Study of the stereospecificity in the biotransformation of the four isomers of loxoprofen sodium in rats by chiral HPLC

Simultaneous stereoisomeric separation of loxoprofen sodium and its alcohol metabolites. Application to a stereoselective pharmacokinetic study

(2023) Shirong Cao et al.   Arabian Journal of Chemistry

Preliminary evidence of safety and effectiveness of Loxoprofen Sodium Cataplasm combined with physiotherapy for myofascial pain syndrome treatment: A randomized controlled pilot clinical trial

(2022) Xuewen Zhou et al.   Frontiers in Neurology

Loxoprofen enhances intestinal barrier function via generation of its active metabolite by carbonyl reductase 1 in differentiated Caco-2 cells

(2021) Satoshi Endo et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Enantioselective separation of nonsteroidal anti‐inflammatory drugs with amylose tris(3‐chloro‐5‐methylphenylcarbamate) stationary phase in HPLC with a focus on enantiomeric quality control in six pharmaceutical formulations containing racemic mixtures or single stereoisomers

(2021) Shirong Cao et al.   CHIRALITY

Enhancing effect of fumaric acid on transdermal penetration of loxoprofen sodium

(2020) Danping Zhang et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Efficacy and safety of loxoprofen sodium topical patch for the treatment of pain in patients with minor acute traumatic limb injuries in Brazil

(2019) Edison Noboru Fujiki et al.   PAIN

High performance liquid chromatography with photo diode array for separation and analysis of naproxen and esomeprazole in presence of their chiral impurities: Enantiomeric purity determination in tablets

(2017) Marwa A.A. Ragab et al.   JOURNAL OF CHROMATOGRAPHY A

Loxoprofen: A Review in Pain and Inflammation

(2016) Sarah L. Greig et al.   CLINICAL DRUG INVESTIGATION

Stereoselective Pharmacokinetics and Chiral Inversion of Ibuprofen in Adjuvant-induced Arthritic Rats

(2016) Hiroyuki Ikuta et al.   DRUG METABOLISM AND DISPOSITION

Topical Nonsteroidal Anti-Inflammatory Drugs

(2015) Robert L Barkin   AMERICAN JOURNAL OF THERAPEUTICS

Bioactivation of loxoprofen to a pharmacologically active metabolite and its disposition kinetics in human skin

(2015) Ryoko Sawamura et al.   BIOPHARMACEUTICS & DRUG DISPOSITION

Stereoselective Pharmacokinetics of Ketoprofen After Oral Administration of Modified-Release Formulations in Caucasian Healthy Subjects

(2015) Marianela Lorier et al.   EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS

Scope of partial least-squares regression applied to the enantiomeric composition determination of ketoprofen from strongly overlapped chromatographic profiles

(2015) Juan M. Padró et al.   JOURNAL OF SEPARATION SCIENCE

Efficacy and safety of loxoprofen hydrogel patch versus loxoprofen tablet in patients with knee osteoarthritis: a randomized controlled non-inferiority trial

(2014) Rong Mu et al.   CLINICAL RHEUMATOLOGY

Analysis of ibuprofen enantiomers in rat plasma by liquid chromatography with tandem mass spectrometry

(2014) Juciane Lauren Cavalcanti Cardoso et al.   JOURNAL OF SEPARATION SCIENCE

Enantioselective analysis of ibuprofen, ketoprofen and naproxen in wastewater and environmental water samples

(2011) Nor H. Hashim et al.   JOURNAL OF CHROMATOGRAPHY A