Article
Engineering, Multidisciplinary
Saddam Heydarov, Musa Aydin, Cagri Faydaci, Suha Tuna, Sadullah Ozturk
Summary: In this study, a low-cost and portable spectrophotometer device capable of analyzing in the visible-near infrared region was designed. The study presented the development of user-friendly device control software based on C#.NET and machine learning algorithms for data classification. The spectrophotometer employed three commercial spectral sensors and achieved high accuracies using Support Vector Machines (SVM) and Convolutional Neural Network (CNN) approaches.
ENGINEERING SCIENCE AND TECHNOLOGY-AN INTERNATIONAL JOURNAL-JESTECH
(2023)
Review
Biotechnology & Applied Microbiology
Zahra Pazhouhnia, Nima Beheshtizadeh, Mojdeh Salehi Namini, Nasrin Lotfibakhshaiesh
Summary: This review discusses the advantages and challenges of portable hand-held bioprinters for in situ tissue regeneration. It covers various tissues that have been investigated using this approach, as well as the design and applications of hand-held bioprinters. The review also highlights the potential of these devices in translating regenerative medicine science from the laboratory to the clinic.
BIOENGINEERING & TRANSLATIONAL MEDICINE
(2022)
Article
Spectroscopy
Lu Hao, Fu Wan-le, Chai Jun, Liu Shuang, Sun Zuo-yu
Summary: The application of handheld X-ray fluorescence spectrometer in analyzing stone cultural relics offers an efficient and non-destructive method for petrochemical composition analysis. It can provide insights into the internal differences in weathering resistance of massive rock mass, as well as indicate rock strata with high water content for evaluation of water stagnation and seepage situations. This tool supports comparative studies of stone cultural relics damages under different climatic and hydrological conditions.
SPECTROSCOPY AND SPECTRAL ANALYSIS
(2022)
Review
Chemistry, Analytical
Philip J. Potts, Mike Sargent
Summary: Hand-held X-ray fluorescence (XRF) instrumentation is commonly used in problem solving applications. In situ measurements provide cheap and rapid results, but interpretations must be careful to avoid misleading outcomes. Understanding the depth of the XRF excited volume, data interpretation near detection limits, and factors affecting uncertainty budget are important for the proper use of XRF data.
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2022)
Article
Chemistry, Analytical
Hyun Soo Kim, Taeha Lee, Jongsu Yun, Gyudo Lee, Yoochan Hong
Summary: A simple Raman spectroscopic method utilizing a silver nanoforest substrate and a handheld Raman spectrometer was developed for the identification of cancer protein biomarkers, achieving successful detection of tiny amounts of proteins. This technique has the potential to facilitate the creation of Raman libraries for cancer biomarkers.
MICROCHEMICAL JOURNAL
(2021)
Article
Geochemistry & Geophysics
Cameron Adams, Michael Dentith, Marco Fiorentini
Summary: The accurate characterization of mafic and ultramafic rocks using a new workflow involving portable energy dispersive X-ray fluorescence (pXRF) and portable visible and near-infrared (pVis-NIR) technologies. The workflow includes six steps: mitigating and identifying compound processing and closure issues, identifying and excluding geochemically heterogeneous samples, relating rocks from similar events, correcting XRF iron data, characterizing lithology and alteration, characterizing fractionation in detail, and identifying and quantifying talc alteration and serpentinization.
GEOCHEMISTRY-EXPLORATION ENVIRONMENT ANALYSIS
(2021)
Article
Biochemical Research Methods
Andre Ahrens, Stefan Zimmermann
Summary: Ion mobility spectrometers are widely used in various applications due to their fast response times and high sensitivity, but can face challenges when dealing with gas mixtures. A miniaturized drift tube IMS coupled with a compact gas chromatograph is proposed to address this issue, reducing chemical cross sensitivities caused by competing gas-phase ionization processes through pre-separation.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Lei Cao, Xiaojin Guo, Ping Mao, Yulin Ren, Zedong Li, Minli You, Jie Hu, Miao Tian, Chunyan Yao, Fei Li, Feng Xu
Summary: A portable digital loop-mediated isothermal amplification (dLAMP) platform was developed, integrating a microscale hydrogel (microgel) array chip, a miniaturized heater, and a hand-held reader for DNA sample partition, amplification, and digital readout. The platform allows for absolute quantification of DNA, showing great potential for nucleic acid point-of-care testing (POCT).
