Establishment of “Ring-Size-Divergent” Synthetic Strategy: Divergent Synthesis, Stereochemical Assignments, and Biological Activity Studies of Nerolidol-Type Sesquiterpenoids and Feroniellins

Divergent Synthesis of Nerolidol-type Sesquiterpenoids Produced by Soil Bacterium from an Identical Starting Material via Diepoxide Precursors: Stereochemical Revision and Absolute Configuration of a THF Natural Product

(2022) Tomonori Teranishi et al.   CHEMISTRY LETTERS

Establishing a “Ring‐Size‐Divergent” Synthetic Strategy: Synthesis, Structural Revision, and Absolute Configuration of Feroniellins

(2021) Keisuke Nishikawa et al.   CHEMISTRY-A EUROPEAN JOURNAL

Bergamottin protects against LPS-induced endotoxic shock by regulating the NF-κB signaling pathway

(2021) Saisai Liu et al.   IMMUNOLOGIC RESEARCH

Critical Switching of Cyclization Modes of Polyepoxides in Acidic Aqueous Media and Neutral Water: Synthesis and Revised Structure of a Nerolidol-Type Sesquiterpenoid

(2019) Keisuke Nishikawa et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

From discoveries in ageing research to therapeutics for healthy ageing

(2019) Judith Campisi et al.   NATURE

Evaluation of Aculeatin and Toddaculin Isolated from Toddalia asiatica as Anti-inflammatory Agents in LPS-Stimulated RAW264 Macrophages

(2018) Momochika Kumagai et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Divergent Strategy in Natural Product Total Synthesis

(2018) Lei Li et al.   CHEMICAL REVIEWS

Senolytics improve physical function and increase lifespan in old age

(2018) Ming Xu et al.   NATURE MEDICINE

Anti-inflammatory activity of prenyl and geranyloxy furanocoumarins from Citrus garrawayi (Rutaceae)

(2018) Ritesh Raju et al.   Phytochemistry Letters

Structure determination of two new nerolidol-type sesquiterpenoids from the soil actinomyceteStreptomyces scopuliridis

(2016) Liya Li et al.   MAGNETIC RESONANCE IN CHEMISTRY

Quercetin, Inflammation and Immunity

(2016) Yao Li et al.   Nutrients

Biomimetic Total Synthesis of (−)-Neroplofurol and (+)-Ekeberin D4 Triggered by Hydrolysis of Terminal Epoxides

(2014) Takeshi Kodama et al.   CHEMISTRY LETTERS

Feroniellin A-induced autophagy causes apoptosis in multidrug-resistant human A549 lung cancer cells

(2014) CHUTIMA KAEWPIBOON et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

A Dioxane Template for Highly Selective Epoxy Alcohol Cyclizations

(2013) James J. Mousseau et al.   CHEMISTRY-A EUROPEAN JOURNAL

Selective Oxidation Reactions of Natural Compounds with Hydrogen Peroxide Mediated by Methyltrioxorhenium

(2013) Maria Amato et al.   MOLECULES

Biomimetic Epoxide-Opening Cascades of Oxasqualenoids Triggered by Hydrolysis of the Terminal Epoxide

(2013) Yoshiki Morimoto et al.   ORGANIC LETTERS

Enzymatic catalysis of anti-Baldwin ring closure in polyether biosynthesis

(2012) Kinya Hotta et al.   NATURE

Chemical constituents from the roots ofFeroniella lucida

(2011) Tawanun Sripisut et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Evidence That Epoxide-Opening Cascades Promoted by Water Are Stepwise and Become Faster and More Selective After the First Cyclization

(2011) Christopher J. Morten et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enzymatic Epoxide-Opening Cascades Catalyzed by a Pair of Epoxide Hydrolases in the Ionophore Polyether Biosynthesis

(2011) Atsushi Minami et al.   ORGANIC LETTERS

Synthesis of Marine Polycyclic Polyethers via Endo-Selective Epoxide-Opening Cascades

(2010) Ivan Vilotijevic et al.   Marine Drugs

Epoxide-Opening Cascades in the Synthesis of Polycyclic Polyether Natural Products

(2009) Ivan Vilotijevic et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The development of endo-selective epoxide-opening cascades in water

(2009) Christopher J. Morten et al.   CHEMICAL SOCIETY REVIEWS

On the Synergism Between H2O and a Tetrahydropyran Template in the Regioselective Cyclization of an Epoxy Alcohol

(2009) Jeffery A. Byers et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalytic Oxidation. Asymmetric Epoxidation of Olefins Catalyzed by Chiral Ketones and Iminium Salts

(2008) O. Andrea Wong et al.   CHEMICAL REVIEWS

The structure–activity relationship between oxycoumarin derivatives showing inhibitory effects on iNOS in mouse macrophage RAW264.7 cells

(2008) Tomonori Nakamura et al.   Journal of Natural Medicines

Epoxide Hydrolase Lsd19 for Polyether Formation in the Biosynthesis of Lasalocid A: Direct Experimental Evidence on Polyene-Polyepoxide Hypothesis in Polyether Biosynthesis

(2008) Yoshihiro Shichijo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The biosynthesis of polyketide-derived polycyclic ethers

(2008) Andrew R. Gallimore   NATURAL PRODUCT REPORTS