Matrix effects demystified: Strategies for resolving challenges in analytical separations of complex samples

New Challenges in (Bio)Analytical Sample Treatment Procedures for Clinical Applications

(2023) Valentina Greco et al.   Separations

Investigation of the adsorption/desorption mechanism of perfluoroalkyl substances on HLB-WAX extraction phases for microextraction

(2023) Aghogho A. Olomukoro et al.   ANALYTICA CHIMICA ACTA

Graphene-Type Materials for the Dispersive Solid-Phase Extraction Step in the QuEChERS Method for the Extraction of Brominated Flame Retardants from Capsicum Cultivars

(2023) Virgínia Cruz Fernandes et al.   Journal of Agricultural and Food Chemistry

A high‐throughput liquid chromatography‐tandem mass spectrometry method for simultaneous determination of direct oral anticoagulants in human plasma

(2023) Nela Žideková et al.   JOURNAL OF SEPARATION SCIENCE

Matrix Effects in GC–MS Profiling of Common Metabolites after Trimethylsilyl Derivatization

(2023) Elena Tarakhovskaya et al.   MOLECULES

Bioanalytical Methods and Strategic Perspectives Addressing the Rising Complexity of Novel Bioconjugates and Delivery Routes for Biotherapeutics

(2022) Ruipeng Mu et al.   BIODRUGS

Current development of bioanalytical sample preparation techniques in pharmaceuticals

(2022) Rahul G. Ingle et al.   Journal of Pharmaceutical Analysis

QuEChERS-based analytical methods developed for LC-MS/MS multiresidue determination of pesticides in representative crop fatty matrices: Olives and sunflower seeds

(2022) Manuel García-Vara et al.   FOOD CHEMISTRY

Recent advancements in techniques for analyzing modern, atypical antidepressants in complex biological matrices and their application in biomedical studies

(2022) Anna Roszkowska et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Direct immersion thin film solid phase microextraction of polychlorinated n-alkanes in cod liver oil

(2021) Dominika Gruszecka et al.   FOOD CHEMISTRY

Assessment of solid phase microextraction as a sample preparation tool for untargeted analysis of brain tissue using liquid chromatography-mass spectrometry

(2021) Nathaly Reyes-Garcés et al.   JOURNAL OF CHROMATOGRAPHY A

One extraction tool for in vitro-in vivo extrapolation? SPME-based metabolomics of in vitro 2 2D, 3D, in vivo mouse melanoma models

(2021) Karol Jaroch et al.   Journal of Pharmaceutical Analysis

Correction of Matrix Effects for Reliable Non-target Screening LC–ESI–MS Analysis of Wastewater

(2021) Selina Tisler et al.   ANALYTICAL CHEMISTRY

In vivo analytical techniques facilitated by contemporary materials

(2021) Nipunika H. Godage et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Evaluation of matrix effects and extraction efficiencies of LC-MS/MS methods as the essential part for proper validation of multiclass contaminants in complex feed

(2020) David Steiner et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Compensate for or Minimize Matrix Effects? Strategies for Overcoming Matrix Effects in Liquid Chromatography-Mass Spectrometry Technique: A Tutorial Review

(2020) Manuela Cortese et al.   MOLECULES

Applications of single-drop microextraction in analytical chemistry: A review

(2020) Suresh Kumar Kailasa et al.   Trends in Environmental Analytical Chemistry

A critical outlook on recent developments and applications of matrix compatible coatings for Solid Phase Microextraction

(2019) Nipunika H. Godage et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Quantitative issues related to the headspace-SPME-GC/MS analysis of volatile compounds in wines: The case of Maresco sparkling wine

(2019) Maria Tufariello et al.   LWT-FOOD SCIENCE AND TECHNOLOGY

A Critical Review on Regulatory Sample Preparation Methods: Validating Solid-Phase Microextraction Techniques

(2019) Maryam Lashgari et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Effective removal matrix interferences by a modified QuEChERS based on the molecularly imprinted polymers for determination of 84 polychlorinated biphenyls and organochlorine pesticides in shellfish samples

(2019) Wei Li et al.   JOURNAL OF HAZARDOUS MATERIALS

Standard addition with internal standardisation as an alternative to using stable isotope labelled internal standards to correct for matrix effects—Comparison and validation using liquid chromatography-​tandem mass spectrometric assay of vitamin D

