CDK signaling via nonconventional CDK phosphorylation sites

An atlas of substrate specificities for the human serine/threonine kinome

(2023) Jared L. Johnson et al.   NATURE

Cyclin A and Cks1 promote kinase consensus switching to non-proline-directed CDK1 phosphorylation

(2023) Aymen al-Rawi et al.   Cell Reports

Structural basis of human separase regulation by securin and CDK1–cyclin B1

(2021) Jun Yu et al.   NATURE

Multisite phosphorylation by Cdk1 initiates delayed negative feedback to control mitotic transcription

(2021) Jonathan B. Asfaha et al.   CURRENT BIOLOGY

G 1 cyclin–Cdk promotes cell cycle entry through localized phosphorylation of RNA polymerase II

(2021) Mardo Kõivomägi et al.   SCIENCE

Cdk1 Controls Global Epigenetic Landscape in Embryonic Stem Cells

(2020) Wojciech Michowski et al.   MOLECULAR CELL

A new linear cyclin docking motif that mediates exclusively S‐phase CDK‐specific signaling

(2020) Ilona Faustova et al.   EMBO JOURNAL

How the cell cycle clock ticks

(2019) Mihkel Örd et al.   MOLECULAR BIOLOGY OF THE CELL

Cyclin-Specific Docking Mechanisms Reveal the Complexity of M-CDK Function in the Cell Cycle

(2019) Mihkel Örd et al.   MOLECULAR CELL

Cyclin D-Cdk4,6 Drives Cell-Cycle Progression via the Retinoblastoma Protein’s C-Terminal Helix

(2019) Benjamin R. Topacio et al.   MOLECULAR CELL

Multisite phosphorylation code of CDK

(2019) Mihkel Örd et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

CDK and MAPK Synergistically Regulate Signaling Dynamics via a Shared Multi-site Phosphorylation Region on the Scaffold Protein Ste5

(2018) María Victoria Repetto et al.   MOLECULAR CELL

Molecular basis of outer kinetochore assembly on CENP-T

(2016) Pim J Huis in 't Veld et al.   eLife

CDK1 structures reveal conserved and unique features of the essential cell cycle CDK

(2015) Nicholas R. Brown et al.   Nature Communications

Identification of non-Ser/Thr-Pro consensus motifs for Cdk1 and their roles in mitotic regulation of C2H2 zinc finger proteins and Ect2

(2015) Kazuhiro Suzuki et al.   Scientific Reports

Cks confers specificity to phosphorylation-dependent CDK signaling pathways

(2013) Denise A McGrath et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Multisite phosphorylation networks as signal processors for Cdk1

(2013) Mardo Kõivomägi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cyclin-Specific Docking Motifs Promote Phosphorylation of Yeast Signaling Proteins by G1/S Cdk Complexes

(2011) Samyabrata Bhaduri et al.   CURRENT BIOLOGY

Dynamics of Cdk1 Substrate Specificity during the Cell Cycle

(2011) Mardo Kõivomägi et al.   MOLECULAR CELL

Cascades of multisite phosphorylation control Sic1 destruction at the onset of S phase

(2011) Mardo Kõivomägi et al.   NATURE

Deciphering Protein Kinase Specificity Through Large-Scale Analysis of Yeast Phosphorylation Site Motifs

(2010) J. Mok et al.   Science Signaling

An overview of Cdk1-controlled targets and processes

(2010) Jorrit M Enserink et al.   Cell Division

Global Analysis of Cdk1 Substrate Phosphorylation Sites Provides Insights into Evolution

(2009) L. J. Holt et al.   SCIENCE

A quantitative atlas of mitotic phosphorylation

(2008) N. Dephoure et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA