Homozygous variants in CDC23 cause female infertility characterized by oocyte maturation defects

The mechanism of acentrosomal spindle assembly in human oocytes

(2022) Tianyu Wu et al.   SCIENCE

CENP-F-dependent DRP1 function regulates APC/C activity during oocyte meiosis I

(2022) Cheng-Jie Zhou et al.   Nature Communications

A prometaphase mechanism of securin destruction is essential for meiotic progression in mouse oocytes

(2021) Christopher Thomas et al.   Nature Communications

ASTL is mutated in female infertility

(2021) Sateesh Maddirevula et al.   HUMAN GENETICS

Bi-allelic Missense Pathogenic Variants in TRIP13Cause Female Infertility Characterized by Oocyte Maturation Arrest

(2020) Zhihua Zhang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Cell division cycle 23 is required for mouse oocyte meiotic maturation

(2020) Qian Zhou et al.   FASEB JOURNAL

Biallelic mutations in CDC20 cause female infertility characterized by abnormalities in oocyte maturation and early embryonic development

(2020) Lin Zhao et al.   Protein & Cell

Mutations in NLRP2 and NLRP5 cause female infertility characterised by early embryonic arrest

(2019) Jian Mu et al.   JOURNAL OF MEDICAL GENETICS

Novel mutations in PATL2: expanding the mutational spectrum and corresponding phenotypic variability associated with female infertility

(2019) Ling Wu et al.   JOURNAL OF HUMAN GENETICS

The Arabidopsis anaphase‐promoting complex/cyclosome subunit 8 is required for male meiosis

(2019) Rong‐Yan Xu et al.   NEW PHYTOLOGIST

A liquid-like spindle domain promotes acentrosomal spindle assembly in mammalian oocytes

(2019) Chun So et al.   SCIENCE

Segregating Chromosomes in the Mammalian Oocyte

(2018) Aleksandar I. Mihajlović et al.   CURRENT BIOLOGY

Regulation of chromosome segregation in oocytes and the cellular basis for female meiotic errors

(2017) Jessica Greaney et al.   HUMAN REPRODUCTION UPDATE

Maternal age-dependent APC/C-mediated decrease in securin causes premature sister chromatid separation in meiosis II

(2017) Ibtissem Nabti et al.   Nature Communications

Mutations inTUBB8cause a multiplicity of phenotypes in human oocytes and early embryos

(2016) Ruizhi Feng et al.   JOURNAL OF MEDICAL GENETICS

Mutations in TUBB8 and Human Oocyte Meiotic Arrest

(2016) Ruizhi Feng et al.   NEW ENGLAND JOURNAL OF MEDICINE

The APC/C in female mammalian meiosis I

(2013) Hayden Homer   REPRODUCTION

APC15 mediates CDC20 autoubiquitylation by APC/CMCC and disassembly of the mitotic checkpoint complex

(2012) Kristina Uzunova et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

CDC23 regulates cancer cell phenotype and is overexpressed in papillary thyroid cancer

(2011) Lisa Zhang et al.   ENDOCRINE-RELATED CANCER

APC15 drives the turnover of MCC-CDC20 to make the spindle assembly checkpoint responsive to kinetochore attachment

(2011) Jörg Mansfeld et al.   NATURE CELL BIOLOGY

Cubism and the cell cycle: the many faces of the APC/C

(2011) Jonathon Pines   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Regulation of APC/C Activity in Oocytes by a Bub1-Dependent Spindle Assembly Checkpoint

(2009) Barry E. McGuinness et al.   CURRENT BIOLOGY

Role of cleavage by separase of the Rec8 kleisin subunit of cohesin during mammalian meiosis I

(2009) N. R. Kudo et al.   JOURNAL OF CELL SCIENCE