Synthetic heparan sulfate dodecasaccharides reveal single sulfation site interconverts CXCL8 and CXCL12 chemokine biology

Synthesis of the Heparin-Based Anticoagulant Drug Fondaparinux

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Homogeneous low-molecular-weight heparins with reversible anticoagulant activity

(2014) Yongmei Xu et al.   Nature Chemical Biology

Synthetic heparin and heparan sulfate oligosaccharides and their protein interactions

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Pathophysiology of heparan sulphate: many diseases, few drugs

(2013) U. Lindahl et al.   JOURNAL OF INTERNAL MEDICINE

CCL19/CCR7 upregulates heparanase via specificity protein-1 (Sp1) to promote invasion of cell in lung cancer

(2013) Qingfu Zhang et al.   TUMOR BIOLOGY

Efficient chemical synthesis of heparin-like octa-, deca- and dodecasaccharides and inhibition of FGF2- and VEGF165-mediated endothelial cell functions

(2013) Gavin J. Miller et al.   Chemical Science

Inactivation of heparan sulfate 2-O-sulfotransferase accentuates neutrophil infiltration during acute inflammation in mice

(2012) J. Axelsson et al.   BLOOD

The influence of glycosaminoglycans on IL-8-mediated functions of neutrophils

(2012) Denise Schlorke et al.   CARBOHYDRATE RESEARCH

The biology of chemokines and their receptors

(2012) Sergio A. Lira et al.   IMMUNOLOGIC RESEARCH

Heparin Oligosaccharides Inhibit Chemokine (CXC Motif) Ligand 12 (CXCL12) Cardioprotection by Binding Orthogonal to the Dimerization Interface, Promoting Oligomerization, and Competing with the Chemokine (CXC Motif) Receptor 4 (CXCR4) N Terminus

(2012) Joshua J. Ziarek et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endothelial Heparan Sulfate 6-O-Sulfation Levels Regulate Angiogenic Responses of Endothelial Cells to Fibroblast Growth Factor 2 and Vascular Endothelial Growth Factor

(2012) Cristina Ferreras et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synthesis and Scalable Conversion of l-Iduronamides to Heparin-Related Di- and Tetrasaccharides

(2012) Steen U. Hansen et al.   JOURNAL OF ORGANIC CHEMISTRY

Glycosaminoglycan analogs as a novel anti-inflammatory strategy

(2012) India C. Severin et al.   Frontiers in Immunology

Highly Sulfated Nonreducing End-derived Heparan Sulfate Domains Bind Fibroblast Growth Factor-2 with High Affinity and Are Enriched in Biologically Active Fractions

(2011) Hicham Naimy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Extracellular matrix and cell signalling: the dynamic cooperation of integrin, proteoglycan and growth factor receptor

(2011) Soo-Hyun Kim et al.   JOURNAL OF ENDOCRINOLOGY

Synthesis of 3-O-sulfonated heparan sulfate octasaccharides that inhibit the herpes simplex virus type 1 host–cell interaction

(2011) Yu-Peng Hu et al.   Nature Chemistry

Heparan Sulfate Domain Organization and Sulfation Modulate FGF-induced Cell Signaling

(2010) Nadja Jastrebova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Disaccharide structure code for the easy representation of constituent oligosaccharides from glycosaminoglycans

(2008) Roger Lawrence et al.   NATURE METHODS