Design and testing of a humanized porcine donor for xenotransplantation

First clinical‐grade porcine kidney xenotransplant using a human decedent model

(2022) Paige M. Porrett et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Results of Two Cases of Pig-to-Human Kidney Xenotransplantation

(2022) Robert A. Montgomery et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genetically Modified Porcine-to-Human Cardiac Xenotransplantation

(2022) Bartley P. Griffith et al.   NEW ENGLAND JOURNAL OF MEDICINE

Anti-C5 Antibody Tesidolumab Reduces Early Antibody-mediated Rejection and Prolongs Survival in Renal Xenotransplantation

(2021) Andrew B. Adams et al.   ANNALS OF SURGERY

Emergence and significance of carbohydrate-specific antibodies

(2020) Katharina Kappler et al.   GENES AND IMMUNITY

Loss of decay-accelerating factor triggers podocyte injury and glomerulosclerosis

(2020) Andrea Angeletti et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Old World Monkeys are less than ideal transplantation models for testing pig organs lacking three carbohydrate antigens (Triple-Knockout)

(2020) Takayuki Yamamoto et al.   Scientific Reports

SUCCESSFUL LONG-TERM TMA- AND REJECTION-FREE SURVIVAL OF A KIDNEY XENOGRAFT WITH TRIPLE XENOANTIGEN KNOCKOUT PLUS INSERTION OF MULTIPLE HUMAN TRANSGENES

(2020) David Ma et al.   TRANSPLANTATION

Long-Term Survival of Pig-to-Rhesus Macaque Renal Xenografts is Dependent on CD4 T cell Depletion

(2019) S C Kim et al.   AMERICAN JOURNAL OF TRANSPLANTATION

The pathology of solid organ xenotransplantation

(2019) Ivy A. Rosales et al.   Current Opinion in Organ Transplantation

Development and validation of an ultra-high performance liquid chromatography–tandem mass spectrometry method for the simultaneous determination of iohexol, p-aminohippuric acid and creatinine in porcine and broiler chicken plasma

(2019) Laura Dhondt et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Genetically modified pigs as donors of cells, tissues, and organs for xenotransplantation

(2019) Eckhard Wolf et al.   Animal Frontiers

Determination of complete sequence information of the human ABO blood group orthologous gene in pigs and breed difference in blood type frequencies

(2018) Min-Kyeung Choi et al.   GENE

A 2018 Reference Guide to the Banff Classification of Renal Allograft Pathology

(2018) Candice Roufosse et al.   TRANSPLANTATION

Transplantation tolerance through mixed chimerism: From allo to xeno

(2018) David H. Sachs   XENOTRANSPLANTATION

Growth hormone receptor-deficient pigs resemble the pathophysiology of human Laron syndrome and reveal altered activation of signaling cascades in the liver

(2018) Arne Hinrichs et al.   Molecular Metabolism

Perspectives on the Optimal Genetically-Engineered pig in 2018 for Initial Clinical Trials of Kidney or Heart Xenotransplantation

(2018) David K.C. Cooper et al.   TRANSPLANTATION

Inactivation of porcine endogenous retrovirus in pigs using CRISPR-Cas9

(2017) Dong Niu et al.   SCIENCE

TCR-stimulated changes in cell surface CD46 expression generate type 1 regulatory T cells

(2017) Siobhan Ni Choileain et al.   Science Signaling

Immunological and physiological observations in baboons with life-supporting genetically engineered pig kidney grafts

(2017) Hayato Iwase et al.   XENOTRANSPLANTATION

TCR-stimulated changes in cell surface CD46 expression generate type 1 regulatory T cells

(2017) Siobhan Ni Choileain et al.   Science Signaling

Genome-wide inactivation of porcine endogenous retroviruses (PERVs)

(2015) L. Yang et al.   SCIENCE

Evaluation of human and non-human primate antibody binding to pig cells lacking GGTA1/CMAH/β4GalNT2 genes

(2015) Jose L. Estrada et al.   XENOTRANSPLANTATION

Endothelial cell protein C receptor: a multiliganded and multifunctional receptor

(2014) L. V. Mohan Rao et al.   BLOOD

A universal cloning method based on yeast homologous recombination that is simple, efficient, and versatile

(2014) Tammy M. Joska et al.   JOURNAL OF MICROBIOLOGICAL METHODS

RNA-Guided Human Genome Engineering via Cas9

(2013) P. Mali et al.   SCIENCE

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

High Cleavage Efficiency of a 2A Peptide Derived from Porcine Teschovirus-1 in Human Cell Lines, Zebrafish and Mice

(2011) Jin Hee Kim et al.   PLoS One

Transgenic expression of human heme oxygenase-1 in pigs confers resistance against xenograft rejection during ex vivo perfusion of porcine kidneys

(2011) Björn Petersen et al.   XENOTRANSPLANTATION

Identification of New Carbohydrate and Membrane Protein Antigens in Cardiac Xenotransplantation

(2010) Guerard W. Byrne et al.   TRANSPLANTATION

Transgenic expression of the human A20 gene in cloned pigs provides protection against apoptotic and inflammatory stimuli

(2009) Marianne Oropeza et al.   XENOTRANSPLANTATION