Antitumor activity of the new tyrphostin briva against BRAFV600E-mutant colorectal carcinoma cells

Apoptosis induction in human lung and colon cancer cells via impeding VEGF signaling pathways

(2022) Maryam Farzaneh Behelgardi et al.   MOLECULAR BIOLOGY REPORTS

BRAF Inhibitor Resistance in Melanoma: Mechanisms and Alternative Therapeutic Strategies

(2022) Yong Chen et al.   CURRENT TREATMENT OPTIONS IN ONCOLOGY

A phase II study of daily encorafenib in combination with biweekly cetuximab in patients with BRAF V600E mutated metastatic colorectal cancer: the NEW BEACON study

(2022) Martina Eriksen et al.   BMC CANCER

The role of activated androgen receptor in cofilin phospho-regulation depends on the molecular subtype of TNBC cell line and actin assembly dynamics

(2022) Lubna Tahtamouni et al.   PLoS One

WNT5A-ROR2 axis mediates VEGF dependence of BRAF mutant melanoma

(2022) Nicholas Coupe et al.   CELLULAR ONCOLOGY

Defining and Targeting BRAF Mutations in Solid Tumors

(2021) Briana R. Halle et al.   CURRENT TREATMENT OPTIONS IN ONCOLOGY

New 3-Aryl-2-(2-thienyl)acrylonitriles with High Activity Against Hepatoma Cells

(2021) Eva Schaller et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Management of BRAF-mutant metastatic colorectal cancer: a review of treatment options and evidence-based guidelines

(2021) A. Grothey et al.   ANNALS OF ONCOLOGY

Intracellular Progesterone Receptor and cSrc Protein Working Together to Regulate the Activity of Proteins Involved in Migration and Invasion of Human Glioblastoma Cells

(2021) Claudia Bello-Alvarez et al.   Frontiers in Endocrinology

Triple-Regimen of Vemurafenib, Irinotecan, and Cetuximab for the Treatment of BRAFV600E-Mutant CRC: A Case Report and Review

(2021) Su Min Cho et al.   Frontiers in Pharmacology

BRAF mutant colorectal cancer: ErbB2 expression levels as predictive factor for the response to combined BRAF/ErbB inhibitors

(2020) Evelina Miele et al.   BMC CANCER

Adjuvant bevacizumab for melanoma patients at high risk of recurrence: survival analysis of the AVAST-M trial

(2018) P G Corrie et al.   ANNALS OF ONCOLOGY

Evolution of regorafenib from bench to bedside in colorectal cancer: Is it an attractive option or merely a “me too” drug?

(2018) Gaurav Goel   Cancer Management and Research

Colorectal Cancer in the Arab World - Screening Practices and Future Prospects

(2015) Mostafa A Arafa et al.   Asian Pacific Journal of Cancer Prevention

Synthesis and evaluation of a series of quinolinyl trans-cyanostilbene analogs as anticancer agents

(2014) Narsimha Reddy Penthala et al.   MedChemComm

Synthesis and evaluation of (Z)-2,3-diphenylacrylonitrile analogs as anti-cancer and anti-microbial agents

(2013) Mohammad Sayed Alam et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design and synthesis of novel DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitors: 3. Evaluation of 5-amino-linked thiazolo[5,4-d]pyrimidine and thiazolo[5,4-b]pyridine derivatives

(2012) Masaaki Hirose et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Cytotoxic 2-phenyacrylnitriles, the importance of the cyanide moiety and discovery of potent broad spectrum cytotoxic agents

(2012) Mark Tarleton et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Combined BRAF and MEK Inhibition in Melanoma with BRAF V600 Mutations

(2012) Keith T. Flaherty et al.   NEW ENGLAND JOURNAL OF MEDICINE

BRAF Inhibitors and Melanoma

(2011) Keith T. Flaherty   CANCER JOURNAL

3-Aryl-2-[1H-benzotriazol-1-yl]acrylonitriles: A novel class of potent tubulin inhibitors

(2011) Antonio Carta et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Novel Acrylonitrile Derivatives, YHO-13177 and YHO-13351, Reverse BCRP/ABCG2-Mediated Drug Resistance In Vitro and In Vivo

(2011) R. Yamazaki et al.   MOLECULAR CANCER THERAPEUTICS

Relocation of Aurora B and Survivin from Centromeres to the Central Spindle Impaired by a Kinesin-Specific MKLP-2 Inhibitor

(2010) Sergey Tcherniuk et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

(Arene)Ru(II) complexes of epidermal growth factor receptor inhibiting tyrphostins with enhanced selectivity and cytotoxicity in cancer cells

(2010) B. Biersack et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Cell adhesion: integrating cytoskeletal dynamics and cellular tension

(2010) J. Thomas Parsons et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

BRAF Gene Amplification Can Promote Acquired Resistance to MEK Inhibitors in Cancer Cells Harboring the BRAF V600E Mutation

(2010) R. B. Corcoran et al.   Science Signaling

Library synthesis and cytotoxicity of a family of 2-phenylacrylonitriles and discovery of an estrogen dependent breast cancer lead compound

(2010) Mark Tarleton et al.   MedChemComm