An end-to-end platform for digital pathology using hyperspectral autofluorescence microscopy and deep learning based virtual histology

Deep learning-enabled virtual histological staining of biological samples

(2023) Bijie Bai et al.   Light-Science & Applications

Digital pathology with artificial intelligence analyses provides greater insights into treatment-induced fibrosis regression in NASH

(2022) Nikolai V. Naoumov et al.   JOURNAL OF HEPATOLOGY

A Machine Learning Approach Enables Quantitative Measurement of Liver Histology and Disease Monitoring in NASH

(2021) Amaro Taylor‐Weiner et al.   HEPATOLOGY

Cenicriviroc Treatment for Adults with Nonalcoholic Steatohepatitis and Fibrosis: Final Analysis of the Phase 2b CENTAUR Study

(2020) Vlad Ratziu et al.   HEPATOLOGY

Suboptimal reliability of liver biopsy evaluation has implications for randomized clinical trials

(2020) Beth A. Davison et al.   JOURNAL OF HEPATOLOGY

NAD(P)H fluorescence lifetime measurements in fixed biological tissues

(2019) Jenu V Chacko et al.   Methods and Applications in Fluorescence

High-Throughput, Machine Learning-based Quantification of Steatosis, Inflammation, Ballooning, and Fibrosis in Biopsies From Patients with Nonalcoholic Fatty Liver Disease

(2019) Roberta Forlano et al.   Clinical Gastroenterology and Hepatology

Deep learning enables pathologist-like scoring of NASH models

(2019) Fabian Heinemann et al.   Scientific Reports

Mapping absolute tissue endogenous fluorophore concentrations with chemometric wide-field fluorescence microscopy

(2017) Zhang Xu et al.   JOURNAL OF BIOMEDICAL OPTICS

Rapid intraoperative histology of unprocessed surgical specimens via fibre-laser-based stimulated Raman scattering microscopy

(2017) Daniel A. Orringer et al.   Nature Biomedical Engineering

Efficacy and safety study of cenicriviroc for the treatment of non-alcoholic steatohepatitis in adult subjects with liver fibrosis: CENTAUR Phase 2b study design

(2016) Scott Friedman et al.   Contemporary Clinical Trials

Global epidemiology of nonalcoholic fatty liver disease-Meta-analytic assessment of prevalence, incidence, and outcomes

(2016) Zobair M. Younossi et al.   HEPATOLOGY

Stain-free histopathology by programmable supercontinuum pulses

(2016) Haohua Tu et al.   Nature Photonics

Classification of malignant and benign tumors of the lung by infrared spectral histopathology (SHP)

(2015) Ali Akalin et al.   LABORATORY INVESTIGATION

Autofluorescence spectroscopy and imaging: a tool for biomedical research and diagnosis

(2014) A.C. Croce et al.   EUROPEAN JOURNAL OF HISTOCHEMISTRY

Assessment of breast pathologies using nonlinear microscopy

(2014) Y. K. Tao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid, Label-Free Detection of Brain Tumors with Stimulated Raman Scattering Microscopy

(2013) M. Ji et al.   Science Translational Medicine

Integrated Optical Coherence Tomography and Microscopy for Ex Vivo Multiscale Evaluation of Human Breast Tissues

(2010) C. Zhou et al.   CANCER RESEARCH