Article
Engineering, Biomedical
Justin Leadbeatter, Jennifer Diffey
Summary: The use of hand-held dental X-ray units is increasing in Australia, with concerns about operator radiation exposure. This study found that attaching a scatter shield to the X-ray unit significantly reduces operator radiation doses, ensuring compliance with legislative requirements and minimizing occupational exposure.
PHYSICAL AND ENGINEERING SCIENCES IN MEDICINE
(2021)
Article
Chemistry, Multidisciplinary
Stelios Chatzimichail, Faraz Rahimi, Aliyah Saifuddin, Andrew J. Surman, Simon D. Taylor-Robinson, Ali Salehi-Reyhani
Summary: Polycyclic aromatic hydrocarbons (PAHs) are considered priority hazardous substances due to their carcinogenic activity and risk to public health. A portable system incorporating a broadband absorption detector has been developed to reliably identify PAHs based on their characteristic spectral profiles, enabling real-time decision making in field settings. This system is capable of detecting and classifying co-eluting and hidden peaks, independent of characteristic retention times, thus mitigating matrix effects and allowing for more sophisticated analytical measurements.
COMMUNICATIONS CHEMISTRY
(2021)
Review
Biochemistry & Molecular Biology
Nur Cebi, Hatice Bekiroglu, Azime Erarslan, Luis Rodriguez-Saona
Summary: Food integrity assurance is a major global challenge, with increasing economically motivated food adulteration and authenticity issues. Effective on-site food analysis technologies, such as FTIR spectroscopy combined with chemometrics, can help in the early detection and prevention of food integrity-related problems. Hand-held and portable FTIR instruments have shown potential in surveilling food quality and safety at critical points of the food supply chain.
Article
Metallurgy & Metallurgical Engineering
N. P. Mabasa, N. Naude, A. M. Garbers-Craig
Summary: An improved methodology is proposed to assess the economic feasibility and effectiveness of recycling MgO-C and Al2O3-MgO-C refractory bricks used in the steelmaking industry. The study examines the use of HH-XRF to distinguish between different oxide-carbon-based refractory bricks, such as MC and AMC bricks. The results show that HH-XRF provides a reliable method for sorting spent MC and AMC bricks quickly.
JOURNAL OF THE SOUTHERN AFRICAN INSTITUTE OF MINING AND METALLURGY
(2023)
Article
Physics, Multidisciplinary
Eugen A. Preoteasa, Daniela Cristea-Stan, Adela C. Scafes, Alexandru Iliescu, Elena S. Preoteasa, Ioana Suciu, Mihaela Chirila, Dan Straja
Summary: Fourteen composites for restorative dentistry and other dental materials were examined using portable XRF spectrometers, measuring the Compton-to-Rayleigh scattering ratio (C/R) for characterization. The C/R ratio, indicating the presence of light and heavy elements, showed potential as an intrinsic quantity specific to dental materials. Newer dental composites generally exhibited higher ratios of light elements and lower levels of heavy elements compared to older ones.
ROMANIAN JOURNAL OF PHYSICS
(2021)
Article
Anthropology
Anno Hein, Agata Dobosz, Peter M. Day, Vassilis Kilikoglou
Summary: Provenance studies of archaeological ceramics using elemental composition reveal information about production and distribution. High-performance laboratory methods like NAA and WDXRF are preferred for precise analysis, while pXRF, despite lower analytical performance, offers advantages in analyzing larger sample sizes. Handheld pXRF systems can provide fast and non-invasive measurements, particularly useful for initial surveys of large ceramic assemblages before selecting samples for further laboratory analysis.
JOURNAL OF ARCHAEOLOGICAL SCIENCE
(2021)
Article
Instruments & Instrumentation
Andrew Ashie, Hong Lei, Banxing Han, Meng Xiong, Hui Yan
Summary: A fast method using a hand-held NIR spectrometer was developed to detect active ingredients in milk thistle extract, with results showing improved calibration performance of selected wavelength variables compared to the whole wavelength variables. Through pre-treatment methods and mathematical models, the active ingredients of silybin, SS, and isosilybin in milk thistle extract were quantified and validated, demonstrating the accuracy and robustness of the proposed method.
