Less is more: low expression of MT1-MMP is optimal to promote migration and tumourigenesis of breast cancer cells

Fibroblast Growth Factor Receptor-Dependent and -Independent Paracrine Signaling by Sunitinib-Resistant Renal Cell Carcinoma

(2016) Tram Anh Tran et al.   MOLECULAR AND CELLULAR BIOLOGY

Quantification of cancer cell extravasation in vivo

(2016) Yohan Kim et al.   Nature Protocols

High-Throughput Multiplexed Peptide-Centric Profiling Illustrates Both Substrate Cleavage Redundancy and Specificity in the MMP Family

(2015) Muskan Kukreja et al.   CHEMISTRY & BIOLOGY

The source of matrix-degrading enzymes in human cancer: Problems of research reproducibility and possible solutions

(2015) Daniel H. Madsen et al.   JOURNAL OF CELL BIOLOGY

ARF6–JIP3/4 regulate endosomal tubules for MT1-MMP exocytosis in cancer invasion

(2015) Valentina Marchesin et al.   JOURNAL OF CELL BIOLOGY

Open source software for quantification of cell migration, protrusions, and fluorescence intensities

(2015) David J. Barry et al.   JOURNAL OF CELL BIOLOGY

Reproducibility: Standardize antibodies used in research

(2015) Andrew Bradbury et al.   NATURE

p63/MT1-MMP axis is required for in situ to invasive transition in basal-like breast cancer

(2015) C Lodillinsky et al.   ONCOGENE

TIMP-2 Interaction with MT1-MMP Activates the AKT Pathway and Protects Tumor Cells from Apoptosis

(2015) Cristina Valacca et al.   PLoS One

The chick embryo chorioallantoic membrane as a model for tumor biology

(2014) Domenico Ribatti   EXPERIMENTAL CELL RESEARCH

Traversing the basement membrane in vivo: A diversity of strategies

(2014) Laura C. Kelley et al.   JOURNAL OF CELL BIOLOGY

Membrane-Type 1 Matrix Metalloproteinase Downregulates Fibroblast Growth Factor-2 Binding to the Cell Surface and Intracellular Signaling

(2014) Evelyne Tassone et al.   JOURNAL OF CELLULAR PHYSIOLOGY

A new transcriptional role for matrix metalloproteinase-12 in antiviral immunity

(2014) David J Marchant et al.   NATURE MEDICINE

Invadopodia Are Required for Cancer Cell Extravasation and Are a Therapeutic Target for Metastasis

(2014) Hon S. Leong et al.   Cell Reports

Quantification of Breast Cancer Cell Invasiveness Using a Three-dimensional (3D) Model

(2014) Donna Cvetković et al.   Jove-Journal of Visualized Experiments

ADAM12 redistributes and activates MMP-14, resulting in gelatin degradation, reduced apoptosis and increased tumor growth

(2013) R. Albrechtsen et al.   JOURNAL OF CELL SCIENCE

Analysis of the MMP-dependent and independent functions of tissue inhibitor of metalloproteinase-2 on the invasiveness of breast cancer cells

(2012) Logan A. Walsh et al.   Journal of Cell Communication and Signaling

Cancer Cell-Associated MT1-MMP Promotes Blood Vessel Invasion and Distant Metastasis in Triple-Negative Mammary Tumors

(2011) J. Y. Perentes et al.   CANCER RESEARCH

Phosphorylation of Membrane Type 1-Matrix Metalloproteinase (MT1-MMP) and Its Vesicle-associated Membrane Protein 7 (VAMP7)-dependent Trafficking Facilitate Cell Invasion and Migration

(2011) Karla C. Williams et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting the Warburg Effect That Arises in Tumor Cells Expressing Membrane Type-1 Matrix Metalloproteinase

(2011) Takeharu Sakamoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of Matrix Metalloproteinase 14 (MMP-14)-mediated Cancer Cell Migration

(2011) Kevin Zarrabi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Membrane Protease Regulates Energy Production in Macrophages by Activating Hypoxia-inducible Factor-1 via a Non-proteolytic Mechanism

(2010) Takeharu Sakamoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human 21T breast epithelial cell lines mimic breast cancer progression in vivo and in vitro and show stage-specific gene expression patterns

(2010) Lesley H Souter et al.   LABORATORY INVESTIGATION

Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs): Positive and negative regulators in tumor cell adhesion

(2010) Dimitra Bourboulia et al.   SEMINARS IN CANCER BIOLOGY

Proteolytic and non-proteolytic roles of membrane type-1 matrix metalloproteinase in malignancy

(2009) Alex Y. Strongin   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Correlation between MMPs and their inhibitors in breast cancer tumor tissue specimens and in cell lines with different metastatic potential

(2009) Rita CS Figueira et al.   BMC CANCER

Expression of matrix metalloproteinases (MMPs) in primary human breast cancer and breast cancer cell lines: New findings and review of the literature

(2009) Andrea Köhrmann et al.   BMC CANCER

Epigenetic Control of the Invasion-promoting MT1-MMP/MMP-2/TIMP-2 Axis in Cancer Cells

(2009) Andrei V. Chernov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Human Breast Cell Model of Preinvasive to Invasive Transition

(2008) A. Rizki et al.   CANCER RESEARCH

Novel Transcription Factor-Like Function of Human Matrix Metalloproteinase 3 Regulating the CTGF/CCN2 Gene

(2008) T. Eguchi et al.   MOLECULAR AND CELLULAR BIOLOGY

Molecular Basis of Metastasis

(2008) Anne C. Chiang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Unraveling the microenvironmental influences on the normal mammary gland and breast cancer

(2008) Britta Weigelt et al.   SEMINARS IN CANCER BIOLOGY

Breaching the basement membrane: who, when and how?

(2008) R. Grant Rowe et al.   TRENDS IN CELL BIOLOGY