Design, synthesis, conformational analysis, and biological activity of Cα 1 -to-Cα 6 1,4- and 4,1-disubstituted 1 H -[1,2,3]triazol-1-yl-bridged oxytocin analogues

The oxytocin signaling complex reveals a molecular switch for cation dependence

(2022) Justin G. Meyerowitz et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural basis for the activation and ligand recognition of the human oxytocin receptor

(2022) Yann Waltenspühl et al.   Nature Communications

Oxytocin: at birth and beyond. A systematic review of the long‐term effects of peripartum oxytocin

(2021) D. T. Monks et al.   ANAESTHESIA

Oxytocin receptor is a promising therapeutic target of malignant mesothelioma

(2021) Yuta Kodama et al.   CANCER SCIENCE

1,4-Disubstituted 1,2,3-Triazoles as Amide Bond Surrogates for the Stabilisation of Linear Peptides with Biological Activity

(2020) Lisa-Maria Rečnik et al.   MOLECULES

The oxytocin receptor signalling system and breast cancer: a critical review

(2020) Huiping Liu et al.   ONCOGENE

Is Oxytocin “Nature’s Medicine”?

(2020) C. Sue Carter et al.   PHARMACOLOGICAL REVIEWS

Development and characterisation of novel, enzymatically stable oxytocin analogues with beneficial antidiabetic effects in high fat fed mice

(2020) Shruti Mohan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Recent applications of click chemistry in drug discovery

(2019) Xiangyi Jiang et al.   Expert Opinion on Drug Discovery

I8-arachnotocin–an arthropod-derived G protein-biased ligand of the human vasopressin V2 receptor

(2019) Leopold Duerrauer et al.   Scientific Reports

Copper-Catalyzed Azide-Alkyne Cycloaddition (CuAAC)-Mediated Macrocyclization of Peptides: Impact on Conformation and Biological Activity

(2018) Chiara Testa et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Advances in the role of oxytocin receptors in human parturition

(2017) Sung Hye Kim et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Development of a human vasopressin V1a-receptor antagonist from an evolutionary-related insect neuropeptide

(2017) Maria Giulia Di Giglio et al.   Scientific Reports

ff14SB: Improving the Accuracy of Protein Side Chain and Backbone Parameters from ff99SB

(2015) James A. Maier et al.   Journal of Chemical Theory and Computation

CuAAC: An Efficient Click Chemistry Reaction on Solid Phase

(2015) Vida Castro et al.   ACS Combinatorial Science

Oxytocin and bone

(2014) Graziana Colaianni et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

NMRFAM-SPARKY: enhanced software for biomolecular NMR spectroscopy

(2014) Woonghee Lee et al.   BIOINFORMATICS

1,4-Disubstituted-[1,2,3]triazolyl-Containing Analogues of MT-II: Design, Synthesis, Conformational Analysis, and Biological Activity

(2014) Chiara Testa et al.   JOURNAL OF MEDICINAL CHEMISTRY

Selenoether oxytocin analogues have analgesic properties in a mouse model of chronic abdominal pain

(2014) Aline Dantas de Araujo et al.   Nature Communications

Oxytocin and Pain

(2013) Joshua A. Rash et al.   CLINICAL JOURNAL OF PAIN

Oxytocic plant cyclotides as templates for peptide G protein-coupled receptor ligand design

(2013) J. Koehbach et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Solvent independent conformational propensities of [1,2,3]triazolyl-bridged parathyroid hormone-related peptide-derived cyclo-nonapeptide analogues

(2012) Mario Scrima et al.   BIOPOLYMERS

Exploring bioactive peptides from natural sources for oxytocin and vasopressin drug discovery

(2012) Christian W Gruber et al.   Future Medicinal Chemistry

Maintaining Biological Activity by Using Triazoles as Disufide Bond Mimetics

(2011) Kai Holland-Nell et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Site-Specific Effects of Diselenide Bridges on the Oxidative Folding of a Cystine Knot Peptide, ω-Selenoconotoxin GVIA

(2010) Konkallu Hanumae Gowd et al.   BIOCHEMISTRY

Modulating Oxytocin Activity and Plasma Stability by Disulfide Bond Engineering

(2010) Markus Muttenthaler et al.   JOURNAL OF MEDICINAL CHEMISTRY

Solving the α-Conotoxin Folding Problem: Efficient Selenium-Directed On-Resin Generation of More Potent and Stable Nicotinic Acetylcholine Receptor Antagonists

(2010) Markus Muttenthaler et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Integrated Oxidative Folding of Cysteine/Selenocysteine Containing Peptides: Improving Chemical Synthesis of Conotoxins

(2009) Aleksandra Walewska et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Role of Thiols and Disulfides on Protein Stability

(2009) Maulik Trivedi et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Structure and Activity of (2,8)-Dicarba-(3,12)-cystino α-ImI, an α-Conotoxin Containing a Nonreducible Cystine Analogue†

(2009) Christopher A. MacRaild et al.   JOURNAL OF MEDICINAL CHEMISTRY

Pharmacokinetics of carbetocin, a long-acting oxytocin analogue, following intravenous administration in horses

(2008) A. R. SCHRAMME et al.   EQUINE VETERINARY JOURNAL

Nα-Fmoc-Protected ω-Azido- and ω-Alkynyl-L-amino Acids as Building Blocks for the Synthesis of “Clickable” Peptides

(2008) Alexandra Le Chevalier Isaad et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Synthesis and Conformational Analysis of a Cyclic Peptide Obtained viaitoi+4 Intramolecular Side-Chain to Side-Chain Azide−Alkyne 1,3-Dipolar Cycloaddition

(2008) Sonia Cantel et al.   JOURNAL OF ORGANIC CHEMISTRY

Selenopeptide chemistry

(2008) Markus Muttenthaler et al.   JOURNAL OF PEPTIDE SCIENCE