Considering hormones as sex- and gender-related factors in biomedical research: Challenging false dichotomies and embracing complexity

Fighting cichlids: An integrated multimodal analysis to understand female and male aggression in Cichlasoma dimerus

(2023) María Florencia Scaia et al.   HORMONES AND BEHAVIOR

Mouse spontaneous behavior reflects individual variation rather than estrous state

(2023) Dana Rubi Levy et al.   CURRENT BIOLOGY

Estrogen Receptor Gene Polymorphism as a Possible Genetic Risk Factor for Treatment Response in ER-Positive Breast Cancer Patients

(2022) Nasr M. A. Allahloubi et al.   BIOCHEMICAL GENETICS

Sex, Gender and Health: Mapping the Landscape of Research and Policy

(2022) Lorraine Greaves et al.   International Journal of Environmental Research and Public Health

Elevated prolactin secretion during proestrus in mice: Absence of a defined surge

(2022) Hollian R. Phillipps et al.   JOURNAL OF NEUROENDOCRINOLOGY

An analysis of neuroscience and psychiatry papers published from 2009 and 2019 outlines opportunities for increasing discovery of sex differences

(2022) Rebecca K. Rechlin et al.   Nature Communications

Transcending the Male–Female Binary in Biomedical Research: Constellations, Heterogeneity, and Mechanism When Considering Sex and Gender

(2022) Stacey A. Ritz et al.   International Journal of Environmental Research and Public Health

Narcissism moderates the association between basal testosterone and generosity in men

(2022) Anna Z. Czarna et al.   HORMONES AND BEHAVIOR

Testosterone, cortisol, and criminal behavior in men and women

(2022) Todd A. Armstrong et al.   HORMONES AND BEHAVIOR

The evolution and polymorphism of mono-amino acid repeats in androgen receptor and their regulatory role in health and disease

(2022) Attila Meszaros et al.   Frontiers in Medicine

Androgen receptors immunoreactivity in the rat brain of males with same-sex preference

(2022) Alonso Fernández-Guasti et al.   HORMONES AND BEHAVIOR

Ovarian hormones in relation to naturally cycling women's conception risk: Empirical evidence and implications for behavioral endocrinology

(2022) Tran Dinh et al.   HORMONES AND BEHAVIOR

New Insights into Testosterone Biosynthesis: Novel Observations from HSD17B3 Deficient Mice

(2022) Ben M. Lawrence et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The role of vitamin D in autoimmune diseases: could sex make the difference?

(2021) Maria Luisa Dupuis et al.   Biology of Sex Differences

Dump the “dimorphism”: Comprehensive synthesis of human brain studies reveals few male-female differences beyond size

(2021) Lise Eliot et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Androgen receptor gene microsatellite polymorphism is associated with muscle mass and strength in bodybuilders and power athlete status

(2021) João Paulo L. F. Guilherme et al.   ANNALS OF HUMAN BIOLOGY

Individual variation of follicular phase changes in endothelial function across two menstrual cycles

(2021) Kaitlyn R. Liu et al.   EXPERIMENTAL PHYSIOLOGY

The association between estrogen receptor 2 gene polymorphism and complexity of coronary artery disease: an analysis in elective percutaneous coronary intervention patients

(2021) Farzaneh Foroughinia et al.   BMC Cardiovascular Disorders

Estrogen Receptor 1 Gene rs22346939 and rs9340799 Variants are Associated with Major Depressive Disorder and its Clinical Features

(2021) Filiz Ozsoy et al.   CURRENT NEUROVASCULAR RESEARCH

Classic and Novel Sex Hormone Binding Globulin Effects on the Cardiovascular System in Men

(2021) Carla Basualto-Alarcón et al.   International Journal of Endocrinology

Estradiol induces allosteric coupling and partitioning of sex-hormone-binding globulin monomers among conformational states

(2021) Ravi Jasuja et al.   iScience

A 10-year longitudinal evaluation of science policy interventions to promote sex and gender in health research

