Mcl-1 involvement in mitochondrial dynamics is associated with apoptotic cell death

Mitochondrial Shape Governs BAX-Induced Membrane Permeabilization and Apoptosis

(2015) Thibaud T. Renault et al.   MOLECULAR CELL

p53 at the endoplasmic reticulum regulates apoptosis in a Ca2+-dependent manner

(2015) Carlotta Giorgi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The endoplasmic reticulum mitochondrial calcium cross talk is downregulated in malignant pleural mesothelioma cells and plays a critical role in apoptosis inhibition

(2015) Simone Patergnani et al.   Oncotarget

Mitochondrial Ca2+ Remodeling is a Prime Factor in Oncogenic Behavior

(2015) Alessandro Rimessi et al.   Frontiers in Oncology

Sabutoclax (BI97C1) and BI112D1, Putative Inhibitors of MCL-1, Induce Mitochondrial Fragmentation Either Upstream of or Independent of Apoptosis

(2015) Shankar Varadarajan et al.   NEOPLASIA

A dual role for the anti-apoptotic Bcl-2 protein in cancer: Mitochondria versus endoplasmic reticulum

(2014) Haidar Akl et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

(2014) L Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Persistent Mitochondrial Hyperfusion Promotes G2/M Accumulation and Caspase-Dependent Cell Death

(2014) Laura M. Westrate et al.   PLoS One

The endoplasmic reticulum–mitochondria connection: One touch, multiple functions

(2013) Saverio Marchi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Role of the c subunit of the FOATP synthase in mitochondrial permeability transition

(2013) Massimo Bonora et al.   CELL CYCLE

Identification of PTEN at the ER and MAMs and its regulation of Ca2+ signaling and apoptosis in a protein phosphatase-dependent manner

(2013) A Bononi et al.   CELL DEATH AND DIFFERENTIATION

Keeping mitochondria in shape: a matter of life and death

(2013) Luca Scorrano   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Clinical Trials Using Antisense Oligonucleotides in Duchenne Muscular Dystrophy

(2013) Taeyoung Koo et al.   HUMAN GENE THERAPY

The mitochondrial calcium uniporter complex: molecular components, structure and physiopathological implications

(2013) Saverio Marchi et al.   JOURNAL OF PHYSIOLOGY-LONDON

Ultrasensitive fluorescent proteins for imaging neuronal activity

(2013) Tsai-Wen Chen et al.   NATURE

Subcellular calcium measurements in mammalian cells using jellyfish photoprotein aequorin-based probes

(2013) Massimo Bonora et al.   Nature Protocols

Splice Modulating Therapies for Human Disease

(2012) Pietro Spitali et al.   CELL

Mitochondrial Ca2+ and apoptosis

(2012) Carlotta Giorgi et al.   CELL CALCIUM

Downregulation of the Mitochondrial Calcium Uniporter by Cancer-Related miR-25

(2012) Saverio Marchi et al.   CURRENT BIOLOGY

Anti-apoptotic MCL-1 localizes to the mitochondrial matrix and couples mitochondrial fusion to respiration

(2012) Rhonda M. Perciavalle et al.   NATURE CELL BIOLOGY

Delving deeper: MCL-1's contributions to normal and cancer biology

(2012) Rhonda M. Perciavalle et al.   TRENDS IN CELL BIOLOGY

Selective modulation of subtype III IP3R by Akt regulates ER Ca2+ release and apoptosis

(2012) S Marchi et al.   Cell Death & Disease

Modulation of biological processes in the nucleus by delivery of DNA oligonucleotides conjugated with gold nanoparticles

(2011) Dong-Wook Kim et al.   BIOMATERIALS

The role of PML in the control of apoptotic cell fate: a new key player at ER–mitochondria sites

(2011) P Pinton et al.   CELL DEATH AND DIFFERENTIATION

Mcl-1; the molecular regulation of protein function

(2010) Luke W. Thomas et al.   FEBS LETTERS

Apoptosis Protection by Mcl-1 and Bcl-2 Modulation of Inositol 1,4,5-Trisphosphate Receptor-dependent Ca2+Signaling

(2010) Emily F. Eckenrode et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Anti-tumor activity of splice-switching oligonucleotides

(2010) John A. Bauman et al.   NUCLEIC ACIDS RESEARCH

A survey of the anti-apoptotic Bcl-2 subfamily expression in cancer types provides a platform to predict the efficacy of Bcl-2 antagonists in cancer therapy

(2010) W J Placzek et al.   Cell Death & Disease

SnapShot: BCL-2 Proteins

(2009) J. Marie Hardwick et al.   CELL

MCL-1ES, a novel variant of MCL-1, associates with MCL-1L and induces mitochondrial cell death

(2009) Jae-Hong Kim et al.   FEBS LETTERS

Modification of Alternative Splicing of Mcl-1 Pre-mRNA Using Antisense Morpholino Oligonucleotides Induces Apoptosis in Basal Cell Carcinoma Cells

(2009) Jeng-Jer Shieh et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Isolation of mitochondria-associated membranes and mitochondria from animal tissues and cells

(2009) Mariusz R Wieckowski et al.   Nature Protocols

A hyperfused mitochondrial state achieved at G1-S regulates cyclin E buildup and entry into S phase

(2009) K. Mitra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intravesically administered antisense oligonucleotides targeting heat-shock protein-27 inhibit the growth of non-muscle-invasive bladder cancer

(2008) Boris A. Hadaschik et al.   BJU INTERNATIONAL