An integrin-targeted photoactivatable Pt(iv) complex as a selective anticancer pro-drug: synthesis and photoactivation studies

Integrin-targeted delivery into cancer cells of a Pt(iv) pro-drug through conjugation to RGD-containing peptides

(2015) Anna Massaguer et al.   DALTON TRANSACTIONS

A Bis(dipyridophenazine)(2-(2-pyridyl)pyrimidine-4-carboxylic acid)ruthenium(II) Complex with Anticancer Action upon Photodeprotection

(2014) Tanmaya Joshi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cellular Accumulation, Lipophilicity and Photocytotoxicity of Diazido Platinum(IV) Anticancer Complexes

(2014) Ana M. Pizarro et al.   ChemMedChem

Strategies To Inhibit Tumor Associated Integrin Receptors: Rationale for Dual and Multi-Antagonists

(2014) Helen M. Sheldrake et al.   JOURNAL OF MEDICINAL CHEMISTRY

Targeted Theranostic Platinum(IV) Prodrug with a Built-In Aggregation-Induced Emission Light-Up Apoptosis Sensor for Noninvasive Early Evaluation of Its Therapeutic Responses in Situ

(2014) Youyong Yuan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Photo-induced uncaging of a specific Re(i) organometallic complex in living cells

(2014) Anna Leonidova et al.   Chemical Science

Activation of a Photodissociative Ruthenium Complex by Triplet-Triplet Annihilation Upconversion in Liposomes

(2013) Sven H. C. Askes et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Diazido Mixed-Amine Platinum(IV) Anticancer Complexes Activatable by Visible-Light Form Novel DNA Adducts

(2013) Yao Zhao et al.   CHEMISTRY-A EUROPEAN JOURNAL

Spontaneous Formation in the Dark, and Visible Light-Induced Cleavage, of a Ru–S Bond in Water: A Thermodynamic and Kinetic Study

(2013) Azadeh Bahreman et al.   INORGANIC CHEMISTRY

Photoactivatable metal complexes: from theory to applications in biotechnology and medicine

(2013) N. A. Smith et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES

αVβ3 Integrin-Targeted PLGA-PEG Nanoparticles for Enhanced Anti-tumor Efficacy of a Pt(IV) Prodrug

(2012) Nora Graf et al.   ACS Nano

Interactions of DNA with a New Platinum(IV) Azide Dipyridine Complex Activated by UVA and Visible Light: Relationship to Toxicity in Tumor Cells

(2012) Jitka Pracharova et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Radiolabelled RGD peptides for imaging and therapy

(2012) F. C. Gaertner et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Combined Theoretical and Computational Study of Interstrand DNA Guanine–Guanine Cross-Linking by trans-[Pt(pyridine)2] Derived from the Photoactivated Prodrug trans,trans,trans-[Pt(N3)2(OH)2(pyridine)2]

(2012) Hui-Chung Tai et al.   INORGANIC CHEMISTRY

RGD-Based Strategies To Target Alpha(v) Beta(3) Integrin in Cancer Therapy and Diagnosis

(2012) Fabienne Danhier et al.   MOLECULAR PHARMACEUTICS

Matched rabbit monoclonal antibodies against  v-series integrins reveal a novel  v 3-LIBS epitope, and permit routine staining of archival paraffin samples of human tumors

(2012) S. L. Goodman et al.   Biology Open

Cilengitide: The First Anti-Angiogenic Small Molecule Drug Candidate. Design, Synthesis and Clinical Evaluation

(2011) Carlos Mas-Moruno et al.   Anti-Cancer Agents in Medicinal Chemistry

N-Acetylmethionine and Biotin as Photocleavable Protective Groups for Ruthenium Polypyridyl Complexes

(2011) Roosmarijn E. Goldbach et al.   CHEMISTRY-A EUROPEAN JOURNAL

Photocontrolled DNA Binding of a Receptor-Targeted Organometallic Ruthenium(II) Complex

(2011) Flavia Barragán et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Potent Trans-Diimine Platinum Anticancer Complex Photoactivated by Visible Light

(2010) Nicola J. Farrer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Potential photoactivated metallopharmaceuticals: from active molecules to supported drugs

(2010) Daniel Crespy et al.   CHEMICAL COMMUNICATIONS

Targeting αvβ3 Integrin: Design and Applications of Mono- and Multifunctional RGD-Based Peptides and Semipeptides

(2010) L. Auzzas et al.   CURRENT MEDICINAL CHEMISTRY

Photocontrolled nucleobase binding to an organometallic RuII arene complex

(2009) Soledad Betanzos-Lara et al.   CHEMICAL COMMUNICATIONS

From cisplatin to photoreactive Ru complexes: targeting DNA for biomedical applications

(2008) Cécile Moucheron   NEW JOURNAL OF CHEMISTRY

Conjugated Platinum(IV)−Peptide Complexes for Targeting Angiogenic Tumor Vasculature

(2007) Sumitra Mukhopadhyay et al.   BIOCONJUGATE CHEMISTRY