Does mouse embryo primordial germ cell activation start before implantation as suggested by single-cell transcriptomics dynamics?

Human primordial germ cell commitment in vitro associates with a unique PRDM14 expression profile

(2015) F. Sugawa et al.   EMBO JOURNAL

SC3-seq: a method for highly parallel and quantitative measurement of single-cell gene expression

(2015) Tomonori Nakamura et al.   NUCLEIC ACIDS RESEARCH

The role of Tcfap2c in tumorigenesis and cancer growth in an activated Neu model of mammary carcinogenesis

(2015) J M Park et al.   ONCOGENE

Hepatic serum- and glucocorticoid-regulated protein kinase 1 (SGK1) regulates insulin sensitivity in mice via extracellular-signal-regulated kinase 1/2 (ERK1/2)

(2014) Hao Liu et al.   BIOCHEMICAL JOURNAL

Klf2 Is an Essential Factor that Sustains Ground State Pluripotency

(2014) Jia-Chi Yeo et al.   Cell Stem Cell

Single-cell RNA-seq: advances and future challenges

(2014) Antoine-Emmanuel Saliba et al.   NUCLEIC ACIDS RESEARCH

Developmental plasticity, cell fate specification and morphogenesis in the early mouse embryo

(2014) I. Bedzhov et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Single-Cell RNA-Seq Reveals Dynamic, Random Monoallelic Gene Expression in Mammalian Cells

(2014) Q. Deng et al.   SCIENCE

MORC1 represses transposable elements in the mouse male germline

(2014) William A. Pastor et al.   Nature Communications

PRDM14 Ensures Naive Pluripotency through Dual Regulation of Signaling and Epigenetic Pathways in Mouse Embryonic Stem Cells

(2013) Masashi Yamaji et al.   Cell Stem Cell

Genetic Correction of a LRRK2 Mutation in Human iPSCs Links Parkinsonian Neurodegeneration to ERK-Dependent Changes in Gene Expression

(2013) Peter Reinhardt et al.   Cell Stem Cell

Plasticity in Dnmt3L-dependent and -independent modes of de novo methylation in the developing mouse embryo

(2013) M. Guenatri et al.   DEVELOPMENT

PRDM14 promotes active DNA demethylation through the Ten-eleven translocation (TET)-mediated base excision repair pathway in embryonic stem cells

(2013) N. Okashita et al.   DEVELOPMENT

Anatomy of a blastocyst: Cell behaviors driving cell fate choice and morphogenesis in the early mouse embryo

(2013) Nadine Schrode et al.   GENESIS

Disclosing the crosstalk among DNA methylation, transcription factors, and histone marks in human pluripotent cells through discovery of DNA methylation motifs

(2013) P.-L. Luu et al.   GENOME RESEARCH

Cell-to-cell expression variability followed by signal reinforcement progressively segregates early mouse lineages

(2013) Yusuke Ohnishi et al.   NATURE CELL BIOLOGY

Single-cell sequencing-based technologies will revolutionize whole-organism science

(2013) Ehud Shapiro et al.   NATURE REVIEWS GENETICS

Transcription Factor TFAP2C Regulates Major Programs Required for Murine Fetal Germ Cell Maintenance and Haploinsufficiency Predisposes to Teratomas in Male Mice

(2013) Jana Schemmer et al.   PLoS One

RNA-sequencing from single nuclei

(2013) R. V. Grindberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The transcriptomic architecture of mouse Sertoli cell clone embryos reveals temporal–spatial-specific reprogramming

(2013) Feng Cao et al.   REPRODUCTION

The differential response to Fgf signalling in cells internalized at different times influences lineage segregation in preimplantation mouse embryos

(2013) S. A. Morris et al.   Open Biology

Transcription factor AP-2  is a core regulator of tight junction biogenesis and cavity formation during mouse early embryogenesis

(2012) I. Choi et al.   DEVELOPMENT

A unique regulatory phase of DNA methylation in the early mammalian embryo

(2012) Zachary D. Smith et al.   NATURE

ERK1 and ERK2 regulate embryonic stem cell self-renewal through phosphorylation of Klf4

(2012) Myoung Ok Kim et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Comprehensive Human Transcription Factor Binding Site Map for Combinatory Binding Motifs Discovery

(2012) Arnoldo J. Müller-Molina et al.   PLoS One

Primordial Germ Cells in Mice

(2012) M. Saitou et al.   Cold Spring Harbor Perspectives in Biology

Microbial environments confound antibiotic efficacy

(2011) Henry H Lee et al.   Nature Chemical Biology

A role for PDGF signaling in expansion of the extra-embryonic endoderm lineage of the mouse blastocyst

(2010) J. Artus et al.   DEVELOPMENT

FGF signal-dependent segregation of primitive endoderm and epiblast in the mouse blastocyst

(2010) Y. Yamanaka et al.   DEVELOPMENT

The regulation of Dkk1 expression during embryonic development

(2010) Oliver Lieven et al.   DEVELOPMENTAL BIOLOGY

Sox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewal

(2010) K. K. Niakan et al.   GENES & DEVELOPMENT

Genetic evidence for Dnmt3a-dependent imprinting during oocyte growth obtained by conditional knockout withZp3-Cre and complete exclusion of Dnmt3b by chimera formation

(2010) Masahiro Kaneda et al.   GENES TO CELLS

Examination of transcriptional networks reveals an important role for TCFAP2C, SMARCA4, and EOMES in trophoblast stem cell maintenance

(2010) B. L. Kidder et al.   GENOME RESEARCH

Identification of genes specific to mouse primordial germ cells through dynamic global gene expression

(2010) Davood Sabour et al.   HUMAN MOLECULAR GENETICS

Effect of ICSI on gene expression and development of mouse preimplantation embryos

(2010) G. Giritharan et al.   HUMAN REPRODUCTION

The Transcription Factor TCFAP2C/AP-2  Cooperates with CDX2 To Maintain Trophectoderm Formation

(2010) P. Kuckenberg et al.   MOLECULAR AND CELLULAR BIOLOGY

AKAP-Lbc enhances cyclic AMP control of the ERK1/2 cascade

(2010) F. Donelson Smith et al.   NATURE CELL BIOLOGY

Targets and dynamics of promoter DNA methylation during early mouse development

(2010) Julie Borgel et al.   NATURE GENETICS

Origin and formation of the first two distinct cell types of the inner cell mass in the mouse embryo

(2010) S. A. Morris et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Collagen type IV and Perlecan exhibit dynamic localization in the Allantoic Core Domain, a putative stem cell niche in the murine allantois

(2009) Maria M. Mikedis et al.   DEVELOPMENTAL DYNAMICS

Trim43a, Trim43b, and Trim43c: Novel mouse genes expressed specifically in mouse preimplantation embryos

(2009) Ilaria Stanghellini et al.   GENE EXPRESSION PATTERNS

Critical function of Prdm14 for the establishment of the germ cell lineage in mice

(2008) Masashi Yamaji et al.   NATURE GENETICS

Nutrient Sensing by the Early Mouse Embryo: Hexosamine Biosynthesis and Glucose Signaling During Preimplantation Development1

(2007) Marie Pantaleon et al.   BIOLOGY OF REPRODUCTION