The anti-cancerous drug doxorubicin decreases the c-di-GMP content in Pseudomonas aeruginosa but promotes biofilm formation

Antimicrobial resistance, respiratory tract infections and role of biofilms in lung infections in cystic fibrosis patients

(2015) Oana Ciofu et al.   ADVANCED DRUG DELIVERY REVIEWS

Cyclic Di-GMP-Regulated Periplasmic Proteolysis of a Pseudomonas aeruginosa Type Vb Secretion System Substrate

(2015) Richard B. Cooley et al.   JOURNAL OF BACTERIOLOGY

Bacterial Signal Transduction by Cyclic Di-GMP and Other Nucleotide Second Messengers

(2015) Regine Hengge et al.   JOURNAL OF BACTERIOLOGY

Urinary tract infections: epidemiology, mechanisms of infection and treatment options

(2015) Ana L. Flores-Mireles et al.   NATURE REVIEWS MICROBIOLOGY

Bactericidal Antibiotics Induce Toxic Metabolic Perturbations that Lead to Cellular Damage

(2015) Peter Belenky et al.   Cell Reports

The Formation of Biofilms byPseudomonas aeruginosa: A Review of the Natural and Synthetic Compounds Interfering with Control Mechanisms

(2015) Tsiry Rasamiravaka et al.   Biomed Research International

The LapG protein plays a role inPseudomonas aeruginosabiofilm formation by controlling the presence of the CdrA adhesin on the cell surface

(2015) Morten Rybtke et al.   MicrobiologyOpen

Pseudomonas aeruginosa Phenotypes Associated With Eradication Failure in Children With Cystic Fibrosis

(2014) Nicole Mayer-Hamblett et al.   CLINICAL INFECTIOUS DISEASES

Formation and dimerization of the phosphodiesterase active site of thePseudomonas aeruginosaMorA, a bi-functional c-di-GMP regulator

(2014) Curtis William Phippen et al.   FEBS LETTERS

The Diguanylate Cyclase SadC Is a Central Player in Gac/Rsm-Mediated Biofilm Formation in Pseudomonas aeruginosa

(2014) J. A. Moscoso et al.   JOURNAL OF BACTERIOLOGY

Diguanylate cyclase NicD-based signalling mechanism of nutrient-induced dispersion byPseudomonas aeruginosa

(2014) Ankita Basu Roy et al.   MOLECULAR MICROBIOLOGY

Inhibition and destruction of Pseudomonas aeruginosa biofilms by antibiotics and antimicrobial peptides

(2014) Sibel Dosler et al.   PEPTIDES

Dispersed cells represent a distinct stage in the transition from bacterial biofilm to planktonic lifestyles

(2014) Song Lin Chua et al.   Nature Communications

Extracellular DNA Shields against Aminoglycosides in Pseudomonas aeruginosa Biofilms

(2013) Wen-Chi Chiang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Optimal dosing regimen of nitric oxide donor compounds for the reduction of Pseudomonas aeruginosa biofilm and isolates from wastewater membranes

(2013) Robert J. Barnes et al.   BIOFOULING

Pseudomonas aeruginosa biofilm: Potential therapeutic targets

(2013) Garima Sharma et al.   BIOLOGICALS

Biologically inspired strategies for combating bacterial biofilms

(2013) Meghan S Blackledge et al.   CURRENT OPINION IN PHARMACOLOGY

The extracellular matrix protectsPseudomonas aeruginosabiofilms by limiting the penetration of tobramycin

(2013) Boo Shan Tseng et al.   ENVIRONMENTAL MICROBIOLOGY

Biofilm Matrix and Its Regulation in Pseudomonas aeruginosa

(2013) Qing Wei et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

NO-Induced Biofilm Dispersion in Pseudomonas aeruginosa Is Mediated by an MHYT Domain-Coupled Phosphodiesterase

(2013) Y. Li et al.   JOURNAL OF BACTERIOLOGY

Bacterial Biofilms: Development, Dispersal, and Therapeutic Strategies in the Dawn of the Postantibiotic Era

(2013) M. Kostakioti et al.   Cold Spring Harbor Perspectives in Medicine

Fluorescence-Based Reporter for Gauging Cyclic Di-GMP Levels in Pseudomonas aeruginosa

