Twofold polyketide branching by a stereoselective enzymatic Michael addition

Decoding and reprogramming complex polyketide assembly lines: prospects for synthetic biology

(2015) Christian Hertweck   TRENDS IN BIOCHEMICAL SCIENCES

Enzymatic Polyketide Chain Branching To Give Substituted Lactone, Lactam, and Glutarimide Heterocycles

(2014) Daniel Heine et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Assembly Line Polyketide Synthases: Mechanistic Insights and Unsolved Problems

(2014) Chaitan Khosla et al.   BIOCHEMISTRY

Comparative Analysis of the Substrate Specificity of trans- versus cis-Acyltransferases of Assembly Line Polyketide Synthases

(2014) Briana J. Dunn et al.   BIOCHEMISTRY

Vinylogous chain branching catalysed by a dedicated polyketide synthase module

(2013) Tom Bretschneider et al.   NATURE

Symbiotic Cooperation in the Biosynthesis of a Phytotoxin

(2012) Kirstin Scherlach et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Evolution of an endofungal Lifestyle: Deductions from the Burkholderia rhizoxinica Genome

(2011) Gerald Lackner et al.   BMC GENOMICS

Antiproliferative Effects of Ester- and Amide-Functionalized Rhizoxin Derivatives

(2011) Björn Kusebauch et al.   ChemMedChem

A ketosynthase homolog uses malonyl units to form esters in cervimycin biosynthesis

(2011) Tom Bretschneider et al.   Nature Chemical Biology

Impact of Endofungal Bacteria on Infection Biology, Food Safety, and Drug Development

(2011) Gerald Lackner et al.   PLoS Pathogens

Complete Genome Sequence of Burkholderia rhizoxinica, an Endosymbiont of Rhizopus microsporus

(2010) G. Lackner et al.   JOURNAL OF BACTERIOLOGY

Biosynthesis of polyketides by trans-AT polyketide synthases

(2010) Jörn Piel   NATURAL PRODUCT REPORTS

Functionally Distinct Modules Operate Two Consecutive α,β→β,γ Double-Bond Shifts in the Rhizoxin Polyketide Assembly Line

(2009) Björn Kusebauch et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Polyketide-Chain Branching by an Enzymatic Michael Addition

(2009) Björn Kusebauch et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Biosynthetic Logic of Polyketide Diversity

(2009) Christian Hertweck   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Endofungal bacteria as producers of mycotoxins

(2009) Gerald Lackner et al.   TRENDS IN MICROBIOLOGY

In Vivo and In Vitro Trans-Acylation by BryP, the Putative Bryostatin Pathway Acyltransferase Derived from an Uncultured Marine Symbiont

(2008) Nicole B. Lopanik et al.   CHEMISTRY & BIOLOGY

Evolution of host resistance in a toxin-producing bacterial–fungal alliance

(2008) Imke Schmitt et al.   ISME Journal

Isoprenoid-like alkylations in polyketide biosynthesis

(2008) Christopher T. Calderone   NATURAL PRODUCT REPORTS

Biosynthesis of polyketide synthase extender units

(2008) Yolande A. Chan et al.   NATURAL PRODUCT REPORTS

Exploiting the mosaic structure of trans-acyltransferase polyketide synthases for natural product discovery and pathway dissection

(2008) TuAnh Nguyen et al.   NATURE BIOTECHNOLOGY