4.7 Article

DNA-templated in situ growth of silver nanoparticles on mesoporous silica nanospheres for smart intracellular GSH-controlled release

Journal

CHEMICAL COMMUNICATIONS
Volume 51, Issue 30, Pages 6544-6547

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc00557d

Keywords

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Funding

  1. National Natural Science Foundation of China [21135001, 21305036, 21405038, J1103312]
  2. 973'' National Key Basic Research Program [2011CB91100-0]

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In this work, we propose a method for constructing silver nanoparticles (AgNPs) on mesoporous silica nanospheres (MSNs) by a DNA-templated process. By in situ formation, the gatekeeper can be easily modulated to meet different degrees of glutathione (GSH) stimuli for location-specific drug release.

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