON

3,3‐Difluoroallyl Sulfonium Salts: Practical and Bench‐Stable Reagents for Highly Regioselective gem ‐Difluoroallylations

(2022) Xiao‐Tian Feng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Skeletal Ring Contractions via I(I)/I(III) Catalysis: Stereoselective Synthesis of cis-α,α-Difluorocyclopropanes

(2022) Keith Livingstone et al.   ACS Catalysis

Trifluorinated Tetralins via I(I)/I(III)‐Catalysed Ring Expansion: Programming Conformation by [CH 2 CH 2 ] → [CF 2 CHF] Isosterism

(2021) Jessica Neufeld et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Arene Amination Instead of Fluorination: Substitution Pattern Governs the Reactivity of Dialkoxybenzenes with Selectfluor

(2021) Joseph N. Capilato et al.   JOURNAL OF ORGANIC CHEMISTRY

Electrophilic Fluorination of Alkenes via Bora‐Wagner–Meerwein Rearrangement. Access to β‐Difluoroalkyl Boronates

(2021) Qiang Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Contribution of Organofluorine Compounds to Pharmaceuticals

(2020) Munenori Inoue et al.   ACS Omega

Catalytic Enantioselective Synthesis of Difluorinated Alkyl Bromides

(2020) Mark D. Levin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Alkene Difunctionalization Using Hypervalent Iodine Reagents: Progress and Developments in the Past Ten Years

(2019) Lee et al.   MOLECULES

Enantioselective Copper(I)/Chiral Phosphoric Acid Catalyzed Intramolecular Amination of Allylic and Benzylic C−H Bonds

(2019) Liu Ye et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Hypervalent Iodines: Active Players in Asymmetric Synthesis

(2019) Alejandro Parra   CHEMICAL REVIEWS

Synthesis of β-Difluoroalkyl Azides via Elusive 1,2-Azide Migration

(2019) Yongquan Ning et al.   Chem

Informing Molecular Design by Stereoelectronic Theory: The Fluorine Gauche Effect in Catalysis

(2018) Marialuisa Aufiero et al.   ACCOUNTS OF CHEMICAL RESEARCH

Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design

(2018) Nicholas A. Meanwell   JOURNAL OF MEDICINAL CHEMISTRY

Enantioselective, Catalytic Vicinal Difluorination of Alkenes

(2018) Felix Scheidt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fluorine as a Traceless Directing Group for the Regiodivergent Synthesis of Indoles and Tryptophans

(2018) Anna Andries-Ulmer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

gem -Difluorination of Alkenyl N -methyliminodiacetyl Boronates: Synthesis of α- and β-Difluorinated Alkylborons

(2018) Wen-Xin Lv et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Difluorination of Functionalized Aromatic Olefins Using Hypervalent Iodine/HF Reagents

(2018) Tsugio Kitamura et al.   JOURNAL OF ORGANIC CHEMISTRY

Mechanism and Origins of Chemo- and Stereoselectivities of Aryl Iodide-Catalyzed Asymmetric Difluorinations of β-Substituted Styrenes

(2018) Biying Zhou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Geminal Difluorination of Styrenes for the Construction of Fluorine-rich Bioisosteres

(2018) Felix Scheidt et al.   ORGANIC LETTERS

Geminal difluorination of α,α’- disubstituted styrenes using fluoro-benziodoxole reagent. Migration aptitude of the α-substituents

(2017) Nadia O. Ilchenko et al.   JOURNAL OF FLUORINE CHEMISTRY

Deconstructing the Catalytic, Vicinal Difluorination of Alkenes: HF-Free Synthesis and Structural Study of p-TolIF2

(2017) Jérôme C. Sarie et al.   JOURNAL OF ORGANIC CHEMISTRY

CF2H, a Hydrogen Bond Donor

(2017) Chanan D. Sessler et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereoselective Halogenation in Natural Product Synthesis

(2016) Won-jin Chung et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Hypervalent iodine(iii) fluorinations of alkenes and diazo compounds: new opportunities in fluorination chemistry

(2016) Stefanie V. Kohlhepp et al.   CHEMICAL SOCIETY REVIEWS

Synthesis of Amides with Remote Stereocenters by Catalytic Asymmetric γ-Alkynylation of α,β-Unsaturated Amides

(2016) Zi-Xuan Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic, asymmetric difluorination of alkenes to generate difluoromethylated stereocenters

(2016) S. M. Banik et al.   SCIENCE

Highly selective oxidation of unsaturated hydrocarbons to carbonyl compounds by two-phase catalysis

(2016) Chun Mi et al.   TETRAHEDRON

Function through Synthesis-Informed Design

(2015) Paul A. Wender et al.   ACCOUNTS OF CHEMICAL RESEARCH

A recent survey of naturally occurring organohalogen compounds

(2015) Gordon W. Gribble   Environmental Chemistry

Synthesis of selectively fluorinated cyclohexanes: The observation of phenonium rearrangements during deoxyfluorination reactions on cyclohexane rings with a vicinal phenyl substituent

(2015) Tetiana Bykova et al.   JOURNAL OF FLUORINE CHEMISTRY

Fluorination Patterning: A Study of Structural Motifs That Impact Physicochemical Properties of Relevance to Drug Discovery

(2015) Quentin A. Huchet et al.   JOURNAL OF MEDICINAL CHEMISTRY

Hypervalent Iodine-Mediated Fluorination of Styrene Derivatives: Stoichiometric and Catalytic Transformation to 2,2-Difluoroethylarenes

(2015) Tsugio Kitamura et al.   JOURNAL OF ORGANIC CHEMISTRY

Mild Silver-Mediated Geminal Difluorination of Styrenes Using an Air- and Moisture-Stable Fluoroiodane Reagent

(2014) Nadia O. Ilchenko et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Highlycis-Selective and Enantioselective Metal-Free Hydrogenation of 2,3-Disubstituted Quinoxalines

(2014) Zhenhua Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The difluoromethylene (CF2) group in aliphatic chains: Synthesis and conformational preference of palmitic acids and nonadecane containing CF2groups

(2014) Yi Wang et al.   Beilstein Journal of Organic Chemistry

Influence of the difluoromethylene group (CF2) on the conformation and properties of selected organic compounds

(2012) David O'Hagan et al.   PURE AND APPLIED CHEMISTRY

Fluorine Conformational Effects in Organocatalysis: An Emerging Strategy for Molecular Design

(2011) Lucie E. Zimmer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis at the molecular frontier

(2009) Paul A. Wender et al.   NATURE

Understanding organofluorine chemistry. An introduction to the C–F bond

(2007) David O'Hagan   CHEMICAL SOCIETY REVIEWS

Fluorine in medicinal chemistry

(2007) Sophie Purser et al.   CHEMICAL SOCIETY REVIEWS