INFRARED PHYSICS & TECHNOLOGY
(2021)
Article
Chemistry, Analytical
J. M. Madariaga, J. Aramendia, G. Arana, K. Castro, L. Gomez-Nubla, S. Fdez-Ortiz de Vallejuelo, C. Garcia-Florentino, M. Maguregui, J. A. Manrique, G. Lopez-Reyes, J. Moros, A. Cousin, S. Maurice, A. M. Ollila, R. C. Wiens, F. Rull, J. Laserna, V. Garcia-Baonza, M. B. Madsen, O. Forni, J. Lasue, S. M. Clegg, S. Robinson, P. Bernardi, A. J. Brown, P. Cais, J. Martinez-Frias, P. Beck, S. Bernard, M. H. Bernt, O. Beyssac, E. Cloutis, C. Drouet, G. Dromart, B. Dubois, C. Fabre, O. Gasnault, I. Gontijo, J. R. Johnson, J. Medina, P. -Y. Meslin, G. Montagnac, V. Sautter, S. K. Sharma, M. Veneranda, P. A. Willis
Summary: The aim of this study is to analyze and verify the homogeneity of major mineral samples in the SuperCam calibration targets for proper calibration on Mars. Surface analysis of the targets was conducted using micro-EDXRF imaging and micro-Raman spectroscopy imaging to identify elements with homogeneous distribution and provide uncertainty values for further calibration.
ANALYTICA CHIMICA ACTA
(2022)
Article
Chemistry, Analytical
Jennifer Huidobro, Julene Aramendia, Gorka Arana, Juan Manuel Madariaga
Summary: This article reviews the adaptation of traditional analytical techniques to in situ space exploration, specifically focusing on the geochemical study of Martian surface. Both elemental and molecular analysis techniques used in Mars missions are described. The challenges faced by analytical chemistry in terms of miniaturization, real-time measurements, automation, and reliability under extreme conditions are emphasized.
ANALYTICA CHIMICA ACTA
(2022)
Article
Astronomy & Astrophysics
S. Shkolyar, S. J. Jaret, B. A. Cohen, J. R. Johnson, O. Beyssac, J. M. Madariaga, R. C. Wiens, A. Ollila, S. Holm-Alwmark, Y. Liu
Summary: This article reviews the shock indicators in plagioclase feldspar, with a focus on Raman spectroscopy, and discusses how these indicators can influence the caching decisions for selecting optimal samples. Challenges faced for the success of the Mars Sample Return program include in situ measurements and laboratory studies.
EARTH MOON AND PLANETS
(2022)
Article
Biochemistry & Molecular Biology
Ilaria Costantini, Kepa Castro, Juan Manuel Madariaga, Gorka Arana
Summary: Micro-Raman spectroscopy and micro-energy-dispersive X-ray fluorescence spectroscopy were used to study the Plaiko Zubixe footbridge. The original paint coating and conservation state were evaluated before restoration. The distribution of compounds and original color were determined, and the atmospheric impact on the bridge conservation was highlighted.
Article
Environmental Sciences
Jose Maria Esbri, Carmelo M. Minang, Sofia Rivera, Mercedes Madrid-Illescas, Eva Garcia-Noguero, Ana Gonzalez-Valoys, Maite Maguregui, Hugues Thouin, Fabienne Battaglia-Brunet, Eric Gloaguen, Pablo Leon Higueras
Summary: This study focuses on Sb mobility, its transfer to biota, and its impact on soil health in a semi-arid climate. The research identifies stibnite (Sb2S3) as the primary Sb compound and observes high Sb contents in mining materials and soils. The soil-to-plant transfer of Sb is very low, and most of it remains in a residual fraction, with a negligible amount being leachable. The study suggests that the low annual rainfall rates and the scarcity of oxidized Sb compounds explain the limited Sb mobility and dispersion in the mining area, indicating a low toxicological risk associated with past mining activities.
Article
Physics, Multidisciplinary
Silvia Perez-Diez, Aitor Larranaga, Juan Manuel Madariaga, Maite Maguregui
Summary: The blackening of red cinnabar pigment is traditionally explained by its conversion into black metacinnabar, but there is scarce scientific evidence to support this hypothesis. This study found that the blackening of cinnabar in Pompeian samples is mainly related to the presence of calomel and gypsum crust, rather than the formation of metacinnabar. Laser-based techniques can also result in an amorphous black product, which may lead to false positives in metacinnabar detection.
