Identifiability of equilibrium constants for receptors with two to five binding sites

Kinetic fingerprinting of metabotropic glutamate receptors

(2023) Taulant Kukaj et al.   Communications Biology

A strategy for determining the equilibrium constants for heteromeric ion channels in a complex model

(2022) Klaus Benndorf et al.   JOURNAL OF GENERAL PHYSIOLOGY

Subunit promotion energies for channel opening in heterotetrameric olfactory CNG channels

(2022) Jana Schirmeyer et al.   PLoS Computational Biology

Dissecting activation steps in P2X7 receptors

(2021) Milica Gusic et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Architecture and assembly mechanism of native glycine receptors

(2021) Hongtao Zhu et al.   NATURE

Thermodynamic profile of mutual subunit control in a heteromeric receptor

(2021) Jana Schirmeyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Concatemers to re-investigate the role of α5 in α4β2 nicotinic receptors

(2020) Marie S. Prevost et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Determining the correct stoichiometry of Kv2.1/Kv6.4 heterotetramers, functional in multiple stoichiometrical configurations

(2020) Lena Möller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

What is the correct stoichiometry of Kv2.1:Kv6.4 heteromers?

(2020) Aditya Pisupati et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stepwise activation of a class C GPCR begins with millisecond dimer rearrangement

(2019) Eugene O. Grushevskyi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of the Cardiac Sodium Channel

(2019) Daohua Jiang et al.   CELL

All four subunits of HCN2 channels contribute to the activation gating in an additive but intricate manner

(2018) Mallikarjuna Rao Sunkara et al.   JOURNAL OF GENERAL PHYSIOLOGY

Applying the Monod-Wyman-Changeux Allosteric Activation Model to Pseudo–Steady-State Responses from GABAA Receptors

(2018) Joe Henry Steinbach et al.   MOLECULAR PHARMACOLOGY

Structure of a eukaryotic cyclic-nucleotide-gated channel

(2017) Minghui Li et al.   NATURE

α4β2 Nicotinic Acetylcholine Receptors

(2016) Simone Mazzaferro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural identifiability of equilibrium ligand-binding parameters

(2016) Thomas R. Middendorf et al.   JOURNAL OF GENERAL PHYSIOLOGY

The structure of binding curves and practical identifiability of equilibrium ligand-binding parameters

(2016) Thomas R. Middendorf et al.   JOURNAL OF GENERAL PHYSIOLOGY

Quantifying the cooperative subunit action in a multimeric membrane receptor

(2016) Nisa Wongsamitkul et al.   Scientific Reports

Structure of the voltage-gated calcium channel Cav1.1 complex

(2015) J. Wu et al.   SCIENCE

Determination of parameter identifiability in nonlinear biophysical models: A Bayesian approach

(2014) Keegan E. Hines et al.   JOURNAL OF GENERAL PHYSIOLOGY

Gating of Pentameric Ligand-Gated Ion Channels: Structural Insights and Ambiguities

(2013) Corrie J.B. daCosta et al.   STRUCTURE

Molecular mechanism of ATP binding and ion channel activation in P2X receptors

(2012) Motoyuki Hattori et al.   NATURE

Use of Concatemers of Ligand-Gated Ion Channel Subunits to Study Mechanisms of Steroid Potentiation

(2011) Joe Henry Steinbach et al.   ANESTHESIOLOGY

Arrangement of Kv1 α subunits dictates sensitivity to tetraethylammonium

(2010) Ahmed Al-Sabi et al.   JOURNAL OF GENERAL PHYSIOLOGY

Interdependence of Receptor Activation and Ligand Binding in HCN2 Pacemaker Channels

(2010) Jana Kusch et al.   NEURON

X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor

(2009) Alexander I. Sobolevsky et al.   NATURE

Crystal structure of the ATP-gated P2X4 ion channel in the closed state

(2009) Toshimitsu Kawate et al.   NATURE