(2021) Jenna Haverfield et al.   Health Research Policy and Systems

Roles of Oxytocin in Stress Responses, Allostasis and Resilience

(2021) Yuki Takayanagi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A finding of sex similarities rather than differences in COVID-19 outcomes

(2021) Heather Shattuck-Heidorn et al.   NATURE

Sex difference analyses under scrutiny

(2021) Colby J Vorland   eLife

Reporting and misreporting of sex differences in the biological sciences

(2021) Yesenia Garcia-Sifuentes et al.   eLife

High expression of estrogen receptor alpha and aromatase in glial tumor cells is associated with gender-independent survival benefits in glioblastoma patients

(2020) Lisa Stefanie Hönikl et al.   JOURNAL OF NEURO-ONCOLOGY

A 10-year follow-up study of sex inclusion in the biological sciences

(2020) Nicole C Woitowich et al.   eLife

Impact of the menstrual cycle on peripheral vascular function in premenopausal women: systematic review & meta-analysis.

(2020) Jennifer S Williams et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Menopause Transition and Cardiovascular Disease Risk: Implications for Timing of Early Prevention: A Scientific Statement From the American Heart Association

(2020) Samar R. El Khoudary et al.   CIRCULATION

Androgen receptor gene polymorphism and sexual function in midlife women

(2019) Barbara Sutter et al.   ARCHIVES OF GYNECOLOGY AND OBSTETRICS

Impact of estrogens in males and androgens in females

(2019) Stephen R. Hammes et al.   JOURNAL OF CLINICAL INVESTIGATION

A critical role for estrogen signaling in penis development

(2019) Luke C. Govers et al.   FASEB JOURNAL

Are hormones a “female problem” for animal research?

(2019) Rebecca M. Shansky   SCIENCE

Sex-specific estrogen levels and reference intervals from infancy to late adulthood determined by LC-MS/MS

(2019) Hanne Frederiksen et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Ten common statistical mistakes to watch out for when writing or reviewing a manuscript

(2019) Tamar R Makin et al.   eLife

Vitamin D and Reproductive Hormones Across the Menstrual Cycle

(2019) Q E Harmon et al.   HUMAN REPRODUCTION

Sex and Gender Differences Research Design for Basic, Clinical and Population Studies: Essentials for Investigators

(2018) Janet W Rich-Edwards et al.   ENDOCRINE REVIEWS

Rapid effects of estradiol on aggression depend on genotype in a species with an estrogen receptor polymorphism

(2018) Jennifer R. Merritt et al.   HORMONES AND BEHAVIOR

Feminist science: who needs it?

(2018) Cordelia Fine   LANCET

Sexually Dimorphic Effects of Aromatase on Neurobehavioral Responses

(2018) Dusti A. Shay et al.   Frontiers in Molecular Neuroscience

Muscle Androgen Receptor Content but Not Systemic Hormones Is Associated With Resistance Training-Induced Skeletal Muscle Hypertrophy in Healthy, Young Men

(2018) Robert W. Morton et al.   Frontiers in Physiology

A Reappraisal of Testosterone’s Binding in Circulation: Physiological and Clinical Implications

(2017) Anna L Goldman et al.   ENDOCRINE REVIEWS

Polymorphisms in sex steroid receptors: From gene sequence to behavior

(2017) Donna L. Maney   FRONTIERS IN NEUROENDOCRINOLOGY

Estrogen receptor α gene polymorphism and vascular complications in girls with type 1 diabetes mellitus

(2017) Bartosz Słomiński et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Individual prolactin reactivity modulates response of nucleus accumbens to erotic stimuli during acute cannabis intoxication: an fMRI pilot study

(2017) R. Androvicova et al.   PSYCHOPHARMACOLOGY

Sex Reporting in Preclinical Microbiological and Immunological Research

(2017) Tanvi Potluri et al.   mBio

Regulation of Bone Metabolism by Sex Steroids

(2017) Sundeep Khosla et al.   Cold Spring Harbor Perspectives in Medicine

The polymorphism of estrogen receptor α is important for metabolic consequences associated with menopause