EUROPEAN PHYSICAL JOURNAL PLUS
(2022)
Article
Environmental Sciences
Euler Gallego-Cartagena, Hector Morillas, Wendy Morgado-Gamero, Fabio Fuentes-Gandara, Victor Vacca-Jimeno, Isabel Salcedo, Juan Manuel Madariaga, Maite Maguregui
Summary: Concerns about air pollution have increased significantly in recent decades, especially in urban areas. The use of biological systems as passive samplers provides information about air pollution to assist decision-making in environmental health and urban planning. This study developed a method using naturally growing subaerial biofilms on building facades as natural passive biomonitors for atmospheric heavy metals pollution. The study employed multianalytical approaches to identify the composition of particulate matter accumulated on the biofilms, distinguishing between metals from the original structure and those from anthropogenic emissions. This methodology can be used as an alternative for rapid screening of atmospheric heavy metals pollution.
Article
Spectroscopy
Imanol Torre-Fdez, Cristina Garcia-Florentino, Jennifer Huidobro, Leire Coloma, Patricia Ruiz-Galende, Julene Aramendia, Kepa Castro, Gorka Arana, Juan Manuel Madariaga
Summary: The presence and geochemical composition of olivine on Mars are important for studying the planet. Raman spectrometers, used in Mars 2020 and future missions, provide new possibilities to determine the Mg/Fe ratios in olivine-bearing rocks. Olivine's presence indicates past volcanic activity on Mars, and its forsterite/fayalite ratio can reveal information about the origin and evolution of the parent magma. This study proposes a new calibration model using Raman spectroscopy, greatly improving the accuracy and uncertainty associated with the forsterite/fayalite ratios compared to previous literature.
JOURNAL OF RAMAN SPECTROSCOPY
(2023)
Article
Crystallography
Silvia Perez-Diez, Cheyenne Bernier, Javier G. Inanez, Maite Maguregui
Summary: This study presents a non-invasive in situ methodology using portable elemental and molecular spectroscopic-based instrumentation to assist provenance studies of archaeological cinnabar pigments. Six cinnabar ores and a pigment from Pompeii were analyzed, and a comparative study of in-situ and laboratory results was conducted. Chemometric data treatment was performed, revealing the need for additional methodologies in the laboratory. However, this methodology was useful for classifying the ores based on mineralogical differences.
Article
Materials Science, Multidisciplinary
Ingrid Fitje Apneseth, Maite Maguregui, Alessandra Vichi, Francesco Caruso
Summary: This study investigates the effect of three commercial cleaning products (Baolin, Centurio, Fulgentin) on shellac-coated mahogany furniture in the Royal Palace of Norway. Non-invasive techniques, such as portable ER-FTIR spectroscopy and colorimetry, are used to assess the chemical composition and color changes of fresh and aged mahogany wood mock-ups. The results suggest that one of the cleaning products may negatively impact the long-term preservation of this furniture collection.
Article
Geography, Physical
Jennifer Huidobro, Julene Aramendia, Gorka Arana, Elisabeth M. Hausrath, Juan Manuel Madariaga
Summary: Raman spectra of gypsum, syngenite, and gorgeyite powders were analyzed at different temperatures. The main bands of the three sulfates shifted towards higher wavenumbers with decreasing temperature, indicating stronger bonds and higher energy. However, the behavior of -OH bands varied depending on the crystal structure acquired at different temperatures. The -OH bands of gypsum became narrower and sharper with decreasing temperature, indicating a more ordered crystalline structure.
ANNALS OF GLACIOLOGY
(2023)
Article
Archaeology
P. Irizar, O. Gomez-Laserna, G. Arana, J. M. Madariaga, I. Martinez-Arkarazo
Summary: This research investigates the potential of agar hydrogels loaded with ionic liquids (ILs) as a sustainable and gentle cleaning method for built heritage conservation. The results demonstrate that ILs can effectively remove iron and copper stains while also inhibiting microbial growth. This study showcases the potential of IL-loaded agar hydrogels as an innovative approach in the field of built heritage conservation.
JOURNAL OF CULTURAL HERITAGE
(2023)
Article
Archaeology
Eugenia Tomasini, Ilaria Costantini, Valeria Careaga, Carlos Rua Landa, Kepa Castro, Juan Manuel Madariaga, Marta Maier, Gabriela Siracusano
Summary: Research on the materiality of Andean Colonial artistic heritage provides insights into the cultural and social history of the region. This study examines a hidden mural painting in a church in Bolivia using interdisciplinary and multi-analytical approaches. The identification of pigments and painting techniques revealed the use of local materials by Andean painters, as well as their adaptation of traditional European practices. This knowledge contributes to the conservation and preservation of similar artworks in the Andean region.
