Characterization of genome-reduced Bacillus subtilis strains and their application for the production of guanosine and thymidine

NADH plays the vital role for chiral pure D-(−)-2,3-butanediol production inBacillus subtilisunder limited oxygen conditions

(2014) Jing Fu et al.   BIOTECHNOLOGY AND BIOENGINEERING

Chassis organism fromCorynebacterium glutamicum- a top-down approach to identify and delete irrelevant gene clusters

(2014) Simon Unthan et al.   Biotechnology Journal

13C-metabolic flux analysis in heterologous cellulase production by Bacillus subtilis genome-reduced strain

(2014) Yoshihiro Toya et al.   JOURNAL OF BIOTECHNOLOGY

The rebalanced pathway significantly enhances acetoin production by disruption of acetoin reductase gene and moderate-expression of a new water-forming NADH oxidase in Bacillus subtilis

(2014) Xian Zhang et al.   METABOLIC ENGINEERING

A reduced genome decreases the host carrying capacity for foreign DNA

(2014) Yuya Akeno et al.   Microbial Cell Factories

Levels of Germination Proteins in Bacillus subtilis Dormant, Superdormant, and Germinating Spores

(2014) Yan Chen et al.   PLoS One

Construction of a Prophage-Free Variant of Corynebacterium glutamicum ATCC 13032 for Use as a Platform Strain for Basic Research and Industrial Biotechnology

(2013) Meike Baumgart et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Genetic manipulations restored the growth fitness of reduced-genome Escherichia coli

(2013) Yasutaka Hirokawa et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Establishment of a Markerless Mutation Delivery System in Bacillus subtilis Stimulated by a Double-Strand Break in the Chromosome

(2013) Ting Shi et al.   PLoS One

An efficient transformation method for Bacillus subtilis DB104

(2012) Ljubica Vojcic et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Streamlining genomes: toward the generation of simplified and stabilized microbial systems

(2012) Audrey Leprince et al.   CURRENT OPINION IN BIOTECHNOLOGY

High external pH enables more efficient secretion of alkaline α-amylase AmyK38 by Bacillus subtilis

(2012) Kenji Manabe et al.   Microbial Cell Factories

Combined Effect of Improved Cell Yield and Increased Specific Productivity Enhances Recombinant Enzyme Production in Genome-Reduced Bacillus subtilis Strain MGB874

(2011) Kenji Manabe et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Grand Challenge Commentary: Chassis cells for industrial biochemical production

(2010) Claudia E Vickers et al.   Nature Chemical Biology

Genome-minimized Streptomyces host for the heterologous expression of secondary metabolism

(2010) M. Komatsu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Engineering of a genome-reduced host: practical application of synthetic biology in the overproduction of desired secondary metabolites

(2010) Hong Gao et al.   Protein & Cell

Fermentative Production of Thymidine by a Metabolically Engineered Escherichia coli Strain

(2009) H. C. Lee et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Considerations for the design and construction of a synthetic platform cell for biotechnological applications

(2009) P.L. Foley et al.   BIOTECHNOLOGY AND BIOENGINEERING

Transcriptome analysis guided metabolic engineering of Bacillus subtilis for riboflavin production

(2009) Shuobo Shi et al.   METABOLIC ENGINEERING

Metabolic engineering of a reduced-genome strain of Escherichia coli for L-threonine production

(2009) Jun Lee et al.   Microbial Cell Factories

The Organization of the Bacterial Genome

(2008) Eduardo P.C. Rocha   Annual Review of Genetics

Enhanced Recombinant Protein Productivity by Genome Reduction in Bacillus subtilis

(2008) T. Morimoto et al.   DNA RESEARCH

Superpositioning of Deletions Promotes Growth of Escherichia coli with a Reduced Genome

(2008) H. Mizoguchi et al.   DNA RESEARCH

Maintenance metabolism and carbon fluxes in Bacillus species

(2008) Simon Tännler et al.   Microbial Cell Factories

High-performance liquid chromatography determination of 5-methyl-2′-deoxycytidine, 2′-deoxycytidine, and other deoxynucleosides and nucleosides in DNA digests

(2007) Armando Alcázar Magaña et al.   ANALYTICAL BIOCHEMISTRY