Initial exploration of a novel fusion protein, IL-4/IL-34/IL-10, which promotes cardiac allograft survival mice through alloregulation

Establishment of Chimerism and Organ Transplant Tolerance in Laboratory Animals: Safety and Efficacy of Adaptation to Humans

(2022) Robert Lowsky et al.   Frontiers in Immunology

G-CSF promotes alloregulatory function of MDSCs through a c-Kit dependent mechanism

(2021) Young S. Lee et al.   CELLULAR IMMUNOLOGY

Myeloid‐derived suppressor cells expand after transplantation and their augmentation increases graft survival

(2020) Young S. Lee et al.   AMERICAN JOURNAL OF TRANSPLANTATION

IL-10 attenuates OxPCs-mediated lipid metabolic responses in ischemia reperfusion injury

(2020) Ashim K. Bagchi et al.   Scientific Reports

Effect of IL-34 on T helper 17 cell proliferation and IL-17 secretion by peripheral blood mononuclear cells from rheumatoid arthritis patients

(2020) Xin Li et al.   Scientific Reports

Myeloid-derived suppressor cells are bound and inhibited by anti-thymocyte globulin

(2019) Young Suk Lee et al.   Innate Immunity

Costimulation Blockade in Kidney Transplant Recipients

(2019) Marieke van der Zwan et al.   DRUGS

Biology and therapeutic potential of interleukin-10

(2019) Margarida Saraiva et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-10 induces an immune repressor pathway in sepsis by promoting S100A9 nuclear localization and MDSC development

(2018) Isatou Bah et al.   CELLULAR IMMUNOLOGY

Tolerance induction in HLA disparate living donor kidney transplantation by facilitating cell-enriched donor stem cell Infusion: The importance of durable chimerism

(2018) Joseph R. Leventhal et al.   HUMAN IMMUNOLOGY

IL-34 and CSF-1 display an equivalent macrophage differentiation ability but a different polarization potential

(2018) Sonia Boulakirba et al.   Scientific Reports

Virotherapy-recruited PMN-MDSC infiltration of mesothelioma blocks antitumor CTL by IL-10-mediated dendritic cell suppression

(2018) Zhiwu Tan et al.   OncoImmunology

Myeloid-Derived Suppressor Cells and their Potential Application in Transplantation

(2017) Joseph R. Scalea et al.   TRANSPLANTATION

Computer-aided designing of immunosuppressive peptides based on IL-10 inducing potential

(2017) Gandharva Nagpal et al.   Scientific Reports

Belatacept and Long-Term Outcomes in Kidney Transplantation

(2016) Flavio Vincenti et al.   NEW ENGLAND JOURNAL OF MEDICINE

Chimerism, Graft Survival, and Withdrawal of Immunosuppressive Drugs in HLA Matched and Mismatched Patients After Living Donor Kidney and Hematopoietic Cell Transplantation

(2015) J. D. Scandling et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Fusion Proteins for Half-Life Extension of Biologics as a Strategy to Make Biobetters

(2015) William R. Strohl   BIODRUGS

M-CSF and GM-CSF Receptor Signaling Differentially Regulate Monocyte Maturation and Macrophage Polarization in the Tumor Microenvironment

(2015) E. Van Overmeire et al.   CANCER RESEARCH

Interleukin-10 paradox: A potent immunoregulatory cytokine that has been difficult to harness for immunotherapy

(2015) Ankit Saxena et al.   CYTOKINE

Tacrolimus for the prevention and treatment of rejection of solid organ transplants

(2015) Joseph R. Scalea et al.   Expert Review of Clinical Immunology

IL-34 is a Treg-specific cytokine and mediates transplant tolerance

(2015) Séverine Bézie et al.   JOURNAL OF CLINICAL INVESTIGATION

Abrogation of Renal Allograft Tolerance in MGH Miniature Swine: The Role of Intra-Graft and Peripheral Factors in Long-Term Tolerance

(2014) J. R. Scalea et al.   AMERICAN JOURNAL OF TRANSPLANTATION

HLA-Mismatched Renal Transplantation without Maintenance Immunosuppression

(2013) Tatsuo Kawai et al.   NEW ENGLAND JOURNAL OF MEDICINE

STAT1-regulated lung MDSC-like cells produce IL-10 and efferocytose apoptotic neutrophils with relevance in resolution of bacterial pneumonia

(2012) S L Poe et al.   Mucosal Immunology

Chimerism and Tolerance Without GVHD or Engraftment Syndrome in HLA-Mismatched Combined Kidney and Hematopoietic Stem Cell Transplantation

(2012) J. Leventhal et al.   Science Translational Medicine

A synthetic peptide homologous to IL-10 functional domain induces monocyte differentiation to TGF-β+ tolerogenic dendritic cells

(2011) Mercedes N. López et al.   IMMUNOBIOLOGY

Interleukin-10 repletion suppresses pro-inflammatory cytokines and decreases liver pathology without altering viral replication in murine cytomegalovirus (MCMV)-infected IL-10 knockout mice

(2010) Yajarayma J. Tang-Feldman et al.   INFLAMMATION RESEARCH

IL-35-mediated induction of a potent regulatory T cell population

(2010) Lauren W Collison et al.   NATURE IMMUNOLOGY

HLA-Mismatched Renal Transplantation without Maintenance Immunosuppression

(2008) Tatsuo Kawai et al.   NEW ENGLAND JOURNAL OF MEDICINE