JOURNAL OF CULTURAL HERITAGE
(2023)
Review
Geosciences, Multidisciplinary
Mark A. Sephton, Jonathan S. W. Tan, Jonathan S. Watson, Keyron Hickman-Lewis, Juan M. Madariaga
Summary: The search for organic biomarkers on Mars is a high-priority goal for past, present, and future missions. Thermal extraction is the most popular in situ analysis technique, but it faces challenges when analyzing mineral-organic mixtures. Potential mitigations are suggested for future experiments, which can be used both on Mars and on returned samples on Earth.
JOURNAL OF THE GEOLOGICAL SOCIETY
(2023)
Article
Biochemistry & Molecular Biology
Ilaria Costantini, Julene Aramendia, Nagore Prieto-Taboada, Gorka Arana, Juan Manuel Madariaga, Juan Francisco Ruiz
Summary: In this study, micro-samples from a rock art site in Spain were analyzed to understand the conservation state of the painted panel and to confirm the efficacy of a desalination treatment. Various techniques were used for characterization, revealing the presence of dolomitic limestone, silicon aggregates, aluminosilicates, iron oxides, and sulfate compounds. The analysis also showed evidence of biological activity and the presence of calcium oxalates, which likely contribute to the preservation of the pictographs. The presence of carotenoid pigments and the intentional use of hematite for painting were also identified.
Article
Chemistry, Analytical
Michel Rocha Baqueta, Augusto Cesar Costa-Santos, Ana Paula Rebellato, Gisele Marcondes Luz, Juliana Azevedo Lima Pallone, Federico Marini, Alexsandro Lara Teixeira, Douglas N. Rutledge, Patricia Valderrama
Summary: This study reports the essential element composition of new Brazilian Canephora coffees and applies chemometric tools for analysis. The results demonstrate the suitability of this method for origin and species discrimination based on the inorganic fraction of coffee.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Mengjie Li, Jiapeng Wang, You Zhou, Yang Chen, Lingying Xia
Summary: A novel photoelectrochemical biosensor based on gold nanoparticles and specific structures was developed for highly sensitive detection of mercury ion. The multiple sandwich structures hindered electron supply and light harvesting, resulting in a weakened PEC signal, while the specific structures extinguished the PEC signal, enabling quantitative detection of Hg2+. The sensor exhibited high selectivity and stability, with potential applications in environmental detection, biological analysis, and medical research.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Mohamed A. Korany, Rasha M. Youssef, Marwa A. A. Ragab, Mostafa A. Afify
Summary: A stability-indicating fit-for-purpose method was developed for the determination of HC, TL, and PS in syrup dosage form. The method successfully separated CL from THY and quantified the analytes using HPLC-DAD. The robustness of the method was assessed through statistical analysis and self-validation.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Lingling Lin, Minyu Li, Ping Li, Chenqing Ye, Huanglong Zhuang, Shaohuang Weng, Feng Chen
Summary: This study developed a highly sensitive and selective electrochemical sensor for simultaneous detection of dopamine and uric acid. The sensor exhibited excellent anti-interference and stability, and could accurately measure dopamine and uric acid in human urine samples.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Peifang Chen, Caiyun Jiang, Zhouping Wang, Hong-zhen Lian, Xiaoyuan Ma
Summary: In this study, a high-performance SERS-active aptasensor was successfully developed for the quantitative analysis of AFB1 in cereal grains, which is of great significance in the field of food safety.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
E. Abas, C. Marina-Montes, C. Perez-Marin, J. Puimedon, J. Anzano
Summary: This study conducted a comprehensive measurement of natural and anthropogenic radionuclides in soil, water, and air in different locations around Deception Island in Antarctica. The results revealed significant levels of 210Pb and anthropogenic 137Cs in soil samples near old human settlements and facilities, as well as detectable levels of 137Cs and 60Co in water samples from old hunting areas. The findings also suggested potential resuspension processes based on higher-than-expected air quality results.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Joao Franciso Allochio, Nayara A. dos Santos, Nathalia dos S. Conceicao, Clara S. D. Baptista, Keyller B. Borges, Valdemar Lacerda Jr, Wanderson Roma
Summary: This study developed a fiber spray ionization mass spectrometry (FSI-MS) method, which shows great potential in detecting illicit drugs. Compared with paper spray ionization mass spectrometry (PSI-MS), FSI-MS demonstrates higher sensitivity in COC detection.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Dina A. Ahmed, Ola G. Hussein, Mamdouh R. Rezk, Mohamed Abdelkawy, Yasmin Rostom
