Thymoquinone inhibits growth of human medulloblastoma cells by inducing oxidative stress and caspase-dependent apoptosis while suppressing NF-κB signaling and IL-8 expression

Hexadecane degradation by bacterial strains isolated from contaminated soils

(2016) Abdel Megeed Ahmed et al.   AFRICAN JOURNAL OF BIOTECHNOLOGY

Evaluation of the protective effect of Nigella sativa extract and its primary active component thymoquinone against DMBA-induced breast cancer in female rats

(2015) Sabah A. A. Linjawi et al.   Archives of Medical Science

Anticancer Effects of Thymoquinone, Caffeic Acid Phenethyl Ester and Resveratrol on A549 Non-small Cell Lung Cancer Cells Exposed to Benzo(a)pyrene

(2014) Sevinc Sarinc Ulasli et al.   Asian Pacific Journal of Cancer Prevention

Thymoquinone suppression of the human hepatocellular carcinoma cell growth involves inhibition of IL-8 expression, elevated levels of TRAIL receptors, oxidative stress and apoptosis

(2014) Abdelkader E. Ashour et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Anti-inflammatuar and anti-oxidative effects of Nigella sativa L.: 18FDG-PET imaging of inflammation

(2014) Emre Entok et al.   MOLECULAR BIOLOGY REPORTS

Thymoquinone, A Bioactive Component of Black Caraway Seeds, Causes G1 Phase Cell Cycle Arrest and Apoptosis in Triple-Negative Breast Cancer Cells with Mutant p53

(2014) Kimberly M. Sutton et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Phosphorylated IκBα Predicts Poor Prognosis in Activated B-Cell Lymphoma and Its Inhibition with Thymoquinone Induces Apoptosis via ROS Release

(2013) Azhar R. Hussain et al.   PLoS One

Targeted Apoptotic Effects of Thymoquinone and Tamoxifen on XIAP Mediated Akt Regulation in Breast Cancer

(2013) Shashi Rajput et al.   PLoS One

Targeting the Inhibitor of Apoptosis Proteins as a Novel Therapeutic Strategy in Medulloblastoma

(2012) J. Keating et al.   MOLECULAR CANCER THERAPEUTICS

Anticancer activity of thymoquinone in breast cancer cells: Possible involvement of PPAR-γ pathway

(2011) Chern Chiuh Woo et al.   BIOCHEMICAL PHARMACOLOGY

Inhibition of nuclear factor kappa-B signaling reduces growth in medulloblastoma in vivo

(2011) Susan E Spiller et al.   BMC CANCER

Mitochondria in Apoptosis: Bcl-2 Family Members and Mitochondrial Dynamics

(2011) Jean-Claude Martinou et al.   DEVELOPMENTAL CELL

Thymoquinone suppresses growth and induces apoptosis via generation of reactive oxygen species in primary effusion lymphoma

(2011) Azhar R. Hussain et al.   FREE RADICAL BIOLOGY AND MEDICINE

Bortezomib stabilizes NOXA and triggers ROS-associated apoptosis in medulloblastoma

(2011) Sachiko Ohshima-Hosoyama et al.   JOURNAL OF NEURO-ONCOLOGY

Knockdown of CypA inhibits interleukin-8 (IL-8) and IL-8-mediated proliferation and tumor growth of glioblastoma cells through down-regulated NF-κB

(2010) Shan Sun et al.   JOURNAL OF NEURO-ONCOLOGY

Review on Molecular and Therapeutic Potential of Thymoquinone in Cancer

(2010) Sanjeev Banerjee et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Thymoquinone Induces Telomere Shortening, DNA Damage and Apoptosis in Human Glioblastoma Cells

(2010) Resham Lal Gurung et al.   PLoS One

ABINs: A20 binding inhibitors of NF-κB and apoptosis signaling

(2009) Lynn Verstrepen et al.   BIOCHEMICAL PHARMACOLOGY

Antimutagenic effects of ethanolic extracts from selected Palestinian medicinal plants

(2009) M. Khader et al.   JOURNAL OF ETHNOPHARMACOLOGY

Reactivation of death receptor 4 (DR4) expression sensitizes medulloblastoma cell lines to TRAIL

(2009) Dolly G. Aguilera et al.   JOURNAL OF NEURO-ONCOLOGY

Depletion of intrinsic expression of Interleukin-8 in prostate cancer cells causes cell cycle arrest, spontaneous apoptosis and increases the efficacy of chemotherapeutic drugs

(2009) Rajendra K Singh et al.   Molecular Cancer

In vitro and in vivo induction of apoptosis by capsaicin in pancreatic cancer cells is mediated through ROS generation and mitochondrial death pathway

(2008) Ruifen Zhang et al.   APOPTOSIS

Pediatric medulloblastoma: Toxicity of current treatment and potential role of protontherapy

(2008) Piero Fossati et al.   CANCER TREATMENT REVIEWS

Targeting Nuclear Factor- B Activation Pathway by Thymoquinone: Role in Suppression of Antiapoptotic Gene Products and Enhancement of Apoptosis

(2008) G. Sethi et al.   MOLECULAR CANCER RESEARCH