A tyrosine-reactive irreversible inhibitor for glutathione S-transferase Pi (GSTP1)

Phosphorylation of GlutathioneS-Transferase P1 (GSTP1) by Epidermal Growth Factor Receptor (EGFR) Promotes Formation of the GSTP1-c-Jun N-terminal kinase (JNK) Complex and Suppresses JNK Downstream Signaling and Apoptosis in Brain Tumor Cells

(2015) Tatsunori Okamura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Investigating the Proteome Reactivity and Selectivity of Aryl Halides

(2014) D. Alexander Shannon et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Piperlongumine Induces Apoptosis and Synergizes with Cisplatin or Paclitaxel in Human Ovarian Cancer Cells

(2014) Li-Hua Gong et al.   Oxidative Medicine and Cellular Longevity

Regulation of epigenetic traits of the glutathione S-transferase P1 gene: from detoxification toward cancer prevention and diagnosis

(2014) Michael Schnekenburger et al.   Frontiers in Pharmacology

Chemical Proteomics with Sulfonyl Fluoride Probes Reveals Selective Labeling of Functional Tyrosines in Glutathione Transferases

(2013) Christian Gu et al.   CHEMISTRY & BIOLOGY

Identifying and Characterizing Binding Sites on the Irreversible Inhibition of Human Glutathione S-Transferase P1-1 by S-Thiocarbamoylation

(2012) Indalecio Quesada-Soriano et al.   CHEMBIOCHEM

Sulfonyl Fluoride Analogues as Activity-Based Probes for Serine Proteases

(2012) D. Alexander Shannon et al.   CHEMBIOCHEM

Phase 1 dose-ranging study of ezatiostat hydrochloride in combination with lenalidomide in patients with non-deletion (5q) low to intermediate-1 risk myelodysplastic syndrome (MDS)

(2012) Azra Raza et al.   Journal of Hematology & Oncology

The inhibition characteristics of human placental glutathione S-transferase-π by tricyclic antidepressants: amitriptyline and clomipramine

(2011) Ozlem Dalmizrak et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Glutathione transferases as mediators of signaling pathways involved in cell proliferation and cell death

(2010) E Laborde   CELL DEATH AND DIFFERENTIATION

Tyrosine 8 contributes to catalysis but is not required for activity of rat liver glutathione S-transferase, 1-1

(2010) Jibo Wang et al.   PROTEIN SCIENCE

Phase 1 multicenter dose-escalation study of ezatiostat hydrochloride (TLK199 tablets), a novel glutathione analog prodrug, in patients with myelodysplastic syndrome

(2009) A. Raza et al.   BLOOD