Cell biology of fat storage

A Secreted Slit2 Fragment Regulates Adipose Tissue Thermogenesis and Metabolic Function

(2016) Katrin J. Svensson et al.   Cell Metabolism

Mitochondrial ROS regulate thermogenic energy expenditure and sulfenylation of UCP1

(2016) Edward T. Chouchani et al.   NATURE

Mouse strains to study cold-inducible beige progenitors and beige adipocyte formation and function

(2016) Daniel C. Berry et al.   Nature Communications

Activated Type 2 Innate Lymphoid Cells Regulate Beige Fat Biogenesis

(2015) Min-Woo Lee et al.   CELL

Sympathetic Neuro-adipose Connections Mediate Leptin-Driven Lipolysis

(2015) Wenwen Zeng et al.   CELL

A Creatine-Driven Substrate Cycle Enhances Energy Expenditure and Thermogenesis in Beige Fat

(2015) Lawrence Kazak et al.   CELL

Immune Regulation of Metabolic Homeostasis in Health and Disease

(2015) Jonathan R. Brestoff et al.   CELL

Activation of Human Brown Adipose Tissue by a β3-Adrenergic Receptor Agonist

(2015) Aaron M. Cypess et al.   Cell Metabolism

Brown and Beige Fat: Physiological Roles beyond Heat Generation

(2015) Shingo Kajimura et al.   Cell Metabolism

Brown and Beige Fat: Molecular Parts of a Thermogenic Machine

(2015) Paul Cohen et al.   DIABETES

Eosinophils and Type 2 Cytokine Signaling in Macrophages Orchestrate Development of Functional Beige Fat

(2014) Yifu Qiu et al.   CELL

Meteorin-like Is a Hormone that Regulates Immune-Adipose Interactions to Increase Beige Fat Thermogenesis

(2014) Rajesh R. Rao et al.   CELL

Adipsin Is an Adipokine that Improves β Cell Function in Diabetes

(2014) James C. Lo et al.   CELL

What We Talk About When We Talk About Fat

(2014) Evan D. Rosen et al.   CELL

A Smooth Muscle-Like Origin for Beige Adipocytes

(2014) Jonathan Z. Long et al.   Cell Metabolism

Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity

(2014) Jonathan R. Brestoff et al.   NATURE

A Classical Brown Adipose Tissue mRNA Signature Partly Overlaps with Brite in the Supraclavicular Region of Adult Humans

(2013) Naja Zenius Jespersen et al.   Cell Metabolism

Dichotomous roles of leptin and adiponectin as enforcers against lipotoxicity during feast and famine

(2013) Roger H. Unger et al.   MOLECULAR BIOLOGY OF THE CELL

Evidence for two types of brown adipose tissue in humans

(2013) Martin E Lidell et al.   NATURE MEDICINE

An inhibitor of the protein kinases TBK1 and IKK-ɛ improves obesity-related metabolic dysfunctions in mice

(2013) Shannon M Reilly et al.   NATURE MEDICINE

Anatomical localization, gene expression profiling and functional characterization of adult human neck brown fat

(2013) Aaron M Cypess et al.   NATURE MEDICINE

Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human

(2012) Jun Wu et al.   CELL

Dietary obesity-associated Hif1  activation in adipocytes restricts fatty acid oxidation and energy expenditure via suppression of the Sirt2-NAD+ system

(2012) J. Krishnan et al.   GENES & DEVELOPMENT

FGF21 regulates PGC-1  and browning of white adipose tissues in adaptive thermogenesis

(2012) f. M. Fisher et al.   GENES & DEVELOPMENT

Cardiac natriuretic peptides act via p38 MAPK to induce the brown fat thermogenic program in mouse and human adipocytes

(2012) Marica Bordicchia et al.   JOURNAL OF CLINICAL INVESTIGATION

Selective Inhibition of Hypoxia-Inducible Factor 1  Ameliorates Adipose Tissue Dysfunction

(2012) K. Sun et al.   MOLECULAR AND CELLULAR BIOLOGY

PPAR-γ is a major driver of the accumulation and phenotype of adipose tissue Treg cells

(2012) Daniela Cipolletta et al.   NATURE

Immunological complications of obesity

(2012) Thirumala-Devi Kanneganti et al.   NATURE IMMUNOLOGY

Human BAT Possesses Molecular Signatures That Resemble Beige/Brite Cells

(2012) Louis Z. Sharp et al.   PLoS One

Disruption of Hypoxia-Inducible Factor 1 in Adipocytes Improves Insulin Sensitivity and Decreases Adiposity in High-Fat Diet-Fed Mice

(2011) C. Jiang et al.   DIABETES

Lipodystrophies: Genetic and Acquired Body Fat Disorders

(2011) Abhimanyu Garg   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis

(2011) Khoa D. Nguyen et al.   NATURE

Inducible lineage tracing of Pax7-descendant cells reveals embryonic origin of adult satellite cells

(2010) Christoph Lepper et al.   GENESIS

Sympathetic and sensory innervation of brown adipose tissue

(2010) T J Bartness et al.   INTERNATIONAL JOURNAL OF OBESITY

Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice

(2010) Patrick Seale et al.   JOURNAL OF CLINICAL INVESTIGATION

Sensory and sympathetic nervous system control of white adipose tissue lipolysis

(2009) Timothy J. Bartness et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters

(2009) Markus Feuerer et al.   NATURE MEDICINE

Functional Brown Adipose Tissue in Healthy Adults

(2009) Kirsi A. Virtanen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cold-Activated Brown Adipose Tissue in Healthy Men

(2009) Wouter D. van Marken Lichtenbelt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification and Importance of Brown Adipose Tissue in Adult Humans

(2009) Aaron M. Cypess et al.   NEW ENGLAND JOURNAL OF MEDICINE

PRDM16 controls a brown fat/skeletal muscle switch

(2008) Patrick Seale et al.   NATURE

New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure

(2008) Yu-Hua Tseng et al.   NATURE