(2018) Amitha K. Hewavitharana et al.   JOURNAL OF CHROMATOGRAPHY A

Exploring matrix effects and quantifying organic additives in hydraulic fracturing associated fluids using liquid chromatography electrospray ionization mass spectrometry

(2018) Marika Nell et al.   Environmental Science-Processes & Impacts

Single-Drop Microextraction

(2018) Sheng Tang et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Three approaches to minimize matrix effects in residue analysis of multiclass pesticides in dried complex matrices using gas chromatography tandem mass spectrometry

(2018) Ewa Rutkowska et al.   FOOD CHEMISTRY

Compensation of matrix effects in gas chromatography–mass spectrometry analysis of pesticides using a combination of matrix matching and multiple isotopically labeled internal standards

(2017) Tomoyuki Tsuchiyama et al.   JOURNAL OF CHROMATOGRAPHY A

Assessing Environmental Exposure to β-N-Methylamino-l-Alanine (BMAA) in Complex Sample Matrices: a Comparison of the Three Most Popular LC-MS/MS Methods

(2017) Teesha C. Baker et al.   NEUROTOXICITY RESEARCH

Chitosan patterning on titanium implants

(2017) Eduardo Gilabert-Chirivella et al.   PROGRESS IN ORGANIC COATINGS

Cyclohexylamine as extraction solvent and chelating agent in extraction and preconcentration of some heavy metals in aqueous samples based on heat-induced homogeneous liquid-liquid extraction

(2017) Saeed Mohammad Sorouraddin et al.   TALANTA

Evaluation of the matrix effect on gas chromatography – mass spectrometry with carrier gas containing ethylene glycol as an analyte protectant

(2016) Tomoharu Fujiyoshi et al.   JOURNAL OF CHROMATOGRAPHY A

Systematic evaluation of matrix effects in hydrophilic interaction chromatography versus reversed phase liquid chromatography coupled to mass spectrometry

(2016) Aurélie Periat et al.   JOURNAL OF CHROMATOGRAPHY A

Sample preparation with solid phase microextraction and exhaustive extraction approaches: Comparison for challenging cases

(2015) Ezel Boyacı et al.   ANALYTICA CHIMICA ACTA

Headspace versus Direct Immersion Solid Phase Microextraction in Complex Matrixes: Investigation of Analyte Behavior in Multicomponent Mixtures

(2015) Emanuela Gionfriddo et al.   ANALYTICAL CHEMISTRY

Biological Matrix Effects in Quantitative Tandem Mass Spectrometry-Based Analytical Methods: Advancing Biomonitoring

(2015) Parinya Panuwet et al.   CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY

How to Deal with the “Matrix Effect” as an Unavoidable Phenomenon

(2015) Miroslav Ryska   EUROPEAN JOURNAL OF MASS SPECTROMETRY

Development of an Automated Column Solid-Phase Extraction Cleanup of QuEChERS Extracts, Using a Zirconia-Based Sorbent, for Pesticide Residue Analyses by LC-MS/MS

(2015) Bruce D. Morris et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

A review of recent developments and trends in the QuEChERS sample preparation approach

(2015) Tomasz Rejczak et al.   Open Chemistry

Gradient elution mode for the troubleshooting of matrix effect on the determination of G004 in different tissues by LC-MS/MS

(2014) Linlin Hu et al.   BIOMEDICAL CHROMATOGRAPHY

Matrix effects break the LC behavior rule for analytes in LC-MS/MS analysis of biological samples

(2014) Nianbai Fang et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Effect of injection matrix concentration on peak shape and separation efficiency in ion chromatography

(2014) Ya Zhang et al.   JOURNAL OF CHROMATOGRAPHY A

Optimization and validation of a quantitative liquid chromatography–tandem mass spectrometric method covering 295 bacterial and fungal metabolites including all regulated mycotoxins in four model food matrices

(2014) Alexandra Malachová et al.   JOURNAL OF CHROMATOGRAPHY A

Determination of pyrethroid pesticides residues in vegetable oils using liquid–liquid extraction and dispersive liquid–liquid microextraction followed by gas chromatography–flame ionization detection

(2014) Mir Ali Farajzadeh et al.   JOURNAL OF FOOD COMPOSITION AND ANALYSIS

Matrix enhancement effect: A blessing or a curse for gas chromatography?—A review

(2013) Md. Musfiqur Rahman et al.   ANALYTICA CHIMICA ACTA

An analytical investigation of 24 oxygenated-PAHs (OPAHs) using liquid and gas chromatography–mass spectrometry

