Integrated machine learning identifies epithelial cell marker genes for improving outcomes and immunotherapy in prostate cancer

Cancer statistics, 2023

(2023) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Mechanisms of Protein Trafficking and Quality Control in the Kidney and Beyond

(2023) Jillian L. Shaw et al.   Annual Review of Physiology

Multi-omics analysis reveals a macrophage-related marker gene signature for prognostic prediction, immune landscape, genomic heterogeneity, and drug choices in prostate cancer

(2023) Weian Zhu et al.   Frontiers in Immunology

Proteomic analysis of STEAP1 knockdown in human LNCaP prostate cancer cells

(2023) Sandra M. Rocha et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Prostate cancer immunotherapy

(2022) Iraklis Mitsogiannis et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Single-cell analysis of human primary prostate cancer reveals the heterogeneity of tumor-associated epithelial cell states

(2022) Hanbing Song et al.   Nature Communications

Pembrolizumab Plus Docetaxel and Prednisone in Patients with Metastatic Castration-resistant Prostate Cancer: Long-term Results from the Phase 1b/2 KEYNOTE-365 Cohort B Study

(2022) Evan Y. Yu et al.   EUROPEAN UROLOGY

Cancer-associated fibroblast-derived gene signatures predict radiotherapeutic survival in prostate cancer patients

(2022) Ran Zhang et al.   Journal of Translational Medicine

The established chemokine-related prognostic gene signature in prostate cancer: Implications for anti-androgen and immunotherapies

(2022) Lei Chen et al.   Frontiers in Immunology

Randomized phase II trial of sipuleucel-T with or without radium-223 in men with bone-metastatic castration-resistant prostate cancer

(2021) Catherine H. Marshall et al.   CLINICAL CANCER RESEARCH

Single-cell analysis reveals transcriptomic remodellings in distinct cell types that contribute to human prostate cancer progression

(2021) Sujun Chen et al.   NATURE CELL BIOLOGY

Immunotherapy and Immunotherapy Combinations in Metastatic Castration-Resistant Prostate Cancer

(2021) Dhruv Bansal et al.   Cancers

Clinical significance of STEAP1 extracellular vesicles in prostate cancer

(2021) Karan Khanna et al.   PROSTATE CANCER AND PROSTATIC DISEASES

Prostate cancer

(2021) Richard J. Rebello et al.   Nature Reviews Disease Primers

HJURP promotes proliferation in prostate cancer cells through increasing CDKN1A degradation via the GSK3β/JNK signaling pathway

(2021) Wenjie Lai et al.   Cell Death & Disease

Prostate Cancer Immunotherapy—Finally in From the Cold?

(2021) Karie D. Runcie et al.   Current Oncology Reports

Inherited TP53 Variants and Risk of Prostate Cancer

(2021) Kara N. Maxwell et al.   EUROPEAN UROLOGY

Turning up the heat on non-immunoreactive tumors: pyroptosis influences the tumor immune microenvironment in bladder cancer

(2021) Xingyu Chen et al.   ONCOGENE

Revisiting Immunotherapy: A Focus on Prostate Cancer

(2020) Ha-Ram Cha et al.   CANCER RESEARCH

Clinical application of immune checkpoints in targeted immunotherapy of prostate cancer

(2020) Sevda Jafari et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Prognostic and Predictive Molecular Biomarkers for Colorectal Cancer: Updates and Challenges

(2020) Koncina et al.   Cancers

The history and advances in cancer immunotherapy: understanding the characteristics of tumor-infiltrating immune cells and their therapeutic implications

(2020) Yuanyuan Zhang et al.   Cellular & Molecular Immunology

Dynamics of Cellular Plasticity in Prostate Cancer Progression

(2020) Ritika Tiwari et al.   Frontiers in Molecular Biosciences

GTSE1 promotes prostate cancer cell proliferation via the SP1/FOXM1 signaling pathway

(2020) Wenjie Lai et al.   LABORATORY INVESTIGATION

Molecular and pharmacological modulators of the tumor immune contexture revealed by deconvolution of RNA-seq data

(2019) Francesca Finotello et al.   Genome Medicine

Current Knowledge of the Potential Links between Inflammation and Prostate Cancer

(2019) Tommaso Cai et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Epithelial cells: liaisons of immunity

(2019) Samantha B Larsen et al.   CURRENT OPINION IN IMMUNOLOGY

Genomic Markers in Prostate Cancer Decision Making

(2018) Vito Cucchiara et al.   EUROPEAN UROLOGY

TNM clinical staging of prostate cancer: issues and solutions

(2018) Murali Varma et al.   BJU INTERNATIONAL

Prognostic Value of Biochemical Recurrence Following Treatment with Curative Intent for Prostate Cancer: A Systematic Review

(2018) Thomas Van den Broeck et al.   EUROPEAN UROLOGY

Cell plasticity in epithelial homeostasis and tumorigenesis

(2017) Julia Varga et al.   NATURE CELL BIOLOGY

GOLM1 promotes prostate cancer progression through activating PI3K-AKT-mTOR signaling

(2017) Guang Yan et al.   PROSTATE

Depletion of regulatory T cells by anti-ICOS antibody enhances anti-tumor immunity of tumor cell vaccine in prostate cancer

(2017) Lijun Mo et al.   VACCINE

Self-Normalized Detection of ANXA3 from Untreated Urine of Prostate Cancer Patients without Digital Rectal Examination

(2017) Minhong Jeun et al.   Advanced Healthcare Materials

Deletion of Interstitial Genes betweenTMPRSS2andERGPromotes Prostate Cancer Progression

(2016) Douglas E. Linn et al.   CANCER RESEARCH

Molecular and Genetic Properties of Tumors Associated with Local Immune Cytolytic Activity

(2015) Michael S. Rooney et al.   CELL

Machine Learning in Medicine

(2015) R. C. Deo   CIRCULATION

Barrier Epithelial Cells and the Control of Type 2 Immunity

(2015) Hamida Hammad et al.   IMMUNITY

Respiratory epithelial cells orchestrate pulmonary innate immunity

(2015) Jeffrey A Whitsett et al.   NATURE IMMUNOLOGY

Robust enumeration of cell subsets from tissue expression profiles

(2015) Aaron M Newman et al.   NATURE METHODS

Validation of proposed prostate cancer biomarkers with gene expression data: a long road to travel

(2014) Adriana Amaro et al.   CANCER AND METASTASIS REVIEWS

Copy Number Gain of hsa-miR-569 at 3q26.2 Leads to Loss of TP53INP1 and Aggressiveness of Epithelial Cancers

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Single luminal epithelial progenitors can generate prostate organoids in culture

(2014) Chee Wai Chua et al.   NATURE CELL BIOLOGY

Spatiotemporal Dynamics of Intratumoral Immune Cells Reveal the Immune Landscape in Human Cancer

(2013) Gabriela Bindea et al.   IMMUNITY

Immunotherapy and Immune Evasion in Prostate Cancer

(2013) Archana Thakur et al.   Cancers