Possible role of HE4 level elevation in the pathogenesis of TH2-high asthma

Liquid biopsy-based decision support algorithms for diagnosis and subtyping of lung cancer

(2023) Esther Visser et al.   LUNG CANCER

Airway remodelling rather than cellular infiltration characterizes both type2 cytokine biomarker‐high and ‐low severe asthma

(2022) Latifa Khalfaoui et al.   ALLERGY

Chloride channel accessory 1 gene deficiency causes selective loss of mucus production in a new pig model

(2022) Shamus P. Keeler et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Longitudinal Impact of Sputum Inflammatory Phenotypes on Small Airway Dysfunction and Disease Outcomes in Asthma

(2022) Mustafa Abdo et al.   Journal of Allergy and Clinical Immunology-In Practice

Biologics and Airway Remodeling in Severe Asthma

(2022) Gilda Varricchi et al.   ALLERGY

Human epididymis protein 4 is associated with severity and poor prognosis of connective tissue disease-associated interstitial lung disease with usual interstitial pneumonia pattern

(2022) Kaifang Meng et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Involvement of CXCL17 and GPR35 in Gastric Cancer Initiation and Progression

(2022) Yizhi Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

GOLD COPD report: 2023 update

(2022) Priya Venkatesan   Lancet Respiratory Medicine

The cryptic role of CXCL17/CXCR8 axis in the pathogenesis of cancers: a review of the latest evidence

(2022) Seyyede Fatemeh Hashemi et al.   Journal of Cell Communication and Signaling

CLCA1 Regulates Airway Mucus Production and Ion Secretion Through TMEM16A

(2021) Raquel Centeio et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Asthma in the Precision Medicine Era: Biologics and Probiotics

(2021) Chiao-Juno Chiu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

HE4 Overexpression by Ovarian Cancer Promotes a Suppressive Tumor Immune Microenvironment and Enhanced Tumor and Macrophage PD-L1 Expression

(2021) Rachael B. Rowswell-Turner et al.   JOURNAL OF IMMUNOLOGY

Enhanced Expression of Human Epididymis Protein 4 (HE4) Reflecting Pro-Inflammatory Status Is Regulated by CFTR in Cystic Fibrosis Bronchial Epithelial Cells

(2021) Zsolt Bene et al.   Frontiers in Pharmacology

Epithelial microRNA-206 targets CD39/extracellular ATP to upregulate airway IL-25 and TSLP in type 2-high asthma

(2021) Kan Zhang et al.   JCI Insight

WFDC2 Promotes Spasmolytic Polypeptide-Expressing Metaplasia Through the Up-Regulation of IL33 in Response to Injury

(2021) Haengdueng Jeong et al.   GASTROENTEROLOGY

Serum Human Epididymis Protein 4 as a Novel Biomarker in Identifying Patients With Interstitial Lung Disease in Rheumatoid Arthritis

(2021) Liu Liang et al.   Frontiers in Medicine

Type 2 immunity in the skin and lungs

(2020) Cezmi A. Akdis et al.   ALLERGY

Oxidative stress-based therapeutics in COPD

(2020) Peter J. Barnes   Redox Biology

The Cytokines of Asthma

(2019) Bart N. Lambrecht et al.   IMMUNITY

Eosinophilic Asthma

(2019) Ryan K. Nelson et al.   Journal of Allergy and Clinical Immunology-In Practice

Decreased epithelial and sputum miR-221-3p associates with airway eosinophilic inflammation and CXCL17 expression in asthma

(2018) Kan Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

HE4 suppresses the expression of osteopontin in mononuclear cells and compromises their cytotoxicity against ovarian cancer cells

(2018) Nicole E. James et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Tight junction, mucin, and inflammasome-related molecules are differentially expressed in eosinophilic, mixed, and neutrophilic experimental asthma in mice

(2018) Hern-Tze Tina Tan et al.   ALLERGY

Epithelial SERPINB10, a novel marker of airway eosinophilia in asthma, contributes to allergic airway inflammation

(2018) Yuqing Mo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Ectopic expression of the chemokine CXCL17 in colon cancer cells

(2016) Lina Ohlsson et al.   BRITISH JOURNAL OF CANCER

Human Epididymis Protein 4: A Novel Serum Inflammatory Biomarker in Cystic Fibrosis

(2016) Béla Nagy et al.   CHEST

Inflammatory mechanisms in patients with chronic obstructive pulmonary disease

(2016) Peter J. Barnes   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Allergen-induced airway responses

(2015) Gail M. Gauvreau et al.   EUROPEAN RESPIRATORY JOURNAL

Epithelial Interleukin-25 Is a Key Mediator in Th2-High, Corticosteroid-Responsive Asthma

(2014) Dan Cheng et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Serum human epididymis protein 4 (HE4) as a tumor marker in men with lung cancer

(2014) Béla Nagy et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Dissecting childhood asthma with nasal transcriptomics distinguishes subphenotypes of disease

(2014) Alex Poole et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Measures of gene expression in sputum cells can identify TH2-high and TH2-low subtypes of asthma

(2013) Michael C. Peters et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A qPCR-based metric of Th2 airway inflammation in asthma

(2013) Nirav R Bhakta et al.   Clinical and Translational Allergy

CXCL17 Is a Mucosal Chemokine Elevated in Idiopathic Pulmonary Fibrosis That Exhibits Broad Antimicrobial Activity

(2012) A. M. Burkhardt et al.   JOURNAL OF IMMUNOLOGY

The airway epithelium in asthma

(2012) Bart N Lambrecht et al.   NATURE MEDICINE

Human Epididymis Protein-4 (HE-4): A Novel Cross-Class Protease Inhibitor

(2012) Nirmal Chhikara et al.   PLoS One

CXCL17 and ICAM2 Are Associated With a Potential Anti-Tumor Immune Response in Early Intraepithelial Stages of Human Pancreatic Carcinogenesis

(2010) Nobuyoshi Hiraoka et al.   GASTROENTEROLOGY

Airway Mucus Function and Dysfunction

(2010) John V. Fahy et al.   NEW ENGLAND JOURNAL OF MEDICINE

Serum HE4 concentration differentiates malignant ovarian tumours from ovarian endometriotic cysts

(2009) K Huhtinen et al.   BRITISH JOURNAL OF CANCER