(2016) Jarosław Pinkas et al.   Endokrynologia Polska

Studying both sexes: a guiding principle for biomedicine

(2016) Janine Austin Clayton   FASEB JOURNAL

Plasma steroid-binding proteins: primary gatekeepers of steroid hormone action

(2016) Geoffrey L Hammond   JOURNAL OF ENDOCRINOLOGY

Smoking, alcohol and caffeine in relation to two hormonal indicators of ovarian age during the reproductive years

(2016) J. Kline et al.   MATURITAS

Aromatase: Contributions to Physiology and Disease in Women and Men

(2016) Jennifer Blakemore et al.   PHYSIOLOGY

Female rats are not more variable than male rats: a meta-analysis of neuroscience studies

(2016) Jill B. Becker et al.   Biology of Sex Differences

Rapid Effects of Estradiol on Aggression in Birds and Mice: The Fast and the Furious: Fig. 1

(2015) Sarah A. Heimovics et al.   INTEGRATIVE AND COMPARATIVE BIOLOGY

Opinion: Sex inclusion in basic research drives discovery: Fig. 1.

(2015) Sabra L. Klein et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of gendered behavior on testosterone in women and men

(2015) Sari M. van Anders et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Testosterone in women—the clinical significance

(2015) Susan R Davis et al.   Lancet Diabetes & Endocrinology

Variation in Prolactin Is Related to Variation in Sexual Behavior and Contact Affiliation

(2015) Charles T Snowdon et al.   PLoS One

Estrogen receptor-alpha polymorphism in patients with and without degenerative disease of the temporomandibular joint

(2014) Melissa Stemig et al.   CRANIO-THE JOURNAL OF CRANIOMANDIBULAR PRACTICE

Activation of the Hypothalamic-Pituitary-Gonadal Axis in Infancy: Minipuberty

(2014) Tanja Kuiri-Hänninen et al.   Hormone Research in Paediatrics

Estrogen receptor α gene PvuII polymorphism and coronary artery disease: a meta-analysis of 21 studies

(2014) Jie Ding et al.   Journal of Zhejiang University-SCIENCE B

Policy: NIH to balance sex in cell and animal studies

(2014) Janine A. Clayton et al.   NATURE

Female mice liberated for inclusion in neuroscience and biomedical research

(2014) Brian J. Prendergast et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Early predictive biomarkers for postpartum depression point to a role for estrogen receptor signaling

(2014) D. Mehta et al.   PSYCHOLOGICAL MEDICINE

The effect of physical activity across the menstrual cycle on reproductive function

(2013) Katherine A. Ahrens et al.   ANNALS OF EPIDEMIOLOGY

First steps for integrating sex and gender considerations into basic experimental biomedical research

(2013) Stacey A. Ritz et al.   FASEB JOURNAL

The effect of combined oral contraception on testosterone levels in healthy women: a systematic review and meta-analysis

(2013) Y. Zimmerman et al.   HUMAN REPRODUCTION UPDATE

Androgen receptor gene polymorphism and polycystic ovary syndrome

(2012) Lawrence H. Lin et al.   INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS

Local oestrogenic/androgenic balance in the cerebral vasculature

(2011) D. N. Krause et al.   Acta Physiologica

Short-Term Interaction between Dogs and Their Owners: Effects on Oxytocin, Cortisol, Insulin and Heart Rate—An Exploratory Study

(2011) Linda Handlin et al.   ANTHROZOOS

Using Polymorphisms in FKBP5 to Define Biologically Distinct Subtypes of Posttraumatic Stress Disorder

(2011) Divya Mehta   ARCHIVES OF GENERAL PSYCHIATRY

Diverse Roles for Sex Hormone-Binding Globulin in Reproduction

(2011) G. L. Hammond   BIOLOGY OF REPRODUCTION

Independent and Additive Contributions of Postvictory Testosterone and Social Experience to the Development of the Winner Effect

(2011) Matthew J. Fuxjager et al.   ENDOCRINOLOGY

Maternal tendencies in women are associated with estrogen levels and facial femininity

(2011) Miriam J. Law Smith et al.   HORMONES AND BEHAVIOR

Baby cries and nurturance affect testosterone in men

(2011) Sari M. van Anders et al.   HORMONES AND BEHAVIOR

Follicle-stimulating hormone levels in female workers exposed to urban pollutants

(2011) Manuela Ciarrocca et al.   INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH

Exercise lowers estrogen and progesterone levels in premenopausal women at high risk of breast cancer

(2011) D. A. Kossman et al.   JOURNAL OF APPLIED PHYSIOLOGY

Testosterone Reference Ranges in Normally Cycling Healthy Premenopausal Women

(2011) Glenn D. Braunstein et al.   Journal of Sexual Medicine

Molecular biology of androgen insensitivity

(2011) Jarmo Jääskeläinen   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The Trouble with Sex Differences

(2011) Lise Eliot   NEURON

Diets and Hormonal Levels in Postmenopausal Women With or Without Breast Cancer

(2011) Mylène Aubertin-Leheudre et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Beyond a catalogue of differences: A theoretical frame and good practice guidelines for researching sex/gender in human health

(2011) Kristen W. Springer et al.   SOCIAL SCIENCE & MEDICINE

The role of the estrogen receptor α in the medial amygdala and ventromedial nucleus of the hypothalamus in social recognition, anxiety and aggression

(2010) Thierry Spiteri et al.   BEHAVIOURAL BRAIN RESEARCH

Roles of α- and β-estrogen receptors in mouse social recognition memory: Effects of gender and the estrous cycle

(2010) G. Sánchez-Andrade et al.   HORMONES AND BEHAVIOR

Sex hormone-binding globulin in osteoporosis

(2010) Emmanuel Hoppé et al.   JOINT BONE SPINE

Optimization and prevalidation of the in vitro ERα CALUX method to test estrogenic and antiestrogenic activity of compounds

(2010) Bart van der Burg et al.   REPRODUCTIVE TOXICOLOGY

Optimization and prevalidation of the in vitro AR CALUX method to test androgenic and antiandrogenic activity of compounds

(2010) Bart van der Burg et al.   REPRODUCTIVE TOXICOLOGY

The role of testosterone in women

(2009) Nick Panay et al.   CLIMACTERIC

History of Aromatase: Saga of an Important Biological Mediator and Therapeutic Target

(2009) R. J. Santen et al.   ENDOCRINE REVIEWS

Testosterone release and social context: When it occurs and why

(2009) Erin D. Gleason et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Vascular Endothelial Estrogen Receptor α Is Modulated by Estrogen Status and Related to Endothelial Function and Endothelial Nitric Oxide Synthase in Healthy Women

(2009) Kathleen M. Gavin et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Salivary testosterone, cortisol, and progesterone: Two-week stability, interhormone correlations, and effects of time of day, menstrual cycle, and oral contraceptive use on steroid hormone levels

(2009) Scott H. Liening et al.   PHYSIOLOGY & BEHAVIOR

Dominance, Politics, and Physiology: Voters' Testosterone Changes on the Night of the 2008 United States Presidential Election

(2009) Steven J. Stanton et al.   PLoS One

Gender differences in financial risk aversion and career choices are affected by testosterone

(2009) P. Sapienza et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Testosterone responsiveness to winning and losing experiences in female soccer players

(2009) T. Oliveira et al.   PSYCHONEUROENDOCRINOLOGY

Chewing gum has large effects on salivary testosterone, estradiol, and secretory immunoglobulin A assays in women and men

(2009) Sari M. van Anders   PSYCHONEUROENDOCRINOLOGY

Luteinizing hormone (LH) levels in male workers exposed to urban stressors

(2009) Enrico Tomao et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Follicle-stimulating hormone levels in male workers exposed to urban chemical, physical, and psychosocial stressors

(2009) G Tomei et al.   TOXICOLOGY AND INDUSTRIAL HEALTH