Journal
MOLECULAR AND BIOCHEMICAL PARASITOLOGY
Volume 210, Issue 1-2, Pages 10-12Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.molbiopara.2016.07.006
Keywords
Calorimetric LAMP; Onchocerciasis; O-150 repeat; Skin snips; Diagnosis
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Accurate, simple and affordable diagnostics are needed to detect Onchocerca volvulus infection in humans. A newly developed colorimetric loop-mediated isothermal amplification (LAMP) assay was compared to PCR and skin snip analysis for diagnosis of onchocerciasis. The robustness and simplicity of the assay indicates that it may be a useful field tool for surveillance in endemic countries. (C) 2016 The Author(s). Published by Elsevier B.V.
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