(2013) Steven G. O’Connell et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Dispersive liquid–liquid microextraction in food analysis. A critical review

(2013) Pilar Viñas et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Analysis of Multiple Anticoagulant Rodenticides in Animal Blood and Liver Tissue Using Principles of QuEChERS Method

(2013) D. Vudathala et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

Liquid phase microextraction for the analysis of trace elements and their speciation

(2013) Bin Hu et al.   SPECTROCHIMICA ACTA PART B-ATOMIC SPECTROSCOPY

Direct rapid analysis of multiple PPCPs in municipal wastewater using ultrahigh performance liquid chromatography–tandem mass spectrometry without SPE pre-concentration

(2012) Ke Yu et al.   ANALYTICA CHIMICA ACTA

Multiresidue Pesticide Analysis of Dried Botanical Dietary Supplements Using an Automated Dispersive SPE Cleanup for QuEChERS and High-Performance Liquid Chromatography–Tandem Mass Spectrometry

(2012) Yang Chen et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Low cost adsorbents for the removal of organic pollutants from wastewater

(2012) Imran Ali et al.   JOURNAL OF ENVIRONMENTAL MANAGEMENT

Multiple headspace solid-phase microextraction using a new fiber for avoiding matrix interferences in the quantitative determination of ethyl carbamate in pickles

(2012) Fen-Fen Lei et al.   JOURNAL OF SEPARATION SCIENCE

A Comparative Study on Three Analytical Methods for the Determination of the Neurotoxin BMAA in Cyanobacteria

(2012) Elisabeth J. Faassen et al.   PLoS One

Study of matrix-induced effects in multi-residue determination of pesticides by online gel permeation chromatography-gas chromatography/mass spectrometry

(2012) Sha Yu et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Mitigation of signal suppression caused by the use of trifluoroacetic acid in liquid chromatography mobile phases during liquid chromatography/mass spectrometry analysis via post-column addition of ammonium hydroxide

(2012) Chang-Ching Chan et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Electrospray Ionization Mass Spectrometry: A Technique to Access the Information beyond the Molecular Weight of the Analyte

(2012) Shibdas Banerjee et al.   International Journal of Analytical Chemistry

Overcoming matrix effects using the dilution approach in multiresidue methods for fruits and vegetables

(2011) Carmen Ferrer et al.   JOURNAL OF CHROMATOGRAPHY A

Assessment of sample cleanup and matrix effects in the pesticide residue analysis of foods using postcolumn infusion in liquid chromatography–tandem mass spectrometry

(2011) Stefan Kittlaus et al.   JOURNAL OF CHROMATOGRAPHY A

Multi-walled carbon nanotubes as alternative reversed-dispersive solid phase extraction materials in pesticide multi-residue analysis with QuEChERS method

(2011) Pengyue Zhao et al.   JOURNAL OF CHROMATOGRAPHY A

Multiresidue Pesticide Analysis in Fresh Produce by Capillary Gas Chromatography−Mass Spectrometry/Selective Ion Monitoring (GC-MS/SIM) and −Tandem Mass Spectrometry (GC-MS/MS)†

(2010) Jon W. Wong et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Solid phase extraction for removal of matrix effects in lipophilic marine toxin analysis by liquid chromatography-tandem mass spectrometry

(2009) Arjen Gerssen et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Dispersive liquid–liquid microextraction combined with high-performance liquid chromatography-UV detection as a very simple, rapid and sensitive method for the determination of bisphenol A in water samples

(2009) Mohammad Rezaee et al.   JOURNAL OF CHROMATOGRAPHY A

Signal suppression/enhancement in high-performance liquid chromatography tandem mass spectrometry

(2009) Fabio Gosetti et al.   JOURNAL OF CHROMATOGRAPHY A

Evolution of dispersive liquid–liquid microextraction method

(2009) Mohammad Rezaee et al.   JOURNAL OF CHROMATOGRAPHY A

Effect of eluent on the ionization process in liquid chromatography–mass spectrometry

(2008) Risto Kostiainen et al.   JOURNAL OF CHROMATOGRAPHY A

The effect of signal suppression and mobile phase composition on the simultaneous analysis of multiple classes of acidic/neutral pharmaceuticals and personal care products in surface water by solid-phase extraction and ultra performance liquid chromatography–negative electrospray tandem mass spectrometry

(2007) Barbara Kasprzyk-Hordern et al.   TALANTA