Defining potential roles of Pb2+in neurotoxicity from a calciomics approach

Biochemical and biophysical characterization of a plant calmodulin: Role of the N- and C-lobes in calcium binding, conformational change, and target interaction

(2016) Alessandra Astegno et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Fast kinetics of calcium signaling and sensor design

(2015) Shen Tang et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Neuronal Calcium Sensor-1 Binds the D2 Dopamine Receptor and G-protein-coupled Receptor Kinase 1 (GRK1) Peptides Using Different Modes of Interactions

(2015) Sravan Pandalaneni et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Presynaptic Mechanisms of Lead Neurotoxicity: Effects on Vesicular Release, Vesicle Clustering and Mitochondria Number

(2015) Xiao-lei Zhang et al.   PLoS One

Stim and Orai proteins in neuronal Ca2+ signaling and excitability

(2015) Francesco Moccia et al.   Frontiers in Cellular Neuroscience

Interaction of metal ions with neurotransmitter receptors and potential role in neurodiseases

(2014) Carla Marchetti   BIOMETALS

Novel dose-dependent alterations in excitatory GABA during embryonic development associated with lead (Pb) neurotoxicity

(2014) Sara E. Wirbisky et al.   TOXICOLOGY LETTERS

Extracellular Calcium Modulates Actions of Orthosteric and Allosteric Ligands on Metabotropic Glutamate Receptor 1α

(2013) Jason Y. Jiang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metal toxicity and opportunistic binding of Pb2+ in proteins

(2013) Michael Kirberger et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Mechanisms of lead and manganese neurotoxicity

(2013) April P. Neal et al.   Toxicology Research

Crystallographic snapshots of initial steps in the collapse of the calmodulin central helix

(2013) Petri Kursula   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Relating Form and Function of EF-Hand Calcium Binding Proteins

(2011) Walter J. Chazin   ACCOUNTS OF CHEMICAL RESEARCH

Trace metal contamination in urban soils of China

(2011) Xiao-san Luo et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Activation of TRPC Cationic Channels by Mercurial Compounds Confers the Cytotoxicity of Mercury Exposure

(2011) Shang-Zhong Xu et al.   TOXICOLOGICAL SCIENCES

Exposures to lead

(2011) Anna C. Callan et al.   REVIEWS ON ENVIRONMENTAL HEALTH

Stimulation of TRPC5 cationic channels by low micromolar concentrations of lead ions (Pb2+)

(2010) Piruthivi Sukumar et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Site-specific modification of calmodulin Ca2+affinity tunes the skeletal muscle ryanodine receptor activation profile

(2010) Jie Jiang et al.   BIOCHEMICAL JOURNAL

Calmodulin Controls Synaptic Strength via Presynaptic Activation of Calmodulin Kinase II

(2010) Z. P. Pang et al.   JOURNAL OF NEUROSCIENCE

Development of light response and GABAergic excitation-to-inhibition switch in zebrafish retinal ganglion cells

(2010) Rong-wei Zhang et al.   JOURNAL OF PHYSIOLOGY-LONDON

Molecular Neurobiology of Lead (Pb2+): Effects on Synaptic Function

(2010) April P. Neal et al.   MOLECULAR NEUROBIOLOGY

Lead exposure during synaptogenesis alters NMDA receptor targeting via NMDA receptor inhibition

(2010) April P. Neal et al.   NEUROTOXICOLOGY

Analysis and prediction of calcium-binding pockets from apo-protein structures exhibiting calcium-induced localized conformational changes

(2010) Xue Wang et al.   PROTEIN SCIENCE

Assessing heavy-metal contamination and sources by GIS-based approach and multivariate analysis of urban–rural topsoils in Wuhan, central China

(2009) Min Gong et al.   ENVIRONMENTAL GEOCHEMISTRY AND HEALTH

Frequenin/NCS-1 and the Ca2+-channel  1-subunit co-regulate synaptic transmission and nerve-terminal growth

(2009) J. S. Dason et al.   JOURNAL OF CELL SCIENCE

The use of ESI-MS to probe the binding of divalent cations to calmodulin

(2009) Sally L. Shirran et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Stress, memory and the amygdala

(2009) Benno Roozendaal et al.   NATURE REVIEWS NEUROSCIENCE

The 1H NMR structure of bovine Pb2+-osteocalcin and implications for lead toxicity

(2008) T.L Dowd et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

The blood–CSF barrier explained: when development is not immaturity

(2008) Pia A. Johansson et al.   BIOESSAYS

Statistical analysis of structural characteristics of protein Ca2+-binding sites

(2008) Michael Kirberger et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Structural differences between Pb2+- and Ca2+-binding sites in proteins: Implications with respect to toxicity

(2008) Michael Kirberger et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

G-Protein-Coupled Receptor Screen Reveals a Role for Chemokine Receptor CCR5 in Suppressing Microglial Neurotoxicity

(2008) K. Gamo et al.   JOURNAL OF NEUROSCIENCE

Calmodulin dynamically regulates the trafficking of the metabotropic glutamate receptor mGluR5

(2008) J. H. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Energetics of calmodulin domain interactions with the calmodulin binding domain of CaMKII

(2008) T. Idil Apak Evans et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Towards predicting Ca2+-binding sites with different coordination numbers in proteins with atomic resolution

(2008) Xue Wang et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Blood Lead Concentrations < 10 μg/dL and Child Intelligence at 6 Years of Age

(2007) Todd A. Jusko et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Molecular determinants of Pb2+ interaction with NMDA receptor channels

(2007) Paola Gavazzo et al.   NEUROCHEMISTRY INTERNATIONAL