Tbx1 orchestrates an immune niche that safeguards a broken heart

Lymphatic endothelial transcription factor Tbx1 promotes an immunosuppressive microenvironment to facilitate post-myocardial infarction repair

(2023) Wenfeng Wang et al.   Immunity

T cells specific for α-myosin drive immunotherapy-related myocarditis

(2022) Margaret L. Axelrod et al.   NATURE

VEGF-C-driven lymphatic drainage enables immunosurveillance of brain tumours

(2020) Eric Song et al.   NATURE

Laminar flow downregulates Notch activity to promote lymphatic sprouting

(2017) Dongwon Choi et al.   JOURNAL OF CLINICAL INVESTIGATION

Cardiac lymphatics are heterogeneous in origin and respond to injury

(2015) Linda Klotz et al.   NATURE

Notch-dependent VEGFR3 upregulation allows angiogenesis without VEGF–VEGFR2 signalling

(2012) Rui Benedito et al.   NATURE

Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and Treg cells

(2011) Andrea Facciabene et al.   NATURE

Tbx1 regulatesVegfr3and is required for lymphatic vessel development

(2010) Li Chen et al.   JOURNAL OF CELL BIOLOGY