(2012) Morten T. Rybtke et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

The metabolically active subpopulation inPseudomonas aeruginosabiofilms survives exposure to membrane-targeting antimicrobials via distinct molecular mechanisms

(2012) Wen-Chi Chiang et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Synergistic antibacterial efficacy of early combination treatment with tobramycin and quorum-sensing inhibitors against Pseudomonas aeruginosa in an intraperitoneal foreign-body infection mouse model

(2012) L. D. Christensen et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Cyclic Diguanylate Inversely Regulates Motility and Aggregation in Clostridium difficile

(2012) E. B. Purcell et al.   JOURNAL OF BACTERIOLOGY

The Phosphodiesterase DipA (PA5017) Is Essential for Pseudomonas aeruginosa Biofilm Dispersion

(2012) A. B. Roy et al.   JOURNAL OF BACTERIOLOGY

Doxorubicin: an update on anticancer molecular action, toxicity and novel drug delivery systems

(2012) Oktay Tacar et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Pyocyanin Promotes Extracellular DNA Release in Pseudomonas aeruginosa

(2012) Theerthankar Das et al.   PLoS One

Dispersion by Pseudomonas aeruginosa requires an unusual posttranslational modification of BdlA

(2012) O. E. Petrova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Unique Biofilm Signature, Drug Susceptibility and Decreased Virulence in Drosophila through the Pseudomonas aeruginosa Two-Component System PprAB

(2012) Sophie de Bentzmann et al.   PLoS Pathogens

The Second Skin: Ecological Role of Epibiotic Biofilms on Marine Organisms

(2012) Martin Wahl et al.   Frontiers in Microbiology

Identification of a Novel Benzimidazole That Inhibits Bacterial Biofilm Formation in a Broad-Spectrum Manner

(2011) Karthik Sambanthamoorthy et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Pseudomonas aeruginosa Psl polysaccharide reduces neutrophil phagocytosis and the oxidative response by limiting complement-mediated opsonization

(2011) Meenu Mishra et al.   CELLULAR MICROBIOLOGY

Phenotypes of Non-Attached Pseudomonas aeruginosa Aggregates Resemble Surface Attached Biofilm

(2011) Morten Alhede et al.   PLoS One

The PprA-PprB two-component system activates CupE, the first non-archetypal Pseudomonas aeruginosa chaperone-usher pathway system assembling fimbriae

(2010) Caroline Giraud et al.   ENVIRONMENTAL MICROBIOLOGY

A liquid chromatography-coupled tandem mass spectrometry method for quantitation of cyclic di-guanosine monophosphate

(2010) Christian Spangler et al.   JOURNAL OF MICROBIOLOGICAL METHODS

Pseudomonas aeruginosauses a cyclic-di-GMP-regulated adhesin to reinforce the biofilm extracellular matrix

(2010) Bradley R. Borlee et al.   MOLECULAR MICROBIOLOGY

YfiBNR Mediates Cyclic di-GMP Dependent Small Colony Variant Formation and Persistence in Pseudomonas aeruginosa

(2010) Jacob G. Malone et al.   PLoS Pathogens

Differential expression analysis for sequence count data

(2010) Simon Anders et al.   GENOME BIOLOGY

SiaA and SiaD are essential for inducing autoaggregation as a specific response to detergent stress inPseudomonas aeruginosa

(2009) Janosch Klebensberger et al.   ENVIRONMENTAL MICROBIOLOGY

Nitric Oxide Signaling in Pseudomonas aeruginosa Biofilms Mediates Phosphodiesterase Activity, Decreased Cyclic Di-GMP Levels, and Enhanced Dispersal

(2009) N. Barraud et al.   JOURNAL OF BACTERIOLOGY

Principles of c-di-GMP signalling in bacteria

(2009) Regine Hengge   NATURE REVIEWS MICROBIOLOGY

Assembly and Development of the Pseudomonas aeruginosa Biofilm Matrix

(2009) Luyan Ma et al.   PLoS Pathogens

Roles of type IV pili, flagellum-mediated motility and extracellular DNA in the formation of mature multicellular structures inPseudomonas aeruginosabiofilms

(2008) Kim B. Barken et al.   ENVIRONMENTAL MICROBIOLOGY

Phosphorylation-Independent Regulation of the Diguanylate Cyclase WspR

(2008) Nabanita De et al.   PLOS BIOLOGY