Defining the metal binding pathways of human metallothionein 1a: balancing zinc availability and cadmium seclusion

Advances in the molecular understanding of biological zinc transport

(2015) Claudia A. Blindauer   CHEMICAL COMMUNICATIONS

Chronic inorganic arsenic exposure in vitro induces a cancer cell phenotype in human peripheral lung epithelial cells

(2015) Rachel J. Person et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Metallothionein blocks oxidative DNA damage induced by acute inorganic arsenic exposure

(2015) Wei Qu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The Zinc Balance: Competitive Zinc Metalation of Carbonic Anhydrase and Metallothionein 1A

(2014) Tyler B. J. Pinter et al.   BIOCHEMISTRY

Metalation Kinetics of the Human α-Metallothionein 1a Fragment Is Dependent on the Fluxional Structure of the apo-Protein

(2014) Gordon W. Irvine et al.   CHEMISTRY-A EUROPEAN JOURNAL

Chemically and Biologically Harmless versus Harmful Ferritin/Copper-Metallothionein Couples

(2014) Fernando Carmona et al.   CHEMISTRY-A EUROPEAN JOURNAL

In vivo-folded metal-metallothionein 3 complexes reveal the Cu-thionein rather than Zn-thionein character of this brain-specific mammalian metallothionein

(2014) Ester Artells et al.   FEBS Journal

High metal substitution tolerance of anthrax lethal factor and characterization of its active copper-substituted analogue

(2014) Suet Y. Lo et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Metal-Induced Conformational Changes of Human Metallothionein-2A: A Combined Theoretical and Experimental Study of Metal-Free and Partially Metalated Intermediates

(2014) Shu-Hua Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Combining Chemical Labeling, Bottom-Up and Top-Down Ion-Mobility Mass Spectrometry To Identify Metal-Binding Sites of Partially Metalated Metallothionein

(2013) Shu-Hua Chen et al.   ANALYTICAL CHEMISTRY

Topographical analysis of As-induced folding of α-MT1a

(2013) Gordon W. Irvine et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Single-Domain Metallothioneins: Evidence of the Onset of Clustered Metal Binding Domains in Zn-rhMT 1a

(2013) Kelly L. Summers et al.   BIOCHEMISTRY

The Role of Metallothionein in Oxidative Stress

(2013) Branislav Ruttkay-Nedecky et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The major function of a metallothionein from the aquatic fungus Heliscus lugdunensis is cadmium detoxification

(2013) Jens Loebus et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Lessons on the critical interplay between zinc binding and protein structure and dynamics

(2013) Claudia A. Blindauer   JOURNAL OF INORGANIC BIOCHEMISTRY

Mammalian MT1 and MT2 metallothioneins differ in their metal binding abilities

(2013) Ester Artells et al.   Metallomics

Metallothioneins (MTs) in the human eye: a perspective article on the zinc–MT redox cycle

(2013) Héctor Gonzalez-Iglesias et al.   Metallomics

The liver in itai-itai disease (chronic cadmium poisoning): pathological features and metallothionein expression

(2013) Hayato Baba et al.   MODERN PATHOLOGY

Signals from the lysosome: a control centre for cellular clearance and energy metabolism

(2013) Carmine Settembre et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Copper Homeostasis at the Host-Pathogen Interface: FIGURE 1.

(2012) Victoria Hodgkinson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Single Domain Metallothioneins: Supermetalation of Human MT 1a

(2012) Duncan E. K. Sutherland et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Metals on the move: zinc ions in cellular regulation and in the coordination dynamics of zinc proteins

(2011) Wolfgang Maret   BIOMETALS

Copper: An essential metal in biology

(2011) Richard A. Festa et al.   CURRENT BIOLOGY

Roles of copper chaperone for superoxide dismutase 1 and metallothionein in copper homeostasis

(2011) Takamitsu Miyayama et al.   Metallomics

The “magic numbers” of metallothionein

(2011) Duncan E. K. Sutherland et al.   Metallomics

Molecular mechanisms of cisplatin resistance

(2011) L Galluzzi et al.   ONCOGENE

Role of Arf1 in endosomal trafficking of protein–metal complexes and cadmium–metallothionein-1 toxicity in kidney proximal tubule cells

(2011) Natascha A. Wolff et al.   TOXICOLOGY LETTERS

Reactivity of polynuclear zinc-thiolate sites

(2010) Gilles Ohanessian et al.   INTERNATIONAL JOURNAL OF QUANTUM CHEMISTRY

Electrospray ionization mass spectrometry of zinc, cadmium, and copper metallothioneins: Evidence for metal-binding cooperativity

(2010) Peter M. Gehrig et al.   PROTEIN SCIENCE

Reactivity of an antimetastatic organometallic ruthenium compound with metallothionein-2: relevance to the mechanism of action

(2009) Angela Casini et al.   Metallomics

Current status of cadmium as an environmental health problem

(2009) Lars Järup et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Noncooperative cadmium(II) binding to human metallothionein 1a

(2008) Duncan E.K. Sutherland et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Metallothionein/Thionein System: An Oxidoreductive Metabolic Zinc Link

(2008) Stephen G. Bell et al.   CHEMBIOCHEM

Metal exchange in metallothioneins - a novel structurally significant Cd5 species in the alpha domain of human metallothionein 1a

(2008) Kelly E. Rigby Duncan et al.   FEBS Journal

Metallothionein-Cross-Linked Hydrogels for the Selective Removal of Heavy Metals from Water

(2008) Aaron P. Esser-Kahn et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Kinetic Analysis of Arsenic−Metalation of Human Metallothionein: Significance of the Two-Domain Structure

(2008) Thanh T. Ngu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Metallothionein redox biology in the cytoprotective and cytotoxic functions of zinc

(2007) Wolfgang Maret   EXPERIMENTAL GERONTOLOGY