Genetic preservation of SLC22A3 in the Admixed and Xhosa populations living in the Western Cape

Genetic variation in organic cation transporters and considerations in drug development

(2023) Manthena V. S. Varma   Expert Opinion on Drug Metabolism & Toxicology

Clinical Applications and the Roles of Transporters in Disposition, Tumor Targeting, and Tissue Toxicity of meta-Iodobenzylguanidine (mIBG)

(2022) Antonio J Lopez Quiñones et al.   DRUG METABOLISM AND DISPOSITION

Genetic risk factors for colorectal cancer in multiethnic Indonesians

(2021) Irawan Yusuf et al.   Scientific Reports

Oncogenic PITX2 facilitates tumor cell drug resistance by inverse regulation of hOCT3/SLC22A3 and ABC drug transporters in colon and kidney cancers

(2019) Wing-Kee Lee et al.   CANCER LETTERS

Upregulated SLC22A3 has a potential for improving survival of patients with head and neck squamous cell carcinoma receiving cisplatin treatment

(2017) Cheng-Ming Hsu et al.   Oncotarget

The association between the expression of solute carrier transporters and the prognosis of pancreatic cancer

(2013) Beatrice Mohelnikova-Duchonova et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Inhibition of organic cation transporter 2 and 3 may be involved in the mechanism of the antidepressant-like action of berberine

(2013) Siyuan Sun et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Interpreting noncoding genetic variation in complex traits and human disease

(2012) Lucas D Ward et al.   NATURE BIOTECHNOLOGY

Genetic and epigenetic regulation of the organic cation transporter 3, SLC22A3

(2012) L Chen et al.   PHARMACOGENOMICS JOURNAL

Evaluation of organic cation transporter 3 (SLC22A3) inhibition as a potential mechanism of antidepressant action

(2012) Hao-Jie Zhu et al.   PHARMACOLOGICAL RESEARCH

Genetic and functional analyses implicate the NUDT11, HNF1B, and SLC22A3 genes in prostate cancer pathogenesis

(2012) C. Grisanzio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Common variant in 6q26-q27 is associated with distal colon cancer in an Asian population

(2011) R. Cui et al.   GUT

Contribution of Organic Cation Transporter 3 to Cisplatin Cytotoxicity in Human Cervical Cancer Cells

(2011) Qing Li et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Ensembl 2012

(2011) P. Flicek et al.   NUCLEIC ACIDS RESEARCH

Using SIFT and PolyPhen to Predict Loss-of-Function and Gain-of-Function Mutations

(2010) Sarah E. Flanagan et al.   Genetic Testing and Molecular Biomarkers

Role of organic cation transporter 3 (SLC22A3) and its missense variants in the pharmacologic action of metformin

(2010) Ligong Chen et al.   Pharmacogenetics and Genomics

Transport of guanidine compounds by human organic cation transporters, hOCT1 and hOCT2

(2009) Naoko Kimura et al.   BIOCHEMICAL PHARMACOLOGY

Expression of Human Organic Cation Transporter 3 in Kidney Carcinoma Cell Lines Increases Chemosensitivity to Melphalan, Irinotecan, and Vincristine

(2009) Volodymyr Shnitsar et al.   CANCER RESEARCH

Expression of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) is affected by genetic factors and cholestasis in human liver

(2009) Anne T. Nies et al.   HEPATOLOGY

Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease

(2009) David-Alexandre Trégouët et al.   NATURE GENETICS

Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm

(2009) Prateek Kumar et al.   Nature Protocols

Interaction between polymorphisms in the OCT1 and MATE1 transporter and metformin response

(2009) Matthijs L. Becker et al.   Pharmacogenetics and Genomics

Genetic variation in the organic cation transporter 1 is associated with metformin response in patients with diabetes mellitus

(2009) M L Becker et al.   PHARMACOGENOMICS JOURNAL

Medical Management of Hyperglycemia in Type 2 Diabetes: A Consensus Algorithm for the Initiation and Adjustment of Therapy: A consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes

(2008) D. M. Nathan et al.   DIABETES CARE

Significance of Organic Cation Transporter 3 (SLC22A3) Expression for the Cytotoxic Effect of Oxaliplatin in Colorectal Cancer

(2008) S. Yokoo et al.   DRUG METABOLISM AND DISPOSITION

Multiple newly identified loci associated with prostate cancer susceptibility

(2008) Rosalind A Eeles et al.   NATURE GENETICS