Summary: The main goal of this study was to develop two green chromatographic techniques, HPLC and TLC, for the determination of alcaftadine (ALF) in pharmaceutical formulation and biological samples. The developed HPLC technique showed high efficiency and minimal environmental impact, successfully identifying ALF in the presence of its degradate. The TLC method provided a stability indicating study for ALF and was determined to be safe, green, and eco-friendly.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Abdullah Taner Bisgin
Summary: A green, speedy, and handy method for separation and determination of four commonly used food colorants was established using vortex assisted sequential-simultaneous liquid phase micro-extraction (VA-SS-LPME). The method does not require any instrumental chromatographic techniques. The procedure includes sequential separation steps using different extractants and simultaneous UV-vis spectrophotometric determination steps. The method is environmentally friendly and applicable for determination of colorants in food and pharmaceuticals.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Yifan Zhang, Tong Zhang, Wenjing Ba, Li Liu, Yuan Rao, Xiaodan Zhang, Hanhan Zhang, Xiu Jin
Summary: This paper proposes a novel spectral transfer modelling method based on neural network architecture searching for the asymptomatic prediction of Akizuki pear cork spot disorder. The experiments show that the model by this method is more effective, achieving an accuracy of 82.61%.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Krzysztof Greda, Maja Welna, Anna Szymczycha-Madeja, Pawel Pohl
Summary: For the first time, a dispersive micro-solid phase extraction (D-mu SPE) based on graphene oxide was used for the ultrasensitive determination of Cd. With this method, Cd can be efficiently extracted from a mixture of alkali and alkaline earth metals without the need for an elution step. The combination of D-mu SPE and SAGD OES significantly reduces matrix effects and improves the tolerance of Cd to alkali metals. The method shows simplicity in the measurement system and the commercially available nanosorbent used.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
P. K. Fathima Anjila, G. R. Tharani, Anand Sundaramoorthy, Venkat Kumar Shanmugam, Karthikeyan Subramani, Shanmugavel Chinnathambi, Ganesh N. Pandian, Vimala Raghavan, Andrews Nirmala Grace, Singaravelu Ganesan, Mangaiyarkarasi Rajendiran
Summary: This work proposes a rapid and sensitive spectroscopic method for detecting melamine in food products using rare-earth Terbium-doped Graphene Quantum Dots (Tb-GQDs) synthesized by microwave and simple chemical conjugation methods. The synthesized Tb-GQDs show a spherical shape with a size of approximately 6 nm and a quantum yield of 52%. The maximum detection limit for melamine concentration in milk and milk products is found to be 0.31 μM. The dual emitting Tb-GQDs provide a sensitive and effective platform for real-time detection of melamine in food samples, particularly in milk, and show promising potential in the food industry.
MICROCHEMICAL JOURNAL
(2024)
Review
Chemistry, Analytical
Piyush Dey, Mandeep Kaur, Akhil Khajuria, Dilmeet Kaur, Manpreet Singh, Hema Kumari Alajangi, Neha Singla, Gurpal Singh, Ravi Pratap Barnwal
Summary: Environmental issues, such as the uncontrolled release of dangerous pollutants, have significant impacts on human health. Traditional methods for detecting pollutants require specialized personnel and equipment, but nanotechnology has improved the performance of biosensors. This article discusses the use of nanotechnology in pollutant detection and the associated techniques.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Sa Dong, Qiuyun Shi, Lingjun Guan, Yulong Wang, Pengyan Liu, Cunzheng Zhang, Jianguo Feng
Summary: In this study, a highly sensitive indirect competitive chemiluminescence enzyme immunoassay (icCLEIA) method was developed for the determination of sodium pentachlorophenolate (PCP-Na) and its metabolite pentachlorophenol (PCP). The method showed high specificity and affinity with a detection limit of 0.0032 ng/mL for PCP-Na and 0.0192 ng/mL for PCP. The method had no cross reaction with other chlorophenols compounds except for PCP. The average recoveries in chicken, pork and fish samples were 81.3-105.8% with low coefficient of variation (CV).
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Palaniappan Ilayaraja, Murugan Manivannan, Paramasivam Parthiban
Summary: Nirmatrelvir, an antiviral drug used for the treatment of COVID-19, has been recommended by the World Health Organization. We developed an optimized analytical method for the quantification of Nirmatrelvir and its products, with high sensitivity and a wide linear range. The method also meets the requirements for greenness evaluation.
MICROCHEMICAL JOURNAL
(2024)