Evaluation of multiple immunoassay formats for detection of anti-drug antibodies to zinpentraxin alfa

Safety and efficacy of zinpentraxin alfa as monotherapy or in combination with ruxolitinib in myelofibrosis: stage I of a phase II trial

(2023) Srdan Verstovsek et al.   HAEMATOLOGICA

Fit-for-purpose validation of a drug-tolerant immunogenicity assay for a human mAb drug in animal safety studies

(2022) Akanksha Goyal et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Next Generation Therapeutics for the Treatment of Myelofibrosis

(2021) Douglas Tremblay et al.   Cells

Sensitive assay design for detection of anti-drug antibodies to biotherapeutics that lack an immunoglobulin Fc domain

(2021) Derrick Johnson et al.   Scientific Reports

Long-term treatment with recombinant human pentraxin 2 protein in patients with idiopathic pulmonary fibrosis: an open-label extension study

(2019) Ganesh Raghu et al.   Lancet Respiratory Medicine

Monoclonal antibodies as immunomodulatory therapy against cancer and autoimmune diseases

(2018) Umbreen Hafeez et al.   CURRENT OPINION IN PHARMACOLOGY

Effect of Recombinant Human Pentraxin 2 vs Placebo on Change in Forced Vital Capacity in Patients With Idiopathic Pulmonary Fibrosis

(2018) Ganesh Raghu et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

From the bench to clinical practice: understanding the challenges and uncertainties in immunogenicity testing for biopharmaceuticals

(2016) G. R. Gunn et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Protein A/G-based immunochromatographic test for serodiagnosis of pythiosis in human and animal subjects from Asia and Americas

(2016) Akarin Intaramat et al.   MEDICAL MYCOLOGY

Application of a Plug-and-Play Immunogenicity Assay in Cynomolgus Monkey Serum for ADCs at Early Stages of Drug Development

(2016) Montserrat Carrasco-Triguero et al.   Journal of Immunology Research

Evaluation of Multiple Immunoassay Technology Platforms to Select the Anti-Drug Antibody Assay Exhibiting the Most Appropriate Drug and Target Tolerance

(2016) Justine Collet-Brose et al.   Journal of Immunology Research

Novel association between serum pentraxin-2 levels and advanced fibrosis in well-characterised patients with non-alcoholic fatty liver disease

(2015) E. C. Verna et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

A breakthrough novel method to resolve the drug and target interference problem in immunogenicity assays

(2015) Jad Zoghbi et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Preventing intense false positive and negative reactions attributed to the principle of ELISA to re-investigate antibody studies in autoimmune diseases

(2014) Kuniaki Terato et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Development of a biosensor-based immunogenicity assay capable of blocking soluble drug target interference

(2013) Dohan K. Weeraratne et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Recombinant human serum amyloid P in healthy volunteers and patients with pulmonary fibrosis

(2013) M.R. Dillingh et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

PRM-151 (recombinant human serum amyloid P/pentraxin 2) for the treatment of fibrosis

(2010) J.S. Duffield et al.   DRUG NEWS & PERSPECTIVES

Detection of low-affinity anti-drug antibodies and improved drug tolerance in immunogenicity testing by Octet® biolayer interferometry

(2010) Jian Li et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Comparison of assay formats for drug-tolerant immunogenicity testing

(2010) Anthony M Butterfield et al.   Bioanalysis

Evaluation of an immunoassay for human-specific quantitation of therapeutic antibodies in serum samples from non-human primates

(2009) Kay Stubenrauch et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Serum Amyloid P Inhibits Fibrosis Through Fc R-Dependent Monocyte-Macrophage Regulation in Vivo

(2009) A. P. Castano et al.   Science Translational Medicine

Recommendations for the validation of immunoassays used for detection of host antibodies against biotechnology products

(2008) Gopi Shankar et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Amyloid accomplices and enforcers

(2004) Andrei T. Alexandrescu   PROTEIN SCIENCE