N6-methyladenosine demethylase FTO related to hyperandrogenism in PCOS via AKT pathway

Expression of Serum PSA, Nesfatin-1, and AMH in Patients with Polycystic Ovary Syndrome

(2022) Yan Wang et al.   CELLULAR AND MOLECULAR BIOLOGY

Candidate genes for polycystic ovary syndrome are regulated by TGFβ in the bovine foetal ovary

(2022) Rafiatu Azumah et al.   HUMAN REPRODUCTION

Characterization of altered microRNAs related to different phenotypes of polycystic ovarian syndrome (PCOS) in serum, follicular fluid, and cumulus cells

(2022) Hanieh Motahari Rad et al.   Taiwanese Journal of Obstetrics & Gynecology

Correlation between steroid levels in follicular fluid and hormone synthesis related substances in its exosomes and embryo quality in patients with polycystic ovary syndrome

(2021) Li Yu et al.   Reproductive Biology and Endocrinology

N6-methyladenosine Demethylase FTO Induces the Dysfunctions of Ovarian Granulosa Cells by Upregulating Flotillin 2

(2021) Li Zhou et al.   Reproductive Sciences

The m6A mRNA demethylase FTO in granulosa cells retards FOS-dependent ovarian aging

(2021) Zhong-xin Jiang et al.   Cell Death & Disease

Differences in expression of genes related to steroidgenesis in abdominal subcutaneous adipose tissue of pregnant women with and without PCOS; a case control study

(2021) Neda Emami et al.   BMC Pregnancy and Childbirth

Up-regulated FHL2 inhibits ovulation through interacting with androgen receptor and ERK1/2 in polycystic ovary syndrome

(2020) Ruiqiong Zhou et al.   EBioMedicine

Depletion of exosomal circLDLR in follicle fluid derepresses miR-1294 function and inhibits estradiol production via CYP19A1 in polycystic ovary syndrome

(2020) Xin Huang et al.   Aging-US

Decreased expression of m6A demethylase FTO in ovarian aging

(2020) Xiaoyan Sun et al.   ARCHIVES OF GYNECOLOGY AND OBSTETRICS

Steroid metabolome profiling of follicular fluid in normo- and hyperandrogenic women with polycystic ovary syndrome

(2020) Zuwei Yang et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Where, When, and How: Context-Dependent Functions of RNA Methylation Writers, Readers, and Erasers

(2019) Hailing Shi et al.   MOLECULAR CELL

A meta-analysis on associations of FTO, MTHFR and TCF7L2 polymorphisms with polycystic ovary syndrome

(2019) Xiye Wang et al.   GENOMICS

Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome†‡

(2018) Helena J Teede et al.   HUMAN REPRODUCTION

Glucose is involved in the dynamic regulation of m6A in patients with type 2 diabetes

(2018) Ying Yang et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Differential m6A, m6Am, and m1A Demethylation Mediated by FTO in the Cell Nucleus and Cytoplasm

(2018) Jiangbo Wei et al.   MOLECULAR CELL

A Summary on Polycystic Ovary Syndrome: Diagnostic Criteria, Prevalence, Clinical Manifestations, and Management According to the Latest International Guidelines

(2018) Adriana Neven et al.   SEMINARS IN REPRODUCTIVE MEDICINE

Characteristics of obesity in polycystic ovary syndrome: Etiology, treatment, and genetics

(2018) Charles J. Glueck et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

The role of the PI3K-Akt signaling pathway in the developmental competence of bovine oocytes

(2017) Gabriella Mamede Andrade et al.   PLoS One

Criteria, prevalence, and phenotypes of polycystic ovary syndrome

(2016) Daria Lizneva et al.   FERTILITY AND STERILITY

Prostate specific antigen (PSA) in diagnosis of polycystic ovarian syndrome – a new insight

(2016) Ewa Rudnicka et al.   GYNECOLOGICAL ENDOCRINOLOGY

The prevalence and phenotypic features of polycystic ovary syndrome: a systematic review and meta-analysis

(2016) Gurkan Bozdag et al.   HUMAN REPRODUCTION

Metformin Regulates Ovarian Angiogenesis and Follicular Development in a Female Polycystic Ovary Syndrome Rat Model

(2015) Mariana Di Pietro et al.   ENDOCRINOLOGY

The bigger picture of FTO—the first GWAS-identified obesity gene

(2013) Ruth J. F. Loos et al.   Nature Reviews Endocrinology

The FTO Gene rs9939609 Polymorphism Predicts Risk of Cardiovascular Disease: A Systematic Review and Meta-Analysis

(2013) Chibo Liu et al.   PLoS One

N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

(2011) Guifang Jia et al.   Nature Chemical Biology

Large effects on body mass index and insulin resistance of fat mass and obesity associated gene (FTO) variants in patients with polycystic ovary syndrome (PCOS)

(2010) Susanne Tan et al.   BMC Medical Genetics

Steroid profiles in ovarian follicular fluid in women with and without polycystic ovary syndrome, analyzed by liquid chromatography-tandem mass spectrometry

(2010) Tord Naessen et al.   FERTILITY AND STERILITY

The FTO gene modifies weight, fat mass and insulin sensitivity in women with polycystic ovary syndrome, where its role may be larger than in other phenotypes

(2009) I. Kowalska et al.   DIABETES & METABOLISM

Expression of 11β-hydroxysteroid dehydrogenase 1 and 2 in subcutaneous adipose tissue of lean and obese women with and without polycystic ovary syndrome

(2009) P F Svendsen et al.   INTERNATIONAL JOURNAL OF OBESITY

The Androgen Excess and PCOS Society criteria for the polycystic ovary syndrome: the complete task force report

(2008) Ricardo Azziz et al.   FERTILITY AND STERILITY