Journal
CHEMICAL COMMUNICATIONS
Volume 51, Issue 17, Pages 3574-3577Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc10246k
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Funding
- National Science Foundation [CAREER 0847222]
- National Institutes of Health (NIGMS) [1R15GM097708-01]
- Division Of Chemistry
- Direct For Mathematical & Physical Scien [0847222] Funding Source: National Science Foundation
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A new approach for the direct amination of 2-phenylpyridine derivatives using a diphthalimide-iodane and copper triflate has been developed. A series of different 2-phenylpyridine derivatives were aminated with yields up to 88%. Mechanistic investigations indicate that the reaction proceeds via a copper-mediated